Search
The Newsletter
The Principals
Reports
Conferences
Databases
Custom Research
Contact Us
Home
 

Online Report Subscribers, Click Here

Pricing and Ordering Information

 

U.S. Markets for Orthopedic Biomaterials for Bone Repair and Regeneration
Report #A321
- May 2013
180 Pages – 49 Exhibits – 11 Company Profiles


In the United States (U.S.), more than 430,000 spinal fusions are performed each year, and approximately 20% of the more than 5 million fractures that occur are associated with healing difficulties.

This dynamic new report from Medtech Insight includes analyses of products, competitors, and opportunities in the U.S. market for biomaterial products for bone healing/regeneration and spinal fusion indications. This market, as covered by the scope of this report, includes bioresorbable fixation devices (pins, screws, tacks, suture anchors, and meniscal repair devices); allografts and bone replacement materials (base tissue, demineralized bone matrix, machined bone allografts, and synthetic bone grafts), and osteobiologics (autologous therapy/platelet concentrate systems, gene therapy, platelet-derived growth factors, recombinant human bone morphogenetic proteins, small molecule therapies, and stem cells). During the forecast period covered by this report, the combined U.S. market for orthopedic biomaterials for bone repair and regeneration is projected to reach an estimated value of $3.5 billion in the year 2017.

This is the first of two Medtech Insight reports covering the U.S. market for orthopedic biomaterials. Report #A322, "U.S. Markets for Orthopedic Biomaterials for Viscosupplementation and Cartilage, Ligament, and Tendon Repair and Regeneration," will be published in June 2013.

Ordering Information

Title

Report# Publication
Date
List Price

U.S. Markets for Orthopedic Biomaterials for Bone Repair and Regeneration

A321

May 2013

$3,750

Order Online:
Single User only (Please call for corporate subscription pricing)
PDF Only

Print versions of Reports are available upon request for an additional fee.

Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

 

EXECUTIVE SUMMARY

i.       Bioresorbable Fixation Devices

ii.       Bone Allograft and Synthetic Bone Graft Products

iii.      Osteobiologics

iv.      Combined Market Forecast

v.      Methodology

 

Exhibit ES-1:    Types of Bioresorbable Fixation Devices

Exhibit ES-2:    Bioresorbable Fixation Devices, Market Forecast, 2012-2017

Exhibit ES-3:    Bone Allografts and Synthetic Bone Graft Substitutes, Market Forecast, 2012-2017

Exhibit ES-4:    2012, Bone Allografts and Synthetic Bone Graft Substitutes Market, Share by Tissue Type

Exhibit ES-5:    Recombinant Human Bone Morphogenetic Protein Products, Market Forecast, 2012-2017

Exhibit ES-6:    Osteobiologics, Market Forecast, 2012-2017

Exhibit ES-7:    2012, Market Shares of Stem Cell Applications for  Bone Healing and Spinal Fusion

Exhibit ES-8:    Orthopedic Biomaterials for Bone Repair and Regeneration, Combined Market Forecast, 2012-2017

 

1. MUSCULOSKELETAL SYSTEM OVERVIEW

1.1 Bone Structure and Function

1.1.1 Cellular Framework

1.1.1.1 Osteoblasts

1.1.1.2 Osteocytes

1.1.1.3 Osteoclasts

1.1.1.4 Osteogenesis

1.1.2 Bone Tissue

1.1.2.1 Cancellous and Cortical Bone Tissue

1.1.2.2 Bone Marrow

1.1.3 Bone Anatomy

1.1.3.1 Diaphysis and Epiphysis

1.1.3.2 Endosteum

1.1.3.3 Periosteum

1.1.4 Joint Components

1.1.4.1 Cartilage

1.1.4.1.1 Elastic Cartilage

1.1.4.1.2 Fibrocartilage

1.1.4.1.3 Hyaline Cartilage

1.1.4.2 Bursae

1.1.4.3 Joint Cavity

1.1.4.4 Menisci

1.1.4.5 Synovial Membrane and Fluid

1.1.4.6 Ligaments and Tendons

1.1.4.7 Muscles

1.1.5 Joint Structures

1.1.5.1 Ankle

1.1.5.2 Digits

1.1.5.3 Elbow

1.1.5.4 Hip

1.1.5.5 Knee

1.1.5.6 Shoulder

1.1.5.7 Wrist

1.1.6 Bone Formation and Remodeling

1.1.6.1 In the Fetus

1.1.6.2 In Childhood

1.1.6.3 In Adulthood

1.1.6.4 In Old Age

1.1.6.5 Mechanical Stress and Wolff’s Law

1.1.7 Factors Affecting Bone Physiology

1.1.7.1 Age

1.1.7.2 Gender

1.1.7.3 Genetic Disposition

1.1.7.4 Hormonal Activity

1.1.7.5 Physical Activity

1.1.7.6 Cigarette Smoking

1.1.7.7 Alcohol and Caffeine Intake

1.1.7.8 Nutritional Deficiencies

1.2 Joint Structure and Function

1.2.1 Types of Joints

1.2.1.1 Synarthroses

1.2.1.2 Amphiarthroses

1.2.1.3 Diarthroses

1.2.1.3.1 Ball-and-Socket

1.2.1.3.2 Condyloid

1.2.1.3.3 Hinge

1.2.1.3.4 Gliding

1.2.1.3.5 Pivot

1.2.2 Arthritis

1.2.2.1 Osteoarthritis

1.2.2.2 Rheumatoid Arthritis

1.3 Management of Joint Disorders

1.3.1 Joint Replacement

1.3.1.1 Dislocation

1.3.1.2 Ligament and Tendon Injuries

1.3.1.3 Meniscal Injuries

 

Exhibit 1-1:      Illustration of Bone Tissue

Exhibit 1-2:      Types of Cartilage

Exhibit 1-3:      Stages of Bone Remodeling

 

2. BIORESORBABLE FIXATION DEVICES

2.1 Materials

2.2 Products

2.2.1 Bioresorbable Pins

2.2.2 Bioresorbable Screws, Nails, and Tacks

2.2.3 Bioresorbable Interference Screws

2.2.4 Bioresorbable Suture Anchors

2.2.5 Bioresorbable Meniscal Repair Devices

2.3 Market Analysis

2.3.1 Potential Market for Bioresorbable Fixation Devices

2.3.1.1 Meniscal Repair

2.3.1.2 Cruciate Ligament Fixation

2.3.1.3 Shoulder Reconstruction

2.3.1.4 Small Joint/Bone Fragment Fixation

2.4 Competitive Analysis

 

Exhibit 2-1:      Advantages of Bioresorbable Fixation Devices

Exhibit 2-2:      Factors Affecting the Properties of Bioresorbable Polymers

Exhibit 2-3:      Types of Bioresorbable Fixation Devices

Exhibit 2-4:      2013, Selected Bioresorbable Pins

Exhibit 2-5:      2013, Selected Bioresorbable Nails, Screws, and Tacks

Exhibit 2-6:      2013, Selected Bioresorbable Interference Screws

Exhibit 2-7:      2013, Selected Bioresorbable Suture Anchors

Exhibit 2-8:      2013, Selected Bioresorbable Meniscal Repair Devices

Exhibit 2-9:      2012, Bioresorbable Fixation Devices Market, By Procedure Type

Exhibit 2-10:    Bioresorbable Fixation Devices,  Market Forecast, 2012-2017

Exhibit 2-11:    2012, Bioresorbable Fixation Devices Market, Share by Supplier

 

3. BONE ALLOGRAFT AND SYNTHETIC BONE GRAFT PRODUCTS

3.1 Bone Graft Materials

3.1.1 Autograft

3.1.2 Allograft

3.1.2.1 Regulations Governing Allograft Providers

3.1.2.1.1 National Organ Transplant Act

3.1.2.1.2 United States Food and Drug Administration Requirements

3.1.2.2 Donor Screening

3.1.2.3 Recovering Tissue

3.1.2.4 Processing Tissue

3.1.2.5 Tissue Banking Industry

3.1.2.6 Base Tissue

3.1.2.7 Demineralized Bone Matrix Products

3.1.2.8 Machined Bone

3.2 Synthetic Bone Grafts

3.2.1 Products

3.3 Bone Graft Applications

3.3.1 Fracture Repair

3.3.2 Revision Total Joint Surgery

3.3.3 Tumors

3.3.4 Spine

3.4 Market Analysis

3.5 Competitive Analysis

3.5.1 Demineralized Bone Matrix

3.5.2 Machined Bone Allografts

3.5.3 Synthetic Bone Graft Substitutes

 

Exhibit 3-1:      Selected Categories of Bone Grafts

Exhibit 3-2:      Base Tissue Bone Allograft Applications in Orthopedic Surgery

Exhibit 3-3:      Base Tissue Bone Allograft Applications in Spine Surgery

Exhibit 3-4:      2013, Description and Representative Pricing of Base Allografts Used in Spine Surgery

Exhibit 3-5:      2013, Selected Demineralized Bone Matrix Products

Exhibit 3-6:      2013, Selected Machined Bone Allografts

Exhibit 3-7:      Materials Used in Bone Graft Substitutes

Exhibit 3-8:      2013, Selected Synthetic Bone Grafts

Exhibit 3-9:      Applications for Bone Grafts

Exhibit 3-10:    Bone Allografts and Synthetic Bone Graft Substitutes, Market Forecast, 2012-2017

Exhibit 3-11:    2012, Bone Allografts and Synthetic Bone Graft Substitutes Market, Share by Tissue Type

Exhibit 3-12:    2012, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 3-13:    2012, Machined Bone Allografts Market, Share by Supplier

Exhibit 3-14:    2012, Synthetic Bone Grafts Market, Share by Supplier

 

4. OSTEOBIOLOGICS

4.1 Bone Growth Factors

4.1.1 Bone Morphogenetic Proteins

4.1.1.1 Products

4.1.1.1.1 Infuse Bone Graft

4.1.1.1.2 Osteogenic Protein-1

4.1.1.2 Emerging Products

4.1.1.3 Clinical Trials

4.1.2 Fibroblast Growth Factors

4.1.3 Recombinant Platelet-Derived Growth Factor

4.1.3.1 Products

4.1.4 Autologous (Blood-Derived) Growth Factors

4.1.4.1 Products

4.2 Small Molecules

4.3 Stem Cell Therapy

4.3.1 Products

4.3.2 Emerging Products

4.4 Gene Therapy

4.4.1 Gene Therapy versus Growth Factors

4.4.2 Systemic Gene Therapy

4.4.3 Regional Gene Therapy

4.5 Other Osteobiologics

4.6 Market Analysis

4.6.1 Bone Morphogenetic Proteins

4.6.2 Other Osteobiologics

4.7 Competitive Analysis

 

Exhibit 4-1:      Selected Bone Morphogenetic Proteins

Exhibit 4-2:      Selected Recombinant Human Bone Morphogenetic Protein Products

Exhibit 4-3:      Selected Recombinant Human Bone Morphogenetic Proteins Under Development

Exhibit 4-4:      2013, Selected Autologous Therapy/Platelet Concentrate Systems

Exhibit 4-5:      2013, Selected Growth Factor and Small Molecule Therapies Under Development for Bone Healing and Spinal Fusion Applications

Exhibit 4-6:      2013, Selected Stem Cell Products for Bone Healing and Enhancement of Spinal Fusion

Exhibit 4-7:      2013, Selected Stem Cell Products Under Development for Orthopedic and Spinal Fusion Applications

Exhibit 4-8:      Comparison of Growth Factors with Gene Therapy for Bone Repair

Exhibit 4-9:      Gene Therapy Delivery Methods for Bone Repair

Exhibit 4-10:    Recombinant Human Bone Morphogenetic Protein Products, Market Forecast, 2012-2017

Exhibit 4-11:    Stem Cells and Other Osteobiologic Agents for Bone Healing and Enhancement of Spinal Fusion, Market Forecast, 2012-2017

Exhibit 4-12:    2012, Market Shares of Stem Cell Applications for Bone Healing and Spinal Fusion

Exhibit 4-13:    2012, Stem Cell Products Market for Bone Healing and Spinal Fusion, Share by Supplier

 

5. COMPANY PROFILES

5.1       Arthrex, Inc.

5.2       Baxter International, Inc.

5.3       Johnson & Johnson

5.4       LifeNet Health, Inc.

5.5       Medtronic, Inc.

5.6       Musculoskeletal Transplant Foundation, Inc.

5.7       NuVasive, Inc.

5.8       Orthofix International NV

5.9       RTI Biologics, Inc.

5.10     Smith & Nephew PLC

5.11     Stryker Corporation

 

APPENDIX:  COMPANY LISTING

 

To order reports or obtain information about special pre-publication offers from within the U.S., contact custcare@informa.com. You can also call 1.908.748.1221 (or toll-free within the U.S. at 1.800.332.2181) or fax 1.908.748.1222.

 

The Newsletter | The Principals | Reports | Conferences | Physician Surveys | Consulting | Contact Us | Home