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U.S. Markets for Arthroscopic and Osteoconductive and Osteoinductive Products
Report #A327 - August 2011
180 Pages – 51 Exhibits – 9 Company Profiles

The aging of the population and longer and more active lifestyles are some of the factors that are driving the United States (U.S.) market for arthroscopic and osteoconductive and osteoinductive products. This market, as covered by the scope of this report, includes arthroscopy devices; bone growth stimulation products; and allografts, bone morphogenetic proteins (BMPs), and synthetic bone substitutes.

During the forecast period covered by this report, the value of the U.S. market for allograft, BMP, and synthetic bone substitute products is projected to grow at a compound annual rate of 4.9%, from approximately $1,857.4 million in 2010 to an estimated $2,364.0 million in the year 2015. During the same period, the U.S. market for bone growth stimulation products for fracture healing and spinal fusion is projected to increase at a compound annual rate of 6.4%, from approximately $569 million in 2010 to an estimated $775 million in the year 2015, while the U.S. market for arthroscopy products is projected to grow at a compound annual rate of 5.6%, from approximately $1,416.9 million in 2010 to an estimated $1,859.1 million in the year 2015.

This new report from Medtech Insight is the third in a series of reports analyzing the U.S. orthopedic products market; previously published reports in this series include Report #A326, "U.S. Markets for Fracture Fixation Products," and Report #A313, "U.S. Markets for Joint Replacement and Reconstruction Products."

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U.S. Markets for Arthroscopic and Osteoconductive and Osteoinductive Products

A327

August 2011

$3,750
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Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

 

EXECUTIVE SUMMARY

i.      Clinical Overview

a.     Osteoconductive Materials

b.     Osteoinductive Materials

ii.     Allografts, Autografts, Bone Morphogenetic Proteins, and Synthetic Bone Substitutes

a.     Autografts

b.     Allografts

c.     Synthetic Bone Substitutes

d.     Bone Morphogenetic Proteins

e.     Market Forecast

iii.    Bone Growth Stimulation Products

a.     Market Forecast

iv.    Arthroscopy Products

a.     Procedure Volumes

b.     Market Forecast

v.     Methodology

 

Exhibit ES-1:    Allograft, Bone Morphogenetic Protein, and Synthetic Bone Substitute Products, Combined Market Forecast, 2010-2015

Exhibit ES-2:    Bone Growth Stimulation Products for Fracture Repair and Spinal Fusion, Market Forecast, 2010-2015

Exhibit ES-3:    Knee and Shoulder Arthroscopy, Procedure Volumes Forecast, 2010-2015

Exhibit ES-4:    Arthroscopy Products, Combined Market Forecast, 2010-2015

 

1. CLINICAL OVERVIEW OF BONES AND JOINTS

1.1 Bone Structure and Function

1.1.1 Cellular Framework

1.1.1.1 Osteoblasts/Osteocytes

1.1.1.2 Osteoclasts

1.1.1.3 Osteogenesis

1.1.2 Collagen

1.1.3 Bone Marrow

1.2 Ligaments and Tendons

1.3 Joint Structure and Function

1.3.1 Knee

1.3.2 Hip

1.3.3 Extremities/Small Bones

1.3.3.1 Shoulder

1.3.3.2 Elbow

1.3.3.3 Hand and Wrist

1.3.3.4 Foot and Ankle

1.3.4 Vertebrae

 

Exhibit 1-1:      Common Bone Anatomy Terms

Exhibit 1-2:      Structure of Bone

Exhibit 1-3:      Structure of Hydroxyapatite

Exhibit 1-4:      Structure of Collagen

Exhibit 1-5:      Anatomy of the Knee

Exhibit 1-6:      Anatomy of the Hip

Exhibit 1-7:      Anatomy of the Shoulder:  The Rotator Cuff

Exhibit 1-8:      Anatomy of the Shoulder:  The Glenoid Cavity

Exhibit 1-9:      Anatomy of the Elbow

Exhibit 1-10:    Anatomy of the Hand

Exhibit 1-11:    Anatomy of the Spine

 

2. FRACTURE EPIDEMIOLOGY AND ETIOLOGY

2.1 Fracture Etiology

2.2 Bone Fracture Classification

2.3 Long Bone Fracture Fixation

2.3.1 Humerus

2.3.2 Radius and Ulna

2.3.3 Femur

2.3.4 Tibia/Fibula

2.3.5 Clavicle

2.4 Fractures of the Ankle, Hand, Foot, and Wrist

2.5 Fracture Break Patterns

2.6 Growth Plate Fractures

2.7 Fracture Healing Mechanisms

 

Exhibit 2-1:      2007, Incidence of Bone Fractures, by Anatomic Site

Exhibit 2-2:      2006, Physician Visits for Bone Fractures, By Anatomic Site

Exhibit 2-3:      Classification of Bone Fractures

Exhibit 2-4:      Long Bone Fractures

Exhibit 2-5:      The Fracture Healing Process

 

3. ALLOGRAFT, BONE MORPHOGENETIC PROTEIN, AND SYNTHETIC BONE SUBSTITUTE PRODUCTS MARKET

3.1 Osteoconductive and Osteoinductive Materials

3.1.1 Autografts

3.1.2 Allografts

3.1.2.1 Regulations Governing Allograft Providers

3.1.2.1.1 National Organ Transplant Act

3.1.2.1.2 United States Food and Drug Administration Requirements

3.1.2.2 Donor Screening

3.1.2.3 Recovering Tissue

3.1.2.4 Processing Tissue

3.1.2.5 Allograft Materials

3.1.2.5.1 Support Structures

3.1.2.5.2 Osteoconductive Fillers

3.1.2.5.3 Osteoinductive Materials

3.1.2.6 Allograft Applications

3.1.2.6.1 Fracture Repair

3.1.2.6.2 Revision Total Joint Surgery

3.1.2.6.3 Tumors

3.1.2.6.4 Spinal Fusion

3.1.2.7 Allograft Tissue Providers

3.1.2.8 Market Analysis

3.1.2.8.1 Arthroplasty Market

3.1.2.8.2 Fracture Repair Market

3.1.2.8.3 Spine Market

3.1.2.8.4 Other (Primarily Hand and Foot Bone Grafting) Market

3.1.2.8.5 Combined Market

3.1.2.9 Competitive Analysis

3.1.3 Synthetic Bone Substitutes

3.1.3.1 Products

3.1.3.2 Market Analysis

3.1.3.3 Competitive Analysis

3.1.4 Bone Morphogenetic Proteins

3.1.4.1 Products

3.1.4.1.1 Infuse Bone Graft

3.1.4.1.2 Osteogenic Protein-1

3.1.4.1.3 Emerging Products

3.1.4.2 Market Analysis

3.1.4.3 Competitive Analysis

3.1.5 Combined Market Forecast

 

Exhibit 3-1:      Comparison of Selected Suppliers of Allograft Bone Tissue and Their Tissue Constructs

Exhibit 3-2:      Allografts Used in Arthroplasty, Market Forecast, 2010-2015

Exhibit 3-3:      Allografts Used in Fracture Repair, Market Forecast, 2010-2015

Exhibit 3-4:      Allografts Used in Spine Surgery, Market Forecast, 2010-2015

Exhibit 3-5:      Allografts Used in Other Orthopedic Procedures, Market Forecast, 2010-2015

Exhibit 3-6:      Orthopedic Allografts, Combined Market Forecast, 2010-2015

Exhibit 3-7:      2010, Orthopedic Allografts Market, Share by Supplier

Exhibit 3-8:      2011, Selected Synthetic Bone Substitute Products

Exhibit 3-9:      Synthetic Bone Substitute Products, Market Forecast, 2010-2015

Exhibit 3-10:    2010, Synthetic Bone Substitute Products Market, Share by Supplier

Exhibit 3-11:    2011, Selected Bone Morphogenetic Protein Products

Exhibit 3-12:    2011, Selected Bone Morphogenetic Protein Products Under Development

Exhibit 3-13:    Bone Morphogenetic Protein Products, Market Forecast, 2010-2015

Exhibit 3-14:    Allograft, Bone Morphogenetic Protein, and Synthetic Bone Substitute Products, Combined Market Forecast, 2010-2015

 

4. BONE GROWTH STUMULATION PRODUCTS MARKET

4.1 Capacitive Coupling Bone Growth Stimulators

4.2 Combined Magnetic Field Stimulators

4.3 Direct Current Stimulators

4.4 Pulsed Electromagnetic Field Bone Growth Stimulators

4.5 Ultrasound Bone Growth Stimulators

4.6 Reimbursement

4.7 Products

4.7.1 Fracture Healing Bone Growth Stimulators

4.7.2 Spinal Fusion Bone Growth Stimulators

4.8 Market Analysis

4.8.1 Fracture Healing Bone Growth Stimulators

4.8.2 Spinal Fusion Bone Growth Stimulators

4.8.3 Combined Market Forecast

4.9 Competitive Analysis

4.9.1 Fracture Repair Market

4.9.2 Spinal Fusion Market

4.9.3 Combined Market

 

Exhibit 4-1:      Indications for Bone Growth Stimulation Products for Fracture Repair

Exhibit 4-2:      Indications for Bone Growth Stimulation Products for Spinal Fusion

Exhibit 4-3:      2011, Selected Bone Growth Stimulation Products Used in Fracture Repair

Exhibit 4-4:      2011, Selected Bone Growth Stimulation Products Used in Spinal Fusion

Exhibit 4-5:      Bone Growth Stimulation Products for Fracture Repair and Spinal Fusion, Market Forecast, 2010-2015

Exhibit 4-6:      2010, Market for Bone Growth Stimulation Products for Fracture Repair, Share by Supplier

Exhibit 4-7:      2010, Market for Bone Growth Stimulation Products for Spinal Fusion, Share by Supplier

Exhibit 4-8:      2010, Combined Market for Bone Growth Stimulation Products for Fracture Repair and Spinal Fusion, Share by Supplier

 

5. ANTHROSCOPY PRODUCTS MARKET

5.1 Arthroscopic Treatment Overview

5.1.1 Background

5.1.2 Newer Applications

5.2 Arthroscopy for Sports Injuries

5.3 Products

5.4 Procedure Volumes

5.4.1 Knee Arthroscopy

5.4.2 Shoulder Arthroscopy

5.5 Arthroscopy Market Analysis

5.5.1 Knee Arthroscopy

5.5.2 Shoulder Arthroscopy

5.5.3 Other Arthroscopic Procedures

5.5.4 Combined Market Forecast

5.5.5 Competitive Analysis

 

Exhibit 5-1:      Common Knee Injuries

Exhibit 5-2:      Arthroscopic Access Ports for the Knee

Exhibit 5-3:      2011, Selected Arthroscopy Products

Exhibit 5-4:      Knee and Shoulder Arthroscopy, Procedure Volumes Forecast, 2010-2015

Exhibit 5-5:      Knee Arthroscopy Products, Market Forecast, 2010-2015

Exhibit 5-6:      Shoulder Arthroscopy Products, Market Forecast, 2010-2015

Exhibit 5-7:      Other Arthroscopy Products, Market Forecast, 2010-2015

Exhibit 5-8:      Arthroscopy Products, Combined Market Forecast, 2010-2015

Exhibit 5-9:      2010, Combined Market, Arthroscopy Products, Share by Supplier

 

6. COMPANY PROFILES

6.1 ApaTech, Inc./Baxter International, Inc.

6.2 Arthrex, Inc.

6.3 Biomet, Inc.

6.4 Medtronic, Inc.

6.5 Orthofix Holdings, Inc.

6.6 Orthovita, Inc./Stryker Corporation

6.7 RTI Biologics, Inc.

6.8 Smith & Nephew PLC

6.9 Wright Medical Group, Inc.

 

APPENDIX: COMPANY LISTING

 

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