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European Markets for Spinal Motion-Preserving Devices
Report #A318
- February 2014
171 Pages – 43 Exhibits


An estimated 34 million people in the 5 major European Union markets (France, Germany, Italy, Spain, and the United Kingdom) and the Benelux and Nordic regions suffer from chronic back pain, and the incidence is expected to increase over the next several years, largely due to an expanding elderly population and the growing incidence of degenerative disc disease.

This dynamic new report from Medtech Insight includes analyses of products, current/forecast markets, competitors, and opportunities in the European market for nonfusion spinal technologies for the treatment of degenerative disc disease. Product areas covered by the scope of this report include artificial discs, dynamic stabilization systems (facet replacements, interspinous process spacers, and pedicle screws), kyphoplasty and vertebroplasty systems, nucleus replacements, and percutaneous intradiscal electrotherapy and plasma disc decompression devices.

During the forecast period covered by this report, the combined European market for spinal motion-preserving devices is projected to increase at a compound annual rate of 5.4%, reaching an estimated $524.8 million in the year 2017. The segment that is projected to experience the greatest growth is represented by sales of artificial discs, followed by dynamic stabilization systems and vertebral compression fracture repair products, with disc altering systems experiencing modest growth over the next half-decade. The European market for nucleus replacement devices for degenerative disc disease has declined in recent years.

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European Markets for Spinal Motion-Preserving Devices

A318

February 2014

$4,850

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Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

 

EXECUTIVE SUMMARY

i.          Artificial Discs

ii.          Dynamic Stabilization

iii.         Vertebral Compression Fracture Products

iv.         Disc Altering Products

v.         Methodology

 

1. CLINICAL OVERVIEW OF DEGENERATIVE SPINAL DISORDERS

1.1 Anatomy of the Human Spine

1.1.1 Vertebrae

1.1.2 Intervertebral Discs

1.1.3 Spinal Cord

1.2 Bone Physiology and Remodeling

1.3 Degenerative Disorders

1.3.1 Degenerative Disc Disease

1.3.2 Herniated Disc

1.3.3 Spinal Stenosis

1.3.4 Spondylosis

1.3.5 Spondylolisthesis

1.3.6 Osteoporosis

1.3.7 Rheumatoid Arthritis

1.3.8 Paget’s Disease

 

Exhibit 1-1:      The Human Spine

Exhibit 1-2:      A Segment of the Spinal Column

Exhibit 1-3:      A Simple Illustrated Diagram of a Spinal Disc

Exhibit 1-4:      Common Degenerative Spinal Disorders

Exhibit 1-5:      Stages of a Disc Herniation

Exhibit 1-6:      A Healthy Cervical Spine in Comparison to Spinal Stenosis and Herniation

Exhibit 1-7:      A Simple Illustrated Diagram of Spondylolisthesis in the Spine

Exhibit 1-8:      A Simple Illustrated Diagram of a Vertebral Compression Fracture

 

2. TOTAL DISC REPLACEMENT

2.1 Materials and Designs

2.2 Artificial Cervical Discs

2.2.1 Selected Clinical Evidence Regarding Artificial Cervical Discs

2.2.1.1 The Bryan Disc

2.2.1.2 The Mobi-C Disc

2.2.1.3 The Prestige Disc

2.2.1.4 The ProDisc-C Disc

2.2.1.5 The SECURE-C Disc

2.3 Artificial Lumbar Discs

2.3.1 Products

2.3.1.1 AxioMed Spine

2.3.1.2 B. Braun Melsungen

2.3.1.3 DePuy Synthes/Johnson & Johnson

2.3.1.4 Globus Medical

2.3.1.5 LDR

2.3.1.6 Ranier Technology

2.3.1.7 Spinal Kinetics

2.3.2 Pipeline Products No Longer Under Development

2.4 Market Analysis

2.4.1 Artificial Cervical Discs

2.4.2 Artificial Lumbar Discs

2.5 Competitive Analysis

2.5.1 Artificial Cervical Discs

2.5.2 Artificial Lumbar Discs

 

Exhibit 2-1:      Differentiating Features of Artificial Disc Designs

Exhibit 2-2:      Important Mechanical Properties of Artificial Discs

Exhibit 2-3:      2014, Selected Artificial Cervical Discs

Exhibit 2-4:      2014, Selected Artificial Lumbar Discs

Exhibit 2-5:      Comparison of Second-Generation Artificial Lumbar Disc Technology with First-Generation Technology

Exhibit 2-6:      Europe, Artificial Discs, Combined Market Forecast, by Country, 2012-2017

Exhibit 2-7:      Europe, Artificial Cervical Discs, Market Forecast, by Country, 2012-2017

Exhibit 2-8:      Europe, Artificial Lumbar Discs, Market Forecast, by Country, 2012-2017

Exhibit 2-9:      2012, Europe, Artificial Cervical Discs Market, Share by Supplier

Exhibit 2-10:    2012, Europe, Artificial Lumbar Discs Market, Share by Supplier

 

3. DISC NUCLEUS REPLACEMENT TECHNOLOGIES

3.1 Product Development Programs

3.2 Abandoned Pipeline Products

3.3 Market Analysis

 

Exhibit 3-1:      The Prosthetic Disc Nucleus

Exhibit 3-2:      The NeuDisc

Exhibit 3-3:      The Percutaneous Nucleus Replacement

 

4. DYNAMIC STABILIZATION DEVICES

4.1 Types of Devices

4.1.1 Interspinous Process Spacers

4.1.2 Pedicle Screw Dynamic Stabilization Systems

4.1.3 Facet Replacements

4.2 Indications

4.3 Products

4.3.1 Interspinous Process Spacers

4.3.1.1 Scient'x/Alphatec Spine

4.3.1.2 Biomet

4.3.1.3 DePuy Synthes/Johnson & Johnson

4.3.1.4 Globus Medical

4.3.1.5 Medtronic

4.3.1.6 Paradigm Spine

4.3.1.7 Simpirica Spine

4.3.1.8 Vertiflex

4.3.1.9 Zimmer

4.3.2 Pedicle Screw-Based Dynamic Stabilization Systems

4.3.2.1 DePuy Synthes/Johnson & Johnson

4.3.2.2 Globus Medical

4.3.2.3 Mekanika

4.3.2.4 Paradigm Spine

4.3.2.5 Scient’x/Alphatec Spine

4.3.2.6 SpineVision

4.3.2.7 Zimmer

4.3.3 Facet Replacement

4.3.3.1 Globus Medical

4.3.3.2 Premia Spine

4.3.3.3 Zyga Technology

4.4 Market Analysis

4.5 Competitive Analysis

 

Exhibit 4-1:      Anatomic Changes Achieved by Dynamic Stabilization Devices

Exhibit 4-2:      2014, Selected Interspinous Process Spacers

Exhibit 4-3:      2014, Selected Pedicle Screw-Based Dynamic Stabilization Systems

Exhibit 4-4:      2014, Selected Facet Replacement Products

Exhibit 4-5:      Europe, Dynamic Stabilization Products, Market Forecast, By Country, 2012-2017

Exhibit 4-6:      2012, Dynamic Stabilization Products Market, Share by Supplier

 

5. VERTEBRAL COMPRESSION FRACTURE PRODUCTS

5.1 Vertebroplasty

5.1.1 Polymethylmethacrylate Alternatives

5.1.2 Products

5.2 Kyphoplasty/Balloon-Assisted Vertebral Augmentation Systems

5.2.1 Products

5.3 Other Vertebral Augmentation Systems

5.4 Market Analysis

5.4.1 Vertebroplasty

5.4.2 Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems

5.5 Competitive Analysis

5.5.1 Vertebroplasty

5.5.2 Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems

 

Exhibit 5-1:      The Vertebroplasty Procedure

Exhibit 5-2:      Vertebroplasty Indications and Contraindications

Exhibit 5-3:      2014, Selected Vertebroplasty Systems

Exhibit 5-4:      The Balloon Kyphoplasty Procedure

Exhibit 5-5:      Kyphoplasty, Selected Advantages and Disadvantages

Exhibit 5-6:      2014, Selected Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems

Exhibit 5-7:      2014, Selected Alternative Vertebral Augmentation Systems

Exhibit 5-8:      Europe, Vertebroplasty Systems, Market Forecast, by Country, 2012-2017

Exhibit 5-9:      Europe, Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems, Market Forecast, by Country, 2012-2017

Exhibit 5-10:    2012, Europe, Vertebroplasty Systems Market, Share by Supplier

Exhibit 5-11:    2012, Europe, Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems Market, Share by Supplier

 

6. DISC ALTERING PRODUCTS

6.1 Intradiscal Electrothermal Therapy

6.1.1 Clinical Evidence

6.1.2 Practice Guidelines

6.1.3 Products

6.2 Plasma Disc Decompression

6.2.1 Clinical Evidence

6.2.2 Practice Guidelines

6.3 Emerging Technology

6.4 Market Analysis

6.5 Competitive Analysis

 

Exhibit 6-1:      The SpineCath Intradiscal Catheter

Exhibit 6-2:      The Plasma Disc Decompression Procedure

Exhibit 6-3:      Europe, Disc Altering Products, Market Forecast, 2012-2017

Exhibit 6-4:      Europe, Disc Altering Products, Market Forecast, by Country, 2012-2017

Exhibit 6-5:      2012, Europe, Disc Altering Products Market, Share by Supplier

 

APPENDIX:  COMPANY LISTING

 

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