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European Markets for Percutaneous Transluminal Coronary Angioplasty and Coronary Stenting Products
Report #A244 - August 2010
373 Pages – 89 Exhibits - 17 Company Profiles


Coronary heart disease (CHD) is responsible for more than 1.9 million deaths in Europe each year, accounting for 21.0% of deaths in men and 22.2% of deaths in women. In the 27 member countries comprising the European Union (EU), CHD accounts for approximately 741,833 deaths annually, with 16.0% and 14.8% of deaths in men and women attributable to the disease, respectively. The morbidity and mortality rates associated with CHD continue to fuel the demand for percutaneous transluminal coronary angioplasty (PTCA) and coronary stenting products—particularly drug-eluting stents—to treat advanced cases that cannot be adequately managed with lifestyle changes or aggressive medical therapy.

Approximately 800,000 PTCA and/or coronary stenting procedures were performed in Europe in 2009, generating nearly $1.9 billion in corresponding product sales. It is expected that during the forecast period, sales of PTCA and coronary stenting products will increase at a compound annual rate of 5.1%, reaching an estimated $2.4 billion in the year 2014.

This dynamic, new report from Medtech Insight includes analyses of products, current and forecast markets, competitors, and opportunities for suppliers of PTCA and coronary stenting products in Europe.

Covered topics in this report include bare-metal and drug-eluting stent systems; conventional and drug-eluting balloon angioplasty procedures; conventional balloon angioplasty catheters; coronary stenting procedures; drug-eluting balloon angioplasty catheters; guidewires; guiding catheters; national healthcare systems in France, Germany, Italy, Spain, the United Kingdom and the Benelux countries of Belgium, Luxembourg, and the Netherlands; European heart disease and population statistics; introducers/sheaths; inflation devices; stent coatings and surfaces and anti-restenosis agents; stent configurations and materials; technological developments in coronary angioplasty and stenting; and vascular access site closure devices.

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European Markets for Percutaneous Transluminal Coronary Angioplasty and Coronary Stenting Products

A244

August 2010

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Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

 

EXECUTIVE SUMMARY

i.       Percutaneous Transluminal Coronary Angioplasty Devices Market

a.      Products

i.       Balloon Angioplasty Catheters

ii.       Guiding Catheters

iii.      Guidewires

iv.      Introducers/Sheaths

v.      Inflation Devices

vi.      Vascular Access Site Closure Devices

b.      Market Forecast

ii.          Coronary Stenting Systems Market

a.      Products

b.      Market Forecast

iii.         Methodology

 

Exhibit ES-1:    Europe, Percutaneous Transluminal Coronary Angioplasty and Coronary Stenting, Procedure Volumes Forecast, by Country, 2009-2014

Exhibit ES-2:    Europe, Percutaneous Transluminal Coronary Angioplasty and Coronary Stenting Systems, Market Forecast, by Country, 2009-2014

Exhibit ES-3:    Europe, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit ES-4:    France, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit ES-5:    Germany, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit ES-6:    Italy, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit ES-7:    Spain, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit ES-8:    United Kingdom, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit ES-9:    Benelux Countries, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit ES-10:  Europe, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit ES-11:  France, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit ES-12:  Germany, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit ES-13:  Italy, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit ES-14:  Spain, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit ES-15:  United Kingdom, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit ES-16:  Benelux Countries, Coronary Stents, Combined Market Forecast, 2009-2014

 

1. EUROPEAN HEALTHCARE MARKETS

1.1 The European Union

1.1.1 A Common Currency

1.1.2 Regulatory Policies

1.1.3 Reimbursement

1.1.4 Healthcare Spending

1.2 Selected European National Healthcare Profiles

1.2.1 France

1.2.1.1 Healthcare Organization and Reform

1.2.1.2 Hospital Services

1.2.1.3 Medical Device Reimbursement

1.2.2 Germany

1.2.2.1 Healthcare Organization and Reform

1.2.2.2 Hospital Services

1.2.2.3 Medical Device Reimbursement

1.2.3 Italy

1.2.3.1 Healthcare Organization and Reform

1.2.3.2 Hospital Services

1.2.3.3 Medical Device Reimbursement

1.2.4 Spain

1.2.4.1 Healthcare Organization and Reform

1.2.4.2 Hospital Services

1.2.4.3 Medical Device Reimbursement

1.2.5 United Kingdom

1.2.5.1 Healthcare Organization and Reform

1.2.5.2 Hospital Services

1.2.5.3 Medical Device Reimbursement

1.2.6 Benelux

1.2.6.1 Healthcare Organization and Reform

1.2.6.1.1 Belgium

1.2.6.1.2 Luxembourg

1.2.6.1.3 The Netherlands

1.2.6.2 Hospital Services

1.2.6.3 Medical Device Reimbursement

 

Exhibit 1-1:      European Union, Medical Devices Risk Classification System

Exhibit 1-2:      European Union Population Statistics Comparison for the Years 1999, 2009, and 2019

Exhibit 1-3:      France, Selected National Healthcare Statistics

Exhibit 1-4:      Germany, Selected National Healthcare Statistics

Exhibit 1-5:      Italy, Selected National Healthcare Statistics

Exhibit 1-6:      Spain, Selected National Healthcare Statistics

Exhibit 1-7:      United Kingdom, Selected National Healthcare Statistics

Exhibit 1-8:      Belgium, Selected National Healthcare Statistics

Exhibit 1-9:      Luxembourg, Selected National Healthcare Statistics

Exhibit 1-10:    The Netherlands, Selected National Healthcare Statistics

 

2. OVERVIEW OF SELECTED CARDIOVASCULAR DISEASES/DISORDERS

2.1 The Heart and Circulatory System

2.1.1 The Cardiac Conduction Sytem

2.1.2 The Heart Valves

2.2 Diseases/Disorders Involving the Vasculature

2.2.1 Coronary Heart Disease

2.2.1.1 Atherosclerosis

2.2.1.1.1 Description

2.2.1.1.2 Statistics

2.2.1.2 Angina Pectoris

2.2.1.2.1 Description

2.2.1.2.2 Statistics

2.2.1.3 Myocardial Infarction

2.2.1.3.1 Description

2.2.1.3.2 Statistics

2.2.2 Hypertension

2.2.2.1 Description

2.2.2.1.1 Systolic and Diastolic Pressures

2.2.2.1.2 Prehypertension

2.2.2.2 Statistics

2.2.3 Aneurysm

2.2.3.1 Description

2.2.3.2 Statistics

2.2.4 Stroke

2.2.4.1 Description

2.2.4.2 Statistics

2.3 Diseases/Disorders Involving the Cardiac Conduction System

2.3.1 Types

2.3.1.1 Bradycardia

2.3.1.1.1 Description

2.3.1.2 Sick Sinus Syndrome

2.3.1.2.1 Description

2.3.1.3 Heart Block

2.3.1.3.1 Description

2.3.1.4 Atrial Fibrillation

2.3.1.4.1 Description

2.3.1.5 Tachycardia

2.3.1.5.1 Description

2.3.1.6 Ventricular Fibrillation

2.3.1.6.1 Description

2.3.2 Statistics

2.4 Diseases/Disorders Involving the Myocardium

2.4.1 Heart Defects

2.4.1.1 Description

2.4.1.2 Statistics

2.4.2 Heart Failure

2.4.2.1 Description

2.4.2.2 Statistics

2.4.3 Rheumatic Fever/Rheumatic Heart Disease

2.4.3.1 Description

2.4.3.2 Statistics

2.4.4 Heart Valve Disorders

2.4.4.1 Types

2.4.4.1.1 Valvular Stenosis

2.4.4.1.1.1 Description

2.4.4.1.2 Valvular Regurgitation

2.4.4.1.2.1 Description

2.4.4.1.3 Valve Prolapse

2.4.4.1.3.1 Description

2.4.4.2 Statistics

 

Exhibit 2-1:      Cross-Section Diagram of the Heart

Exhibit 2-2:      Cross-Section Diagram of the Heart Valves

Exhibit 2-3:      Men, Number of Deaths due to Cardiovascular Disease, Selected European Countries

Exhibit 2-4:      Women, Number of Deaths due to Cardiovascular Disease, Selected European Countries

Exhibit 2-5:      Total Cholesterol Levels in Men, Selected European Countries, 2005 and 2010

Exhibit 2-6:      Total Cholesterol Levels in Women, Selected European Countries, 2005 and 2010

Exhibit 2-7:      Europe, Atherosclerosis Prevalence, by Country

Exhibit 2-8:      Standard Angina Pectoris Classification

Exhibit 2-9:      Europe, Coronary Events Incidence Rates, Selected MONICA Project Populations, by Gender Group

Exhibit 2-10:    Europe, Myocardial Infarction Prevalence, by Country

Exhibit 2-11:    Europe, Systolic Blood Pressure Levels, Selected MONICA Project Populations, by Gender Group

Exhibit 2-12:    Mean Systolic Blood Pressure Levels in Men, Selected European Countries, 2005 and 2010

Exhibit 2-13:    Mean Systolic Blood Pressure Levels in Women, Selected European Countries 2005 and 2010

Exhibit 2-14:    Europe, Hypertension Prevalence, by Country

Exhibit 2-15:    Europe, Aneurysm Prevalence, by Country

Exhibit 2-16:    Europe, Stroke Disability and Mortality, By Country

Exhibit 2-17:    Europe, Stroke Prevalence, by Country

Exhibit 2-18:    Europe, Cardiac Dysrhythmia Prevalence, by Country

Exhibit 2-19:    Congenital Heart Defects, Estimated Number of Simple and Complex Cases in the United Kingdom, 2000 and 2010

Exhibit 2-20:    United Kingdom, Heart Failure Prevalence, Selected Study Data

Exhibit 2-21:    Europe, Heart Failure Prevalence, by Country

Exhibit 2-22:    Rheumatic Heart Disease, Estimated Number of Reported Cases, Selected Countries/Regions

Exhibit 2-23:    Rheumatic Heart Disease Mortality, Selected European Countries

Exhibit 2-24:    Euro Heart Survey on Valvular Heart Disease Patient Population, Native Heart Valve Disorders, by Type

Exhibit 2-25:    Europe, Heart Valve Disorder Prevalence, by Country

 

3. PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY PRODUCTS MARKET

3.1 Percutaneous Transluminal Coronary Angioplasty

3.1.1 Approaches

3.1.2 Indications

3.1.3 Complications/Efficacy

3.1.4 Adjunctive Anti-Clotting Drug Therapies

3.1.5 Conventional versus Drug-Eluting Balloon Angioplasty

3.1.6 Products

3.1.6.1 Balloon Angioplasty Catheters

3.1.6.1.1 Conventional

3.1.6.1.2 Drug-Eluting

3.1.6.2 Guiding Catheters

3.1.6.3 Guidewires

3.1.6.4 Introducers/Sheaths

3.1.6.5 Inflation Devices

3.1.6.6 Vascular Access Site Closure Devices

3.1.7 Procedure Volumes

3.1.8 Market Forecast

3.1.9 Competitors

 

Exhibit 3-1:      2010, Selected Percutaneous Transluminal Coronary Angioplasty Balloon Catheters

Exhibit 3-2:      2010, Selected Guiding Catheters

Exhibit 3-3:      2010, Selected Guidewires

Exhibit 3-4:      2010, Selected Introducers/Sheaths

Exhibit 3-5:      2010, Selected Inflation Devices

Exhibit 3-6:      2010, Selected Vascular Access Site Closure Devices

Exhibit 3-7:      Europe, Percutaneous Transluminal Coronary Angioplasty/Coronary Stenting, Procedure Volumes Forecast, 2009-2014

Exhibit 3-8:      France, Percutaneous Transluminal Coronary Angioplasty/ Coronary Stenting, Procedure Volumes Forecast,  2009-2014

Exhibit 3-9:      Germany, Percutaneous Transluminal Coronary Angioplasty/ Coronary Stenting, Procedure Volumes Forecast,  2009-2014

Exhibit 3-10:    Italy, Percutaneous Transluminal Coronary Angioplasty/ Coronary Stenting, Procedure Volumes Forecast,  2009-2014

Exhibit 3-11:    Spain, Percutaneous Transluminal Coronary Angioplasty/ Coronary Stenting, Procedure Volumes Forecast,  2009-2014

Exhibit 3-12:    United Kingdom, Percutaneous Transluminal Coronary Angioplasty/Coronary Stenting, Procedure Volumes Forecast, 2009-2014

Exhibit 3-13:    Benelux Countries, Percutaneous Transluminal Coronary Angioplasty/Coronary Stenting, Procedure Volumes Forecast, 2009-2014

Exhibit 3-14:    Europe, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit 3-15:    France, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit 3-16:    Germany, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit 3-17:    Italy, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit 3-18:    Spain, Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2009-2014

Exhibit 3-19:    United Kingdom, Percutaneous Transluminal Coronary Angioplasty Devices,  Market Forecast, 2009-2014

Exhibit 3-20:    Benelux Countries, Percutaneous Transluminal Coronary Angioplasty Devices,  Market Forecast, 2009-2014

Exhibit 3-21:    2009, Percutaneous Transluminal Coronary Angioplasty Devices Market, Share by Supplier

 

4. CORONOARY STENT SYSTEMS MARKET

4.1 Coronary Stenting with Bare-Metal and Drug-Eluting Stents

4.1.1 Stent Materials

4.1.1.1 Cobalt-Based Alloys

4.1.1.2 Nitinol

4.1.1.3 Stainless Steel

4.1.1.4 Tantalum

4.1.1.5 Bioabsorbable Polymers and Metal-Based Alloys

4.1.2 Stent Coatings/Surfaces and Anti-Restenosis Agents

4.1.3 Stent Delivery/Deployment

4.1.4 Indications

4.1.4.1 Left Main Coronary Artery Disease

4.1.4.2 Multivessel Coronary Artery Disease

4.1.5 Complications/Efficacy

4.1.5.1 Repeat Revascularization

4.1.5.2 Stent Thrombosis

4.1.5.3 Diabetes and Stenting

4.1.5.4 Stenting-Associated ST-Segment Elevation Myocardial Infarction

4.1.6 Products

4.1.7 Procedure Volumes

4.1.8 Market Forecast

4.1.9 Competitors

 

Exhibit 4-1:      2010, Selected Anti-Restenosis Agents

Exhibit 4-2:      2010, Selected Coronary Stents

Exhibit 4-3:      Europe, Coronary Stenting, Combined Procedure Volumes Forecast, 2009-2014

Exhibit 4-4:      France, Coronary Stenting, Combined Procedure Volumes Forecast, 2009-2014

Exhibit 4-5:      Germany, Coronary Stenting, Combined Procedure Volumes Forecast, 2009-2014

Exhibit 4-6:      Italy, Coronary Stenting, Combined Procedure Volumes Forecast, 2009-2014

Exhibit 4-7:      Spain, Coronary Stenting, Combined Procedure Volumes Forecast, 2009-2014

Exhibit 4-8:      United Kingdom, Coronary Stenting, Combined Procedure Volumes Forecast, 2009-2014

Exhibit 4-9:      Benelux Countries, Coronary Stenting, Combined Procedure Volumes Forecast, 2009-2014

Exhibit 4-10:    Europe, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit 4-11:    France, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit 4-12:    Germany, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit 4-13:    Italy, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit 4-14:    Spain, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit 4-15:    United Kingdom, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit 4-16:    Benelux Countries, Coronary Stents, Combined Market Forecast, 2009-2014

Exhibit 4-17:    2009, Europe, Coronary Stent Systems Market, Share by Supplier

 

5. COMPANY PROFILES

5.1       Abbott Laboratories

5.2       B. Braun Melsungen AG

5.3       Biosensors International Group LTD

5.4       BIOTRONIK SE & Co, KG

5.5       Boston Scientific Corporation

5.6       Carbostent & Implantable Devices SRL

5.7       ClearStream Technologies Group PLC

5.8       Cook Group, Inc.

5.9       Cordis Corporation/Johnson & Johnson

5.10     eucatech AG

5.11     Hexacath

5.12     InSitu Technologies, Inc.

5.13     Medtronic, Inc.

5.14     Merit Medical Systems, Inc.

5.15     OrbusNeich

5.16     St. Jude Medical, Inc.

5.17     Terumo Medical Corporation/Terumo Corporation

 

APPENDIX:  COMPANY LISTING

 

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