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U.S. Markets for Stroke Management Products
Report #A226 - December 2008
340 Pages – 76 Exhibits
19 Company Profiles


In 2007, sales of stroke management products in the United States (U.S.) totaled approximately $4.8 billion, with drug therapy products accounting for approximately 86.1% of sales, diagnostic imaging systems accounting for 7.0% of sales, surgical and endovascular systems for stroke prophylaxis accounting for 6.4% of sales, and cerebrovascular endovascular systems accounting for 0.4% of sales.  Over the forecast period covered by this report, total sales of stroke management products are expected to increase at a compound annual rate of 5.9%, reaching approximately $6.4 billion in the year 2012.

This Medtech Insight report presents an overview of the U.S. stroke management products market, providing procedure volume and market forecasts for diagnostic imaging systems (including cerebral angiography, computed tomography, diagnostic ultrasound, magnetic resonance imaging, and nuclear medicine imaging systems), drug therapy products (including oral anticoagulation, anticonvulsant, antihypertensive, and antiplatelet agents, as well as intravenous thrombolytic agents), surgical and endovascular systems for stroke prophylaxis (including aneurysm and arteriovenous malformation surgical clipping systems, embolization systems, and carotid artery stenting and associated distal embolic protection systems), and cerebrovascular endovascular products (including cerebral perfusion augmentation, embolectomy/thrombectomy, and intracranial stenting systems).

Ordering Information

Title

 Report# Publication
Date		 List Price

U.S. Markets for Stroke Management Products

A226

 December 2008

$4,750
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Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

EXECUTIVE SUMMARY

i.    Current and Emerging Markets for Stroke Management Products

a.   Diagnostic Imaging Systems

i.    Computed Tomography Systems

ii.    Magnetic Resonance Imaging Systems

iii.   Diagnostic Ultrasound Systems

iv.   Nuclear Medicine Imaging Systems

v.   Cerebral Angiography Products

b.   Drug Therapy Products

i.    Oral Anticoagulation Agents

ii.    Oral Antihypertensive Agents

iii.   Oral Antiplatelet Agents

iv.   Oral Anticonvulsant Agents

v.   Intravenous Thrombolytic Agents

c.    Surgical and Endovascular Systems for Stroke Prophylaxis

i.    Cerebral Aneurysm/Arteriovenous Malformation Surgical Clipping Systems

ii.    Cerebral Aneurysm/Arteriovenous Malformation Endovascular Embolization Systems

iii.   Carotid Artery Stenting and Associated Distal Embolic Protection Systems

d.   Cerebrovascular Endovascular Systems for Stroke Treatment

i.    Cerebral Embolectomy/Thrombectomy Systems

ii.    Intracranial Stenting Systems

iii.   Cerebral Perfusion Augmentation Systems

ii.    Combined Market Forecast for Selected Current and Emerging Stroke Management Products

iii.   Methodology

 

Exhibit ES-1:    Diagnostic Imaging Systems, Combined Market Forecast, 2006-2012

Exhibit ES-2:    Stroke-Attributable Drug Therapy, Combined Market Forecast, 2006-2012

Exhibit ES-3:    Surgical and Endovascular Stroke Prophylaxis Systems, Combined Market Forecast, 2006-2012

Exhibit ES-4:    Cerebrovascular Endovascular Stroke Treatment Systems, Combined Market Forecast, 2006-2012

Exhibit ES-5:    Stroke Management Products, Combined Market Forecast, 2006-2012

 

1. CLINICAL OVERVIEW

1.1 Etiology

1.1.1 Ischemic versus Hemorrhagic Stroke

1.1.1.1 Ischemic Stroke

1.1.1.1.1 Types of Ischemic Stroke

1.1.1.1.1.1 Thrombotic

1.1.1.1.1.2 Embolic

1.1.1.1.1.3 Hypoperfusion

1.1.1.1.2 Symptoms and Risk Factors

1.1.1.1.3 Diagnostic and Therapeutic Management

1.1.1.1.3.1 Diagnostic Management

1.1.1.1.3.2 Therapeutic Management

1.1.1.1.4 Transient Ischemic Attack

1.1.1.2 Hemorrhagic Stroke

1.1.1.2.1 Intracerebral

1.1.1.2.1.1 Symptoms and Risk Factors

1.1.1.2.1.2 Diagnostic and Therapeutic Management

1.1.1.2.2 Subarachnoid

1.1.1.2.2.1 Symptoms and Risk Factors

1.1.1.2.2.2 Diagnostic and Therapeutic Management

1.2 Stroke Incidence and Prevalence

 

Exhibit 1-1:      The Circle of Willis

Exhibit 1-2:      Clinical Features and Characteristics of Ischemic Stroke

Exhibit 1-3:      Clinical Features and Characteristics of Hemorrhagic Stroke

Exhibit 1-4:      Prevalence of Stroke, by Age and Gender, 1999 to 2004

Exhibit 1-5:      Stroke Incidence, Mortality, and Hospital Discharges

 

2. CLINICAL MANAGEMENT OF STROKE

2.1 Stroke Diagnostics and Diagnostic Imaging

2.1.1 Computed Tomography

2.1.1.1 Spiral Computed Tomography

2.1.1.2 Multislice Computed Tomography

2.1.1.3 Dual-Source Multislice Computed Tomography

2.1.1.4 Computed Tomography Angiography

2.1.1.5 Perfusion Computed Tomography

2.1.1.6 Stroke-Related Applications of Diagnostic Imaging

2.1.1.7 Procedure Volumes Forecast

2.1.2 Magnetic Resonance Imaging

2.1.2.1 Magnetic Resonance Angiography

2.1.2.2 Time-of-Flight Magnetic Resonance Angiography

2.1.2.3 Phase-Contrast Magnetic Resonance Angiography

2.1.2.4 Contrast-Enhanced Magnetic Resonance Angiography

2.1.2.5 Functional Magnetic Resonance Imaging

2.1.2.6 Proton Magnetic Resonance Spectroscopy

2.1.2.7 Stroke-Related Applications of Magnetic Resonance Imaging

2.1.2.8 Procedure Volumes Forecast

2.1.3 Diagnostic Ultrasound

2.1.3.1 Doppler Ultrasound

2.1.3.2 Duplex Ultrasound

2.1.3.3 Stroke-Related Applications of Diagnostic Ultrasound

2.1.3.4 Procedure Volumes Forecast

2.1.4 Cerebral Angiography

2.1.4.1 Stroke-Related Applications of Cerebral Angiography

2.1.4.2 Procedure Volumes Forecast

2.1.5 Nuclear Medicine Imaging

2.1.5.1 Gamma Camera Imaging

2.1.5.2 Positron Emission Tomography

2.1.5.3 Stroke-Related Applications of Nuclear Imaging

2.1.5.4 Procedure Volumes Forecast

2.2 Therapeutic Management of Stroke

2.2.1 Pharmacologic Therapeutic Modalities

2.2.1.1 Anticoagulation Drug Therapy

2.2.1.1.1 Caseload Volumes Forecast

2.2.1.2 Antihypertensive Drug Therapy

2.2.1.2.1 Caseload Volumes Forecast

2.2.1.3 Antiplatelet Drug Therapy

2.2.1.3.1 Caseload Volumes Forecast

2.2.1.4 Oral Anticonvulsive Drug Therapy

2.2.1.4.1 Caseload Volumes Forecast

2.2.1.5 Thrombolytic Drug Therapy

2.2.1.5.1 Caseload Volumes Forecast

2.2.2 Surgical and Endovascular Interventions

2.2.2.1 Carotid Artery Stenosis

2.2.2.1.1 Carotid Endarterectomy

2.2.2.1.1.1 Procedure Volumes Forecast

2.2.2.1.2 Carotid Artery Stenting

2.2.2.1.2.1 Procedure Volumes Forecast

2.2.2.2 Intracranial Aneurysms and Arteriovenous Malformations

2.2.2.2.1 Intracranial Aneurysms

2.2.2.2.1.1 Incidence and Prevalence

2.2.2.2.2 Arteriovenous Malformations

2.2.2.2.2.1 Incidence

2.2.2.2.3 Surgical Repair

2.2.2.2.3.1 Procedure Volumes Forecast

2.2.2.2.4 Endovascular Embolization

2.2.2.2.4.1 Procedure Volumes Forecast

2.2.2.2.5 Stereotactic Radiotherapy

2.2.2.2.5.1 Procedure Volumes Forecast

2.2.2.3 Emerging Device-Based Endovascular Therapies

2.2.2.3.1 Intracranial Stenting Systems

2.2.2.3.2 Cerebral Collateral Flow Enhancement Systems

2.2.2.3.3 Procedure Volumes Forecast

 

Exhibit 2-1:      Computed Tomography, Procedure Volumes Forecast, 2006-2012

Exhibit 2-2:      Magnetic Resonance Imaging, Procedure Volumes Forecast, 2006-2012

Exhibit 2-3:      Ultrasound, Procedure Volumes Forecast, 2006-2012

Exhibit 2-4:      Cerebral Angiography, Procedure Volumes Forecast, 2006-2012

Exhibit 2-5:      Nuclear Imaging, Procedure Volumes Forecast, 2006-2012

Exhibit 2-6:      Oral Anticoagulation Therapy, Caseload Volumes Forecast, 2006-2012

Exhibit 2-7:      Antihypertensive Drug Therapy, Caseload Volumes Forecast, 2006-2012

Exhibit 2-8:      Antiplatelet Drug Therapy, Caseload Volumes Forecast, 2006-2012

Exhibit 2-9:      Oral Anticonvulsive Drug Therapy, Caseload Volumes Forecast, 2006-2012

Exhibit 2-10:    Intravenous Thrombolysis Therapy, Caseload Volumes Forecast, 2006-2012

Exhibit 2-11:    Carotid Endarterectomy, Procedure Volumes Forecast, 2006-2012

Exhibit 2-12:    Protected Carotid Artery Stenting, Procedure Volumes Forecast, 2006-2012

Exhibit 2-13:    Surgical Repair of Cerebral Aneurysms and Arteriovenous Malformations, Procedure Volumes Forecast, 2006-2012

Exhibit 2-14:    Endovascular Embolizations of Cerebral Aneurysms and Arteriovenous Malformations, Procedure Volumes Forecast, 2006-2012

Exhibit 2-15:    Stereotactic Radiotherapy for Cerebral Aneurysm and Arteriovenous Malformations, Procedure Volumes Forecast, 2006-2012

Exhibit 2-16:    Novel Device-Based Cerebral Revascularization/Reperfusion for Acute Stroke and Post-Acute Stroke, Procedure Volumes Forecast, 2006-2012

 

3. STROKE MANAGEMENT PRODUCTS

3.1 Diagnostic Imaging Systems

3.1.1 Computed Tomography Products

3.1.1.1 Market Forecast

3.1.1.2 Competitive Analysis

3.1.2 Magnetic Resonance Imaging Products

3.1.2.1 Market Forecast

3.1.2.2 Competitive Analysis

3.1.3 Diagnostic Ultrasound Products

3.1.3.1 Market Forecast

3.1.3.2 Competitive Analysis

3.1.4 Nuclear Medicine Imaging Products

3.1.4.1 Market Forecast

3.1.4.2 Competitive Analysis

3.1.5 Cerebral Angiography Products

3.1.5.1 Market Forecast

3.1.5.2 Competitive Analysis

3.2 Drug Therapy Products

3.2.1 Oral Anticoagulation Agents

3.2.1.1 Market Forecast

3.2.1.2 Competitive Analysis

3.2.2 Oral Antihypertensive Agents

3.2.2.1 Market Forecast

3.2.2.2 Competitive Analysis

3.2.3 Oral Antiplatelet Agents

3.2.3.1 Market Forecast

3.2.3.2 Competitive Analysis

3.2.4 Oral Anticonvulsant Agents

3.2.4.1 Market Forecast

3.2.4.2 Competitive Analysis

3.2.5 Intravenous Thrombolytic Agents

3.2.5.1 Market Forecast

3.2.5.2 Competitive Analysis

3.3 Surgical and Endovascular Systems for Stroke Prophylaxis

3.3.1 Market Forecast

3.3.2 Cerebral Aneurysm/Arteriovenous Malformation Surgical Clipping Systems

3.3.2.1 Market Forecast

3.3.2.2 Competitive Analysis

3.3.3 Cerebral Aneurysm/Arteriovenous Malformation Endovascular Embolization Systems

3.3.3.1 Market Forecast

3.3.3.2 Competitive Analysis

3.3.4 Carotid Artery Stenting and Associated Distal Embolic Protection Systems

3.3.4.1 Market Forecast

3.3.4.2 Competitive Analysis

3.4 Cerebrovascular Endovascular Systems for Stroke Treatment

3.4.1 Cerebral Embolectomy/Thrombectomy Products

3.4.1.1 Concentric Medical

3.4.1.2 Penumbra

3.4.1.3 Emerging Cerebral Embolectomy/Thrombectomy Systems

3.4.1.3.1 EKOS

3.4.1.3.2 Phenox and ev3

3.4.1.3.3 ImaRx Therapeutics

3.4.1.4 Market Forecast

3.4.2 Intracranial Stenting Systems

3.4.2.1 Boston Scientific

3.4.2.2 Emerging Intracranial Stent Systems

3.4.2.2.1 ev3

3.4.2.2.2 Micrus Endovascular

3.4.2.3 Market Forecast

3.4.3 Cerebral Perfusion Augmentation Systems

3.4.3.1 CoAxia

3.4.3.2 Emerging Cerebral Perfusion Augmentation Systems

3.4.3.3 Market Forecast

 

Exhibit 3-1:      Stroke Management Products, Combined Market Forecast, 2006-2012

Exhibit 3-2:      Diagnostic Imaging, Procedure Volumes Forecast, 2006-2012

Exhibit 3-3:      Diagnostic Imaging, Combined Market Forecast, 2006-2012

Exhibit 3-4:      2008, Selected Computed Tomography Systems

Exhibit 3-5:      Computed Tomography Systems, Market Forecast, 2006-2012

Exhibit 3-6:      2007, Computed Tomography Systems Market, Share by Supplier

Exhibit 3-7:      2008, Selected Magnetic Resonance Imaging Systems

Exhibit 3-8:      Magnetic Resonance Imaging Systems, Market Forecast, 2006-2012

Exhibit 3-9:      2007, Magnetic Resonance Imaging Systems Market, Share by Supplier

Exhibit 3-10:    2008, Selected Diagnostic Ultrasound Systems

Exhibit 3-11:    Diagnostic Ultrasound Systems, Market Forecast, 2006-2012

Exhibit 3-12:    2007, Diagnostic Ultrasound Systems Market, Share by Supplier

Exhibit 3-13:    2008, Selected Nuclear Medicine Imaging Systems

Exhibit 3-14:    Nuclear Medicine Imaging Systems, Market Forecast, 2006-2012

Exhibit 3-15:    2007, Nuclear Medicine Imaging Systems Market, Share by Supplier

Exhibit 3-16:    2008, Selected Cardiac and Surgical X-Ray Systems

Exhibit 3-17:    Cerebral Angiography Imaging Systems and Transcatheter Products, Market Forecast, 2006-2012

Exhibit 3-18:    2007, Cardiac X-Ray Systems Market, Share by Supplier

Exhibit 3-19:    2007, Cerebral Angiography Catheters and Contrast Delivery Devices Market, Share by Supplier

Exhibit 3-20:    Stroke-Attributable Drug Therapy, Combined Caseload Volumes Forecast, 2006-2012

Exhibit 3-21:    Stroke-Attributable Drug Therapy, Combined Market Forecast, 2006-2012

Exhibit 3-22:    Oral Anticoagulation Agents, Market Forecast, 2006-2012

Exhibit 3-23:    2007, Oral Anticoagulation Agents Market, Share by Supplier

Exhibit 3-24:    Oral Antihypertensive Agents, Market Forecast, 2006-2012

Exhibit 3-25:    2007, Oral Antihypertensive Agents Market, Share by Supplier

Exhibit 3-26:    Stroke-Attributable Oral Antiplatelet Agents, Market Forecast, 2006-2012

Exhibit 3-27:    2007, Stroke-Attributable Oral Antiplatelet Agents Market, Share by Supplier

Exhibit 3-28:    Oral Anticonvulsant Agents, Market Forecast, 2006-2012

Exhibit 3-29:    2007, Oral Anticonvulsant Agents Market, Share by Supplier

Exhibit 3-30:    Intravenous Thrombolytic Agents, Market Forecast, 2006-2012

Exhibit 3-31:    2007, Intravenous Thrombolytic Agents Market, Share by Supplier

Exhibit 3-32:    Surgical and Endovascular Stroke Prophylaxis, Combined Procedure Volumes Forecast, 2006-2012

Exhibit 3-33:    Surgical and Endovascular Stroke Prophylaxis Systems, Combined Market Forecast, 2006-2012

Exhibit 3-34:    2008, Selected Cerebral Aneurysm/ Arteriovenous Malformation Surgical Clips

Exhibit 3-35:    Cerebral Aneurysm/Arteriovenous Malformation Surgical Clips, Market Forecast, 2006-2012

Exhibit 3-36:    2007, Cerebral Aneurysm/Arteriovenous Malformation Surgical Clips Market, Share by Supplier

Exhibit 3-37:    2008, Selected Cerebral Aneurysm/Arteriovenous Malformation Endovascular Embolization Systems

Exhibit 3-38:    Cerebral Aneurysm/Arteriovenous Malformation Endovascular Embolization Systems, Market Forecast, 2006-2012

Exhibit 3-39:    2007, Cerebral Aneurysm/Arteriovenous Malformation Endovascular Embolization Systems Market, Share by Supplier

Exhibit 3-40:    2008, Selected Current and Emerging Carotid Artery Stenting and Distal Embolic Protection Systems

Exhibit 3-41:    Carotid Artery Stenting and Associated Distal Embolic Protection Systems, Market Forecast, 2006-2012

Exhibit 3-42:    2007, Carotid Artery Stenting and Associated Distal Embolic Protection Systems Market, Share by Supplier

Exhibit 3-43:    Novel Cerebral Revascularization/Reperfusion, Combined Procedure Volumes Forecast, 2006-2012

Exhibit 3-44:    Cerebrovascular Endovascular Stroke Treatment Systems, Combined Market Forecast, 2006-2012

Exhibit 3-45:    2008, Selected Current and Emerging Cerebral Embolectomy/Thrombectomy Systems

Exhibit 3-46:    Cerebral Embolectomy/Thrombectomy Systems, Market Forecast, 2006-2012

Exhibit 3-47:    2008, Selected Current and Emerging Intracranial Stenting Systems

Exhibit 3-48:    Intracranial Stenting Systems, Market Forecast, 2006-2012

Exhibit 3-49:    2008, Selected Current and Emerging Cerebral Perfusion Augmentation Systems

Exhibit 3-50:    Cerebral Perfusion Augmentation Systems, Market Forecast, 2006-2012

 

4. COMPANY PROFILES

4.1       Abbott Laboratories

4.2       Barr Pharmaceuticals, Inc.

4.3       B. Braun Melsungen AG

4.4       Boston Scientific Corporation

4.5       Bristol-Myers Squibb Company

4.6       CoAxia, Inc.

4.7       Concentric Medical, Inc.

4.8       ev3, Inc.

4.9       Genentech, Inc.

4.10     General Electric Company

4.11     GlaxoSmithKline PLC

4.12     Johnson & Johnson

4.13     Merck & Company, Inc.

4.14     Micrus Endovascular Corporation

4.15     Mizuho Ikakogyo Co. LTD

4.16     Novartis AG

4.17     Pfizer, Inc.

4.18     Royal Philips Electronics NV

4.19     Siemens AG

 

APPENDIX:  COMPANY LISTING

 

 

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