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U.S. Markets for Stroke Management Products
November 2004, 301 pages
Report #A225

Stroke—a sudden and often catastrophic disruption in the delivery of oxygen and nutrients to the tissues of the brain—is the third-leading cause of death in the U.S., following heart disease and cancer. It is estimated that there will be 282,000 fatalities due to stroke in 2004, half of which will occur outside a hospital. Products used to manage stroke patients include diagnostic imaging systems, pharmaceuticals, and surgical and interventional systems. The U.S. market for these products, which was worth approximately $3.6 billion in 2003, is expected to reach a value of nearly $6.0 billion by the year 2008.

This dynamic report from Medtech Insight includes analyses of products, technologies, current and forecast markets, competitors, and opportunities in the U.S. stroke management products market. Topics covered in this report include arteriovenous malformation/cerebral aneurysm clipping, carotid artery stenting, carotid endarterectomy, cerebral angiography, computed tomography, cooling technologies, drug therapy, embolic protection, endovascular embolization, endovascular thrombectomy, magnetic resonance imaging, nuclear medicine imaging, radiosurgery, and ultrasound.

Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

TABLE OF CONTENTS

EXECUTIVE SUMMARY

i. Stroke Epidemiology Trends

ii. Diagnostic/Therapeutic Stroke Management Procedures

iii. Stroke Management Products Market

a. Diagnostic Imaging Systems

b. Drug Therapy Products

c. Surgical/Interventional Devices

1. CLINICAL AND STATISTICAL OVERVIEW OF STROKE

1.1 Etiology

1.2 Types

1.2.1 Hemorrhagic

1.2.1.1 Intracerebral

1.2.1.1.1 Symptoms and Risk Factors

1.2.1.1.2 Diagnostic and Therapeutic Management

1.2.1.2 Subarachnoid

1.2.1.2.1 Symptoms and Risk Factors

1.2.1.2.2 Diagnostic and Therapeutic Management

1.2.2 Ischemic

1.2.2.1 Embolic

1.2.2.2 Hypoperfusion

1.2.2.3 Thrombotic

1.2.2.4 Transient Ischemic Attack

1.2.2.5 Symptoms and Risk Factors

1.2.2.6 Diagnostic and Therapeutic Management

1.3 Epidemiology

1.4 Incidence

1.4.1 Demographics

1.4.2 Morbidity and Mortality

2. CLINICAL MANAGEMENT OF STROKE

2.1 Stroke Diagnostics

2.1.1 Computed Tomography

2.1.1.1 Spiral Computed Tomography

2.1.1.2 Computed Tomography Angiography

2.1.1.3 Electron Beam Computed Tomography

2.1.1.4 Perfusion Weighted Computed Tomography

2.1.1.5 Stroke-Related Applications

2.1.1.5.1 Procedure Volumes Forecast

2.1.2 Magnetic Resonance Imaging

2.1.2.1 Magnetic Resonance Angiography

2.1.2.1.1 Time-of-Flight Magnetic Resonance Angiography

2.1.2.1.2 Phase-Contrast Magnetic Resonance Angiography

2.1.2.1.3 Contrast-Enhanced Magnetic Resonance Angiography

2.1.2.2 Echo Planar Magnetic Resonance Imaging

2.1.2.3 Perfusion Magnetic Resonance Imaging

2.1.2.4 Diffusion Magnetic Resonance Imaging

2.1.2.5 Stroke-Related Applications

2.1.2.5.1 Procedure Volumes Forecast

2.1.3 Diagnostic Ultrasound

2.1.3.1 Doppler Ultrasound

2.1.3.2 Duplex Ultrasound

2.1.3.3 Stroke-Related Applications

2.1.3.3.1 Procedure Volumes Forecast

2.1.4 Conventional Cerebral Angiography

2.1.4.1 Biplane Angiography

2.1.4.2 Stroke-Related Applications

2.1.4.2.1 Procedure Volumes Forecast

2.1.5 Nuclear Imaging

2.1.5.1 Gamma Camera Imaging

2.1.5.2 Positron Emission Tomography

2.1.5.3 Stroke-Related Applications

2.1.5.3.1 Procedure Volumes Forecast

2.2 Therapeutic Management of Stroke

2.2.1 Pharmacological Therapeutic Modalities

2.2.1.1 Nonsteroidal Anti-Inflammatory Drug Therapy

2.2.1.1.1 Caseload Forecast

2.2.1.2 Antiplatelet Drug Therapy

2.2.1.2.1 Caseload Forecast

2.2.1.3 Anticoagulation Drug Therapy

2.2.1.3.1 Caseload Forecast

2.2.1.4 Antihypertensive Drug Therapy

2.2.1.4.1 Caseload Forecast

2.2.1.5 Oral Anticonvulsive Drug Therapy

2.2.1.5.1 Caseload Forecast

2.2.1.6 Thrombolytic Drug Therapy

2.2.1.6.1 Caseload Forecast

2.2.1.7 Emerging Stroke-Related Drug Therapies

2.2.1.7.1 Nerve Blockers

2.2.1.7.2 Statins

2.2.2 Stroke-Related Surgical and Endovascular Interventions

2.2.2.1 Carotid Endarterectomy

2.2.2.1.1 Procedure Volumes Forecast

2.2.2.2 Endovascular Embolization

2.2.2.2.1 Procedure Volumes Forecast

2.2.2.3 Gamma Knife Radiosurgery

2.2.2.3.1 Procedure Volumes Forecast

2.2.2.4 Surgical Clipping

2.2.2.4.1 Procedure Volumes Forecast

2.2.2.5 Emerging Stroke-Related Endovascular Therapies

2.2.2.5.1 Blood Diverting Catheterization

2.2.2.5.2 Carotid Artery Stenting

2.2.2.5.3 Cooling Technologies

2.2.2.5.4 Embolic Protection

2.2.2.5.5 Endovascular Thrombectomy

3. STROKE MANAGEMENT RESOURCES AND INITIATIVES

3.1 Hospitals and Critical Care Facilities

3.1.1 Telemedicine Initiatives

3.2 Groups and Associations

3.2.1 American Heart Association

3.2.2 Brain Attack Coalition

3.2.3 National Institute of Neurological Disorders and Stroke

3.2.4 National Stroke Association

3.3 Stroke Treatment and Ongoing Prevention Stroke Act of 2003

3.4 Emerging Stroke Prevention Therapies

3.4.1 Stem Cell Therapy

3.4.2 Vaccines

3.5 Basic Research

3.5.1 Chemical Predictors of Stroke

3.5.2 Genetically Engineered Drugs

3.5.3 Gene Therapy

4. STROKE MANAGEMENT PRODUCTS MARKET

4.1 Diagnostic Imaging Systems

4.1.1 Computed Tomography Systems

4.1.1.1 Market Forecast

4.1.1.2 Competitive Analysis

4.1.2 Magnetic Resonance Imaging Systems

4.1.2.1 Market Forecast

4.1.2.2 Competitive Analysis

4.1.3 Diagnostic Ultrasound Systems

4.1.3.1 Market Forecast

4.1.3.2 Competitive Analysis

4.1.4 Angiography Systems

4.1.4.1Market Forecast

4.1.4.2 Competitive Analysis

4.1.5Nuclear Imaging Systems

4.1.5.1 Market Forecast

4.1.5.2 Competitive Analysis

4.1.6 Combined Market Forecast for Stroke-Related Diagnostic Imaging Products

4.2 Drug Therapy Products

4.2.1 Nonsteroidal Anti-Inflammatory Drugs

4.2.1.1 Market Forecast

4.2.1.2 Competitive Analysis

4.2.2 Oral Prescription Antiplatelet Agents

4.2.2.1 Market Forecast

4.2.2.2 Competitive Analysis

4.2.3 Oral Anticoagulation Agents

4.2.3.1 Market Forecast

4.2.3.2 Competitive Analysis

4.2.4 Oral Antihypertensive Agents

4.2.4.1 Market Forecast

4.2.4.2 Competitive Analysis

4.2.5 Oral Anticonvulsive Agents

4.2.5.1 Market Forecast

4.2.5.2 Competitive Analysis

4.2.6 Intravenous Thrombolytic Agents

4.2.6.1 Market Forecast

4.2.6.2 Competitive Analysis

4.2.7 Combined Market Forecast for Stroke-Related Pharmaceuticals

4.3 Neurovascular Surgical and Interventional Products

4.3.1 Aneurysm/Arteriovenous Malformation Surgical Clip Systems

4.3.1.1 Market Forecast

4.3.1.2 Competitive Analysis

4.3.2 Endovascular Embolization Systems

4.3.2.1 Market Forecast

4.3.2.2 Competitive Analysis

4.3.3 Emerging Interventional Systems for Stroke

4.3.3.1 Embolic Protection Systems

4.3.3.1.1 Market Forecast

4.3.3.1.2 Competitive Analysis

4.3.3.2 Carotid Artery Stenting Systems

4.3.3.2.1 Market Forecast

4.3.3.3 Microcatheter-Based Cerebral Thrombectomy Systems

4.3.3.3.1 Market Forecast

4.3.3.4 Cooling Technologies

4.3.3.5 Combined Market Forecast for Emerging Stroke-Related Interventional Therapy Systems

4.3.4 Combined Market Forecast for Stroke-Related Surgical and Interventional Products

4.4 Combined Market Forecast for Stroke Management Products

5. COMPANY PROFILES

5.1 Abbott Laboratories

5.2 Aesculap, Inc./B. Braun Melsungen AG

5.3 Boston Scientific Corporation

5.4 Concentric Medical, Inc.

5.5 Cook Group

5.6 GE Healthcare, Inc./General Electric Company

5.7 Genentech, Inc.

5.8 Guidant Corporation

5.9 Johnson & Johnson

5.10 Medtronic, Inc.

5.11 Mizuho America, Inc./Mizuho Medical Company LTD

5.12 Pfizer, Inc.

5.13 Philips Medical Systems, Inc./Royal Philips Electronics NV

5.14 Siemens Medical Solutions, Inc./Siemens AG

APPENDIX: COMPANY LISTING

LIST OF EXHIBITS

Exhibit ES-1: Stroke Incidence, 2003 and 2008

Exhibit ES-2: Diagnostic Imaging, Drug Therapy, and Neurovascular Intervention/Surgery for Stroke-Related Applications, Caseload and Procedure Volumes Forecast, 2003-2008

Exhibit ES-3: Stroke Management Products, Combined Market Forecast, 2003-2008

Exhibit ES-4: Stroke-Related Diagnostic Imaging Products, Combined Market Forecast, 2003-2008

Exhibit ES-5: Stroke-Related Drug Therapy Products, Market Forecast, 2003-2008

Exhibit ES-6: Stroke-Related Surgical and Interventional Products, Market Forecast, 2003-2008

Exhibit 2-1: Computed Tomography, Procedure Volumes Forecast, 2003-2008

Exhibit 2-2: Magnetic Resonance Imaging, Procedure Volumes Forecast, 2003-2008

Exhibit 2-3: Ultrasound, Procedure Volumes Forecast, 2003-2008

Exhibit 2-4: Angiography, Procedure Volumes Forecast, 2003-2008

Exhibit 2-5: Nuclear Imaging, Procedure Volumes Forecast, 2003-2008

Exhibit 2-6: Nonsteroidal Anti-Inflammatory Drug Therapy, Patient Caseload Forecast, 2003-2008

Exhibit 2-7: Antiplatelet Drug Therapy, Patient Caseload Forecast, 2003-2008

Exhibit 2-8: Warfarin Therapy, Patient Caseload Forecast, 2003-2008

Exhibit 2-9: Antihypertensive Therapy, Patient Caseload Forecast, 2003-2008

Exhibit 2-10: Anticonvulsive Therapy, Patient Caseload Forecast, 2003-2008

Exhibit 2-11: Thrombolytic Drug Therapy, Patient Caseload Forecast, 2003-2008

Exhibit 2-12: 2004, Selected Clinical Trials of Pharmacological Stroke Remedies

Exhibit 2-13: Carotid Endarterectomy, Procedure Volumes Forecast, 2003-2008

Exhibit 2-14: Endovascular Embolization, Procedure Volumes Forecast, 2003-2008

Exhibit 2-15: Gamma Knife Radiosurgery, Procedure Volumes Forecast, 2003-2008

Exhibit 2-16: Surgical Clipping of Cerebral Aneurysms and Arteriovenous Malformations, Procedure Volumes Forecast, 2003-2008

Exhibit 2-17: Carotid Artery Stenting, Procedure Volumes Forecast, 2003-2008

Exhibit 2-18: Cooling Technologies, Procedure Volumes Forecast, 2003-2008

Exhibit 2-19: 2004, Current and Emerging Embolic Protection Systems

Exhibit 2-20: Embolic Protection, Procedure Volumes Forecast, 2003-2008

Exhibit 2-21: Endovascular Thrombectomy and Intravenous Thrombolysis, Procedure Volumes Forecast, 2003-2008

Exhibit 4-1: Computed Tomography Systems, Market Forecast, 2003-2008

Exhibit 4-2: 2003, Computed Tomography Systems Market, Share by Supplier

Exhibit 4-3: Magnetic Resonance Imaging Systems, Market Forecast, 2003-2008

Exhibit 4-4: 2003, Magnetic Resonance Imaging Systems Market, Share by Supplier

Exhibit 4-5: Ultrasound Systems, Market Forecast, 2003-2008

Exhibit 4-6: 2003, Ultrasound Systems Market, Share by Supplier

Exhibit 4-7: Angiography Systems, Market Forecast, 2003-2008

Exhibit 4-8: 2003, Angiography Systems Market, Share by Supplier

Exhibit 4-9: Nuclear Imaging Systems, Market Forecast, 2003-2008

Exhibit 4-10: 2003, Nuclear Imaging Systems Market, Share by Supplier

Exhibit 4-11: Stroke-Related Diagnostic Imaging, Combined Procedure Volumes Forecast, 2003-2008

Exhibit 4-12: Stroke-Related Diagnostic Imaging Products, Combined Market Forecast, 2003-2008

Exhibit 4-13: Aspirin, Market Forecast, 2003-2008

Exhibit 4-14: 2003, Aspirin Market, Share by Supplier

Exhibit 4-15: Oral Prescription Antiplatelet Agents, Market Forecast, 2003-2008

Exhibit 4-16: 2003, Oral Prescription Antiplatelet Agents Market, Share by Supplier

Exhibit 4-17: Oral Anticoagulants, Market Forecast, 2003-2008

Exhibit 4-18: 2003, Oral Anticoagulants Market, Share by Supplier

Exhibit 4-19: Oral Antihypertensive Agents, Market Forecast, 2003-2008

Exhibit 4-20: 2003, Oral Antihypertensive Agents Market, Share by Supplier

Exhibit 4-21: Oral Anticonvulsive Agents, Market Forecast, 2003-2008

Exhibit 4-22: 2003, Oral Anticonvulsive Agents Market, Share by Supplier

Exhibit 4-23: Intravenous Thrombolytic Agents, Market Forecast, 2003-2008

Exhibit 4-24: Stroke-Related Drug Therapy, Combined Patient Caseload Forecast, 2003-2008

Exhibit 4-25: Stroke-Related Drugs, Combined Market Forecast, 2003-2008

Exhibit 4-26: Cerebral Aneurysm/Arteriovenous Malformation Clips, Market Forecast, 2003-2008

Exhibit 4-27: 2003, Cerebral Aneurysm/Arteriovenous Malformation Clips Market, Share by Supplier

Exhibit 4-28: Endovascular Embolization Agents, Market Forecast, 2003-2008

Exhibit 4-29: Endovascular Embolization Delivery Systems, Market Forecast, 2003-2008

Exhibit 4-30: 2003, Endovascular Embolization Products Market, Share by Supplier

Exhibit 4-31: Embolic Protection Systems, Market Forecast, 2003-2008

Exhibit 4-32: Carotid Artery Stenting Systems, Market Forecast, 2003-2008

Exhibit 4-33: Cerebral Thrombectomy Systems, Market Forecast, 2003-2008

Exhibit 4-34: Cooling Technology Systems, Market Forecast, 2003-2008

Exhibit 4-35: Emerging Interventional Products, Combined Market Forecast, 2003-2008

Exhibit 4-36: Stroke-Related Surgical and Interventional Products, Combined Market Forecast, 2003-2008

Exhibit 4-37: Stroke Management Products, Combined Market Forecast, 2003-2008

Exhibit 5-1: Types of Stroke Management Products Offered by Profiled Companies

Ordering Information

Title	Report #	Publication Date	List Price
U.S. Markets for Stroke Management Products	A225	November 2004	$4,250*

*The pdf version of each report costs an additional $750 when purchased in addition to the hardcopy.

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