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European Markets for Bone Graft Substitute Products for Spinal Fusion
Report #A329 - November 2011
112 Pages – 51 Exhibits – 10 Company Profiles

The European market for bone graft substitute products for spinal fusion is projected to experience significant growth over the next half-decade due to a number of factors, particularly an increased prevalence of degenerative disc disease. This new report from Medtech Insight/Elsevier Business Intelligence provides market forecasts and analysis of the European market for bone graft substitute products including bone morphogenetic proteins, demineralized bone matrix, and synthetic bone graft substitutes.

In 2010, the value of the European market for bone graft substitute products for spinal fusion totaled approximately $177.1 million; during the forecast period covered by this report, this market is projected to grow at a compound annual rate of 17.3%, reaching an estimated $461.7 million in the year 2016.

This newly published report from Medtech Insight includes a clinical overview of the various bone graft substitutes in use in Europe, a review of the leading drivers and limiters of the European bone graft substitutes products market, and an analysis of the leading competitors and their individual market shares. This is the second in a two-part series of reports on the European market for spinal fusion products.

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 Report# Publication
Date		 List Price

European Markets for Bone Graft Substitute Products for Spinal Fusion

A329

November 2011

$4,850
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Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

 

EXECUTIVE SUMMARY

i.       Clinical Overview

ii.       Demineralized Bone Matrix

a.     Market Forecast

iii.      Synthetic Bone Graft Substitutes

a.     Market Forecast

iv.      Bone Morphogenetic Proteins

a.     Market Forecast

v.      Combined Market Analysis

vi.      Methodology

 

Exhibit ES-1:    Europe, Bone Graft Substitute Products for Spinal Fusion, Combined Market Forecast, 2010-2016

 

1. ANATOMY AND PHYSIOLOGY OF THE SPINE

1.1 Spinal Anatomy

1.1.1 Vertebrae

1.1.2 Spinal Canal

1.2 Selected Spinal Disorders

1.2.1 Disc Herniation

1.2.2 Degenerative Disc Disease

1.2.2.1 Arthritis

1.2.2.1.1 Osteoarthritis

1.2.2.1.2 Rheumatoid Arthritis

1.2.2.1.3 Ankylosing Spondylitis

1.2.2.2 Osteoporosis

1.2.2.3 Spondylosis

1.2.3 Abnormal Curvature of the Spine

1.2.3.1 Scoliosis

1.2.3.2 Kyphosis and Lordosis

1.2.4 Spondylolisthesis

1.2.5 Stenosis

1.2.6 Spinal Tumors

1.2.7 Traumatic Spinal Injuries

1.2.8 Vertebral Fractures

 

Exhibit 1-1:      Lateral View of the Spinal Column

Exhibit 1-2:      Axial and Lateral Views of the Thoracic Vertebrae

Exhibit 1-3:      Axial and Lateral Views of the Lumbar Vertebrae

Exhibit 1-4:      Stages of Disc Herniation

Exhibit 1-5:      Common Degenerative Spinal Disorders

Exhibit 1-6:      Lumbar and Thoracic Scoliosis

Exhibit 1-7:      A Kyphotic versus a Normal Spine

Exhibit 1-8:      A Lordotic versus a Normal Spine

Exhibit 1-9:      A Healthy Cervical Spine Compared with Spinal Stenosis and Disc Herniation

 

2. THE EUROPEAN MARKET FOR DEMINERALIZED BONE MATRIX AND SYNTHETIC BONE GRAFT SUBSTITUTES

2.1 Bone Graft Characteristics

2.2 Demineralized Bone Matrix

2.2.1 Selected Demineralized Bone Matrix Products

2.2.1.1 DePuy/Johnson & Johnson

2.2.1.2 Integra LifeSciences

2.2.1.3 Medtronic

2.2.1.4 Scient’x/Alphatec Spine

2.2.1.5 Smith & Nephew

2.2.1.6 Wright Medical Technology/Wright Medical Group

2.2.1.7 Zimmer

2.3 Synthetic Bone Graft Substitutes

2.3.1 Selected Synthetic Bone Graft Substitute Products

2.3.1.1 Biomet

2.3.1.2 DePuy/Johnson & Johnson

2.3.1.3 Graftys

2.3.1.4 Integra LifeSciences

2.3.1.5 LDR Médical/LDR Holding

2.3.1.6 Medtronic

2.3.1.7 Smith & Nephew

2.3.1.8 Synthes

2.3.1.9 Wright Medical Technology/Wright Medical Group

2.3.1.10 Zimmer

2.4 Market Analysis

2.5 Competitive Analysis

 

Exhibit 2-1:      2011, Selected Demineralized Bone Matrix Products

Exhibit 2-2:      2011, Selected Synthetic Bone Graft Substitute Products

Exhibit 2-3:      Europe, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-4:      France, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-5:      Germany, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-6:      Italy, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-7:      Spain, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-8:      United Kingdom, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-9:      Benelux, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-10:    Nordic Countries, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-11:    Rest of Europe, Bone Graft Substitutes, Market Forecast, 2010-2016

Exhibit 2-12:    2010, Europe, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-13:    2010, France, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-14:    2010, Germany, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-15:    2010, Italy, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-16:    2010, Spain, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-17:    2010, United Kingdom, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-18:    2010, Benelux, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-19:    2010, Nordic Countries, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-20:    2010, Rest of Europe, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 2-21:    2010, Europe, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-22:    2010, France, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-23:    2010, Germany, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-24:    2010, Italy, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-25:    2010, Spain, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-26:    2010, United Kingdom, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-27:    2010, Benelux, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-28:    2010, Nordic Countries, Synthetic Bone Graft Substitutes Market, Share by Supplier

Exhibit 2-29:    2010, Rest of Europe, Synthetic Bone Graft Substitutes Market, Share by Supplier

 

3. THE EUROPEAN MARKET FOR  RECOMBINANT BONE MORPHOGENETIC PROTEIN PRODUCTS FOR SPINAL FUSION

3.1 Clinical Overview

3.2 Products

3.2.1 InductOs

3.2.2 Opgenra

3.3 Market Analysis

3.4 Competitive Analysis

 

Exhibit 3-1:      Selected Bone Morphogenetic Proteins

Exhibit 3-2:      2011, Selected Recombinant Bone Morphogenetic Protein Products for Spinal Fusion

Exhibit 3-3:      Europe, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-4:      France, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-5:      Germany, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-6:      Italy, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-7:      Spain, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-8:      United Kingdom, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-9:      Benelux, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-10:    Nordic Countries, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-11:    Rest of Europe, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016

Exhibit 3-12:    2010, Europe, Bone Morphogenetic Protein Products Market, By Country

 

4. COMPANY PROFILES

4.1       DePuy Spine, Inc./Johnson & Johnson

4.2       Graftys SA

4.3       Integra LifeSciences Corporation

4.4       LDR Médical/LDR Holding

4.5       Medtronic, Inc.

4.6       Scient’x SA/Alphatec Holdings, Inc.

4.7       Smith & Nephew PLC

4.8       Synthes, Inc.

4.9       Wright Medical Technology, Inc./Wright Medical Group

4.10     Zimmer Holdings, Inc.

 

APPENDIX:  COMPANY LISTING

 

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