EXECUTIVE
SUMMARY
i. Clinical
Overview
ii. Joint
Replacement and Reconstruction Products
iii. Joint
Replacements, Procedure Volumes Forecast
iv. Joint
Replacements, Combined Market Analysis
v. Methodology
Exhibit ES-1: Total
Joint Arthroplasty, Procedure Volumes Forecast, 2010-2015
Exhibit ES-2: Joint
Replacement/Reconstruction Products, Combined Market Forecast, 2010-2015
1. CLINICAL OVERVIEW OF BONES AND JOINTS
1.1
Bone Structure and Function
1.1.1 Cellular Framework
1.1.1.1 Osteoblasts
1.1.1.2 Osteogenesis
1.1.1.3 Osteocytes
1.1.1.4 Osteoclasts
1.1.2 Collagen
1.1.3 Bone Marrow
1.2
Ligaments and Tendons
1.3
Joint Structure and Function
1.3.1 Knee
1.3.2 Hip
1.3.3 Extremities/Small Bones
1.3.3.1 Shoulder
1.3.3.2 Elbow
1.3.3.3 Hand and Wrist
1.3.3.4 Foot and Ankle
Exhibit 1-1: Classification
of Bone According to Anatomy
Exhibit 1-2: Structure
of Bone
Exhibit 1-3: Structure
of Hydroxyapatite
Exhibit 1-4: Structure
of Collagen
Exhibit 1-5: Anatomy
of the Knee
Exhibit 1-6: Anatomy
of the Hip
Exhibit 1-7: Anatomy
of the Shoulder: The Rotator Cuff
Exhibit 1-8: Anatomy
of the Shoulder: The Glenoid Cavity
Exhibit 1-9: Anatomy
of the Elbow
2.
JOINT REPLACEMENT AND RECONSTRUCTION PRODUCTS MARKET
2.1.
Hip Arthroplasty/Arthroscopy
2.1.1 Primary Hip
Arthroplasty/Total Hip Replacement
2.1.2 Revision Hip Arthroplasty
2.1.3 Hemiarthroplasty
2.1.4 Minimally
Invasive Hip Arthroplasty
2.1.4.1 Anterior Hip Replacement Surgery
2.1.5 Hip Resurfacing
2.1.6 Navigation Systems
2.1.7 Hip Arthroscopy
2.2
Hip Implants
2.2.1 Modular versus
Nonmodular
2.2.2 Cemented
versus Press-Fit
2.2.3 Bearing Surfaces
2.2.3.1 Metal-on-Polyethylene
2.2.3.2 Ceramic-on-Ceramic
2.2.3.3 Metal-on-Metal
2.2.4 Bipolar
Implants
2.2.5 Gender-Specific
Hip Implants
2.2.6 Products
2.2.7 Market
Analysis
2.2.8 Competitive
Analysis
2.3
Knee Implants
2.3.1 Treatment
Options
2.3.1.1 Knee Arthroplasty
2.3.2 Navigation
Systems
2.3.3 Minimally
Invasive Surgery
2.3.4 Robotic Knee
Surgery
2.3.5 Implant
Designs
2.3.5.1 Fixed Bearing
2.3.5.2 Mobile Bearing
2.3.5.3 Medial Pivot
2.3.5.4 Unicompartmental
2.3.5.5 Gender-Specific
2.3.5.6 Patient-Specific/Customized
2.3.6 Products
2.3.7 Market
Analysis
2.3.8 Competitive
Analysis
2.4
Shoulder Implants
2.4.1 Types of
Shoulder Joint Replacement/Resurfacing Procedures
2.4.1.1 Shoulder
Arthroplasty
2.4.1.2 Shoulder
Hemiarthroplasty
2.4.1.3 Shoulder
Resurfacing/Partial Shoulder Replacement
2.4.1.4 Reverse
Shoulder Arthroplasty
2.4.2 Products
2.4.3 Market
Analysis
2.4.4 Competitive
Analysis
2.5
Small Joint Implants
2.5.1 Products
2.5.2 Market
Analysis
2.5.3 Competitive
Analysis
2.6
Joint Replacements, Procedure Volumes Forecast
2.7
Joint Replacements, Combined Market Analysis
2.7.1 Market
Forecast
2.7.2 Affordable
Care Act
2.7.3 Medicare and
Third-Party Payers
2.7.4 Orthopedic
Surgeon Consulting Fees
2.7.5 Payment
Bundling
Exhibit 2-1: A Normal Hip Compared with an Arthritic Hip
Exhibit 2-2: Steps
Involved in Total Hip Arthroplasty
Exhibit 2-3: Hip
Implants, Single-Piece versus Modular Components
Exhibit 2-4: Hip
Implants, Cemented versus Cementless
Exhibit 2-5: Hip
Implant Head/Acetabular Component Combinations and Volumetric Wear Rates
Exhibit 2-6: Differences
in Femoral Head Geometry in Men and Women
Exhibit 2-7: Selected
Primary Hip Stems
Exhibit 2-8: 2011,
Selected Hip Implant Products, Primary Stems
Exhibit 2-9: Selected
Primary Acetabular Components
Exhibit 2-10: 2011,
Selected Primary Acetabular Component Products
Exhibit 2-11: Selected
Revision Hip Stems
Exhibit 2-12: 2011,
Selected Revision Hip Implants
Exhibit 2-13: Selected
Revision Acetabular Components
Exhibit 2-14: 2011,
Selected Revision Acetabular Component Products
Exhibit 2-15: Selected
Femoral Heads
Exhibit 2-16: 2011,
Selected Femoral Head Products
Exhibit 2-17: 2011,
Selected Hip Resurfacing Products
Exhibit 2-18: Primary
Hip Implants, Market Forecast, 2010-2015
Exhibit 2-19: Revision
Hip Implants, Market Forecast, 2010-2015
Exhibit 2-20: 2010,
Hip Implants Market, Share by Supplier
Exhibit 2-21: Basic
Knee Function
Exhibit 2-22: Knee
Implant Components
Exhibit 2-23: Gender-Based
Differences in Knee Implant Designs
Exhibit 2-24: Selected
Knee Implants
Exhibit 2-25: 2011,
Selected Knee Implant Products
Exhibit 2-26: Primary
Knee Implants, Market Forecast, 2010-2015
Exhibit 2-27: Revision
Knee Implants, Market Forecast, 2010-2015
Exhibit 2-28: 2010,
Knee Implants Market, Share by Supplier
Exhibit 2-29: Shoulder
Anatomy, Shoulder Implant Components
Exhibit 2-30: 2011,
Selected Shoulder Implant Products
Exhibit 2-31: Shoulder
Implants, Market Forecast, 2010-2015
Exhibit 2-32: 2010,
Shoulder Implants Market, Share by Supplier
Exhibit 2-33: Indications
for Arthroplasty of the Hand and Wrist
Exhibit 2-34: Selected
Small Joint Implants
Exhibit 2-35: 2011,
Selected Small Joint Implant Products
Exhibit 2-36: Small
Joint Implants, Market Forecast, 2010-2015
Exhibit 2-37: 2010,
Small Joint Implants Market, Share by Supplier
Exhibit 2-38: Total
Joint Arthroplasty, Procedure Volumes Forecast, 2010-2015
Exhibit 2-39: Joint
Replacement/Reconstruction Products, Combined Market Forecast, 2010-2015
3.
COMPANY PROFILES
3.1 Biomet,
Inc.
3.2 ConforMIS,
Inc.
3.3 DePuy
Orthopaedics, Inc./Johnson & Johnson
3.4 Exactech,
Inc.
3.5 Integra
LifeSciences Corporation
3.6 Smith
& Nephew PLC
3.7 Stryker
Corporation
3.8 Tornier,
Inc.
3.9 Wright
Medical Group, Inc.
3.10 Zimmer
Holdings, Inc.
APPENDIX: COMPANY
LISTING