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TABLE OF CONTENTS
SECTION 1: EXECUTIVE SUMMARY
1.1 Suture Market
1.2 Stapling Market
1.3 Wound Closure Strip Market
1.4 Surgical Sealant and Glue
Market
1.5 Energy-Based Closure Device
Market
1.6 Automated Suturing Device
Market
SECTION 2: CLINICAL OVERVIEW
2.1 The Physiology of Wound
Closure
2.1.1 The Layers of the Skin and
Supporting Structures
2.1.1.1 Epidermis
2.1.1.2 Dermis
2.1.1.3 Subcutaneous Tissue
2.1.1.4 Fascia
2.1.1.5 Muscle
2.1.1.6 Bone
2.1.2 The Wound Closure Process
2.1.2.1 Hemostasis
2.1.2.2 Inflammation
2.1.2.3 Proliferation
2.1.2.4 Remodeling Phase
2.2 Factors Affecting Wound
Closure
2.2.1 Intrinsic Factors
2.2.1.1 Body Build
2.2.1.2 Chronic Illness and Age
2.2.1.3 Nutrition
2.2.2 Extrinsic Factors
2.2.2.1 Desiccation
2.2.2.2 Hydration
2.2.2.3 Infection
2.2.2.4 Maceration
2.2.2.5 Medications and Other
Treatment Modalities
2.2.2.6 Necrotic Tissue and
Debris
2.2.2.7 Oxygen
2.2.2.8 Stress
2.2.2.9 Temperature
2.2.2.10 Wound Creation and
Depth
2.2.2.11 Wound Closure
Techniques
2.2.2.12 Other Extrinsic Factors
2.2.3 Complications of Wound
Healing
2.2.3.1 Scarring
2.2.3.2 Bleeding
2.3 The Major Wound Types
2.3.1 Amputations
2.3.2 Arterial Ulcers
2.3.3 Burns
2.3.4 Diabetic Ulcers
2.3.5 Pressure Ulcers
2.3.5.1 Staging of Pressure Ulcers
2.3.6 Surgical Wounds
2.3.7 Traumatic
Wounds/Lacerations
2.3.8 Venous Ulcers
2.4 The Incidence of Major Wound
Types
SECTION 3: TRADITIONAL WOUND CLOSURE PRODUCTS
3.1 Sutures
3.1.1 Suture Classifications
3.1.1.1 Monofilament and
Multifilament Sutures
3.1.1.2 Nonabsorbable and
Absorbable Sutures
3.1.1.2.1 Nonabsorbable Sutures
3.1.1.2.2 Absorbable Sutures
3.1.2 Competitors and Their
Products
3.1.2.1
Competitive Analysis
3.1.3 Market Forecast
3.1.4 Competitive Analysis
3.2 Staplers
3.2.1 Types of Staplers and
Staples
3.2.2 Competitors and Their
Products
3.2.2.1 Competitive Analysis
3.2.3 Market Forecast
3.2.4 Competitive Analysis
3.3 Wound Closure Strips
3.3.1 Competitors and Their
Products
3.3.1.1 Competitive Analysis
3.3.2 Market Forecast
3.3.3 Competitive Analysis
SECTION 4: EMERGING TRENDS IN WOUND CLOSURE
4.1 Surgical Sealants and Glues
4.1.1 Applications of Surgical
Sealants and Glues
4.1.1.1 Cardiac and Vascular
Surgeries
4.1.1.2 General Surgery
4.1.1.3 Thoracic Surgery
4.1.1.4 Plastic and Ear, Nose,
and Throat Surgeries
4.1.1.5 Neurosurgery/Spine
Surgery
4.1.2 Fibrin Sealants
4.1.2.1 Composition
4.1.2.2 Application Methods
4.1.2.3 Competitive Analysis
4.1.3 Autologous-Processed
Sealants
4.1.3.1 Competitive Analysis
4.1.4 Collagen- and
Albumin-Based Sealants
4.1.4.1 Collagen-Based Sealants
4.1.4.1.1 Competitive Analysis
4.1.4.2 Albumin-Based Sealants
4.1.4.2.1 Competitive Analysis
4.1.5 Cyanoacrylate-Based
Sealants
4.1.5.1 Competitive Analysis
4.1.6 Polymer-Based Sealants
4.1.6.1 Competitive Analysis
4.1.7 Market Analysis
4.1.7.1 Market Forecast
4.1.7.2 Competitive Analysis
4.2 Energy-Based Closure
4.2.1 Radiofrequency
4.2.1.1 Monopolar versus Bipolar
4.2.1.2 Competitors and Their Products
4.2.1.2.1 Competitive Analysis
4.2.2 Ultrasonic
Suturing/Closure
4.2.2.1 Competitive Analysis
4.2.3 Thermal
4.2.3.1 Competitive Analysis
4.2.4 Market Forecast
4.2.5 Competitive Analysis
4.3 Automated
Suturing Devices
4.3.1 Competitors and Their
Products
4.3.1.1
Competitive Analysis
4.3.2 Market Forecast
4.3.3 Competitive Analysis
SECTION 5: COMPANY PROFILES
5.1 3M COMPANY
5.2 AXYA MEDICAL, INC.
5.3 BAXTER INTERNATIONAL, INC.
5.4 BTG INTERNATIONAL, INC.
5.5 CLOSURE MEDICAL CORPORATION
5.6 COHESION TECHNOLOGIES, INC.
5.7 CRYOLIFE, INC.
5.8 GENZYME BIOSURGERY, INC.
5.9 HAEMACURE CORPORATION
5.10 HENKEL LOCTITE CORPORATION
5.11 INTERPORE CROSS
INTERNATIONAL, INC.
5.12 JOHNSON & JOHNSON
5.13 PPL THERAPEUTICS PLC
5.14 THERMOGENESIS CORPORATION
5.15 TYCO HEALTHCARE
APPENDIX A: COMPANY LISTING
LIST OF EXHIBITS
Exhibit 1-1: Sutures, U.S. Market Forecast, 2001-2011E
Exhibit 1-2: Surgical Staplers, U.S. Market Forecast,
2001-2011E
Exhibit 1-3: Wound Closure Strips, U.S. Market Forecast,
2001-2011E
Exhibit 1-4: Surgical Sealants and Glues, U.S. Market
Forecast, 2001-2011E
Exhibit 1-5: Energy-Based Closure Devices, U.S. Market
Forecast, 2001-2011E
Exhibit 1-6: Automated Suturing Devices, U.S. Market
Forecast, 2001-2011E
Exhibit 2-1: The Skin’s Layers and Supporting
Structures
Exhibit 2-2: Phases Involved in the Wound Closure Process
Exhibit 2-3: Intrinsic and Extrinsic Factors Affecting
Wound Closure
Exhibit 2-4: Major Wound Types
Exhibit 2-5: U.S. Inpatient and Outpatient Surgical
Procedure Volumes, 2001
Exhibit 2-6: U.S. Incidence of Major Wound Types, 2001
Exhibit 3-1: Selected Suture Products, by Manufacturer
Exhibit 3-2: Sutures, U.S. Market Forecast, 2001-2011E
Exhibit 3-3: U.S. Suture Market, Share by Supplier, 2001
Exhibit 3-4: Selected Surgical Stapler Products, by
Manufacturer
Exhibit 3-5: Surgical Staplers, U.S. Market Forecast,
2001-2011E
Exhibit 3-6: U.S. Surgical Stapler Market, Share by
Supplier, 2001
Exhibit 3-7: Selected Wound Closure Strip Products, by
Manufacturer
Exhibit 3-8: Wound Closure Strips, U.S. Market Forecast,
2001-2011E
Exhibit 3-9: U.S. Wound Closure Strip Market, Share by
Supplier, 2001
Exhibit 4-1: Mode of Action of Surgical Sealants and
Glues
Exhibit 4-2: Comparison of Properties of Fibrin Sealants
and Cyanoacrylates
Exhibit 4-3: Usage of Surgical Sealants and Glues, by
Specialty
Exhibit 4-4: Major Applications for Surgical Sealants and
Glues in Cardiac and Vascular Surgeries
Exhibit 4-5: Major Applications for Surgical Sealants and
Glues in General Surgery
Exhibit 4-6: Major Applications for Surgical Sealants and
Glues in Thoracic Surgery
Exhibit 4-7: Indications for Use of COHESION
TECHNOLOGIES’ CoStasis
Exhibit 4-8: FUSION MEDICAL TECHNOLOGIES/BAXTER’s
FloSeal
Exhibit 4-9: Surgical Sealant Products in Development by
SURGICAL SEALANTS
Exhibit 4-10: Surgical Sealant Products from TISSUEMED
Exhibit 4-11: Characteristics of Cyanoacrylate Glues
Exhibit 4-12: Selected Cyanoacrylate Tissue Adhesives
Exhibit 4-13: MEDLOGIC GLOBAL’s Product Portfolio
Exhibit 4-14: Use of MEDAFOR's TraumaDEX in Wounds
Exhibit 4-15: Recent Merger and Acquisition Activity in
the Surgical Sealant and Glue Market
Exhibit 4-16: Selected Participants in the Surgical
Sealant and Glue Market
Exhibit 4-17: Surgical Sealants and Glues, U.S. Market
Forecast, 2001-2011E
Exhibit 4-18: U.S. Surgical Sealants and Glues Market,
Share by Supplier, 2001
Exhibit 4-19: The Effect of Temperature on Collagenous
Tissue
Exhibit 4-20: Features of GYRUS MEDICAL’s PlasmaKinetic
Tissue Management System
Exhibit 4-21: Advantages of TISSUELINK’s Floating Ball
Platform Technology
Exhibit 4-22: VALLEYLAB’s Line of LigaSure Products
Exhibit 4-23: Components of the AXYA MEDICAL AxyaWeld
Technology
Exhibit 4-24: Energy-Based Closure Devices, U.S. Market
Forecast, 2001-2011E
Exhibit 4-25: U.S. Energy-Based Closure Devices Market,
Share by Supplier, 2001
Exhibit 4-26: The BARD EndoCinch Procedure
Exhibit 4-27: NDO SURGICAL’s Plicator
Exhibit 4-28: SUTURTEK’s FastClose Device
Exhibit 4-29: Automated Suturing Devices, U.S. Market
Forecast, 2001-2011E
Exhibit 4-30: U.S. Automated Suturing Devices Market,
Share by Supplier, 2001
Copyright 2002, Medtech Insight, LLC
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