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U.S. Markets for Drug and Fluid Delivery Devices
Report #A354 - June 2012
277 Pages – 73 Exhibits – 23 Company Profiles

Pharmacotherapy represents the first-line treatment in the management of most chronic and transient medical conditions warranting therapeutic intervention in the U.S. To date, more than 40,000 prescription drug products containing 2,700 active ingredients have been approved by the FDA; these products accounted for more than 70% of the national pharmaceutical usage in 2011. In the same year, U.S. pharmacies processed approximately 3.6 billion prescriptions, generating an estimated $300.0 billion in cumulative pharmaceutical sales and representing nearly 12.5% of the nation’s total healthcare spending. This report covers injection/infusion, transdermal, and inhalation drug delivery devices. In 2011, U.S. sales of these devices totalled nearly $22 billion; over the forecast period covered by this report, sales are expected to increase at a compound annual rate of 5.4%, reaching more than $28 billion in the year 2016.

This new report by Medtech Insight presents a detailed overview of the U.S. drug and fluid delivery devices market. Major topics covered by this report include an overview of drug delivery technologies, injection/infusion drug delivery systems (e.g., syringes, injection pens, needleless jet injectors, infusion pumps and disposables, gravity infusion systems, and vascular access devices), transdermal drug delivery systems (e.g., patch-based pharmaceutical products for cardiovascular disease management, central nervous system disorder management, hormone replacement therapy, acute and chronic pain management, and urologic disorder management), and inhalation drug delivery systems (e.g., inhaled insulin delivery systems and inhaled respiratory drug systems such as dry powder inhaler- and metered dose inhaler-based preparations for the treatment of asthma, chronic obstructive pulmonary disease, and cystic fibrosis).

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U.S. Markets for Drug and Fluid Delivery Devices

A354

June 2012

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Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

 

EXECUTIVE SUMMARY

i.       Injection/Infusion Drug Delivery Systems

ii.       Transdermal Drug Delivery Systems

iii.      Inhalation Drug Delivery Systems

iv.      Combined Market Forecast

 

Exhibit ES-1:    Injection/Infusion Drug Delivery Systems, Market Forecast, 2011-2016

Exhibit ES-2:    Patch-Based Transdermal Pharmaceutical Products, Market Forecast, 2011-2016

Exhibit ES-3:    Inhalation Drug Delivery Products, Market Forecast, 2011-2016

Exhibit ES-4:    Drug and Fluid Delivery Devices, Combined Market Forecast, 2011-2016

 

1. OVERVIEW OF DRUG DELIVERY

1.1 Oral Drug Delivery

1.1.1 Access Pharmaceuticals

1.1.2 Emisphere Technologies

1.1.3 Lipocine

1.2 Transdermal Drug Delivery

1.3 Transmucosal Drug Delivery

1.3.1 Generex Biotechnology

1.4 Inhalation Drug Delivery

1.5 Injection/Infusion Drug Delivery

1.5.1 Injection

1.5.2 Infusion

1.5.2.1 Intraoperative Site Infusion

1.5.2.2 Intraperitoneal/Transperitoneal Infusion

1.5.2.3 Intraspinal Infusion

1.5.2.4 Intravascular Infusion

 

Exhibit 1-1:      Advantages and Disadvantages of Selected Drug Delivery Methods

 

2. INJECTION/INFUSION DRUG DELIVERY SYSTEMS

2.1 Clinical Applications

2.1.1 Anesthesia Therapy

2.1.2 Antibiotic/Antiviral Therapy

2.1.3 Bone Marrow Transplant Therapy

2.1.4 Organ Transplant Therapy

2.1.5 Cardiovascular Disease Infusion Therapy

2.1.5.1 Anticoagulant and Thrombolytic Therapy

2.1.5.2 Heart Failure Management

2.1.6 Chemotherapy

2.1.7 Diabetes Management

2.1.8 Hydration Therapy

2.1.9 Nutritional Support

2.1.9.1 Total Parenteral Nutrition

2.1.9.2 Enteral Nutrition

2.1.10 Pain Management

2.1.11 Transfusion Therapy

2.1.12 Other Infusion-Based Drug Therapies

2.1.12.1 Cytokine Therapy

2.1.12.2 Growth Hormone Therapy

2.1.12.3 Interferon Therapy

2.1.12.4 Infertility Therapy

2.1.12.5 High-Risk Pregnancy Management

2.1.12.6 Perinatal Therapy

2.2 Products and Technologies

2.2.1 Syringe Products

2.2.1.1 Multipurpose Standard Syringes

2.2.1.2 Multipurpose Safety Syringes

2.2.1.3 Insulin Syringes

2.2.1.4 Market Analysis

2.2.1.5 Competitive Analysis

2.2.2 Injection Pen Products

2.2.2.1 Market Analysis

2.2.2.2 Competitive Analysis

2.2.3 Needleless Jet Injector Products

2.2.3.1 Market Analysis

2.2.3.2 Competitive Analysis

2.2.4 Infusion Pump Products

2.2.4.1 Volumetric Pumps

2.2.4.1.1 Market Analysis

2.2.4.1.2 Competitive Analysis

2.2.4.2 Syringe Pumps

2.2.4.2.1 Market Analysis

2.2.4.2.2 Competitive Analysis

2.2.4.3 Ambulatory Pumps

2.2.4.3.1 Market Analysis

2.2.4.3.2 Competitive Analysis

2.2.4.4 Disposable Pumps

2.2.4.4.1 Market Analysis

2.2.4.4.2 Competitive Analysis

2.2.4.5 Implantable Pumps

2.2.4.5.1 Market Analysis

2.2.4.5.2 Competitive Analysis

2.2.4.6 Insulin Pumps

2.2.4.6.1 Market Analysis

2.2.4.6.2 Competitive Analysis

2.2.4.7 Enteral Pumps and Gravity Systems

2.2.4.7.1 Market Analysis

2.2.4.7.2 Competitive Analysis

2.2.4.8 Intravascular Gravity Infusion Systems

2.2.4.8.1 Market Analysis

2.2.4.8.2 Competitive Analysis

2.2.5 Vascular Access Products

2.2.5.1 Short Peripheral Catheters

2.2.5.1.1 Market Analysis

2.2.5.1.2 Competitive Analysis

2.2.5.2 Midline Catheters

2.2.5.2.1 Market Analysis

2.2.5.2.2 Competitive Analysis

2.2.5.3 Peripherally Inserted Central Catheters

2.2.5.3.1 Market Analysis

2.2.5.3.2 Competitive Analysis

2.2.5.4 Central Venous Catheters

2.2.5.4.1 Market Analysis

2.2.5.4.2 Competitive Analysis

2.2.5.5 Implantable Ports

2.2.5.5.1 Market Analysis

2.2.5.5.2 Competitive Analysis

 

Exhibit 2-1:      Injection/Infusion Drug Delivery Systems, Combined Market Forecast, 2011-2016

Exhibit 2-2:      2012, Selected Safety Syringes

Exhibit 2-3:      2012, Selected Insulin Syringes

Exhibit 2-4:      Multipurpose and Insulin Syringes, Market Forecast 2011-2016

Exhibit 2-5:      2011, Multipurpose and Insulin Syringes Market, Share by Supplier

Exhibit 2-6:      2012, Selected Insulin Pens

Exhibit 2-7:      Insulin Pen Products, Market Forecast, 2011-2016

Exhibit 2-8:      2011, Insulin Pen Products Market, Share by Supplier

Exhibit 2-9:      2012, Selected Needleless Jet Injectors

Exhibit 2-10:    Needleless Jet Injectors, Market Forecast, 2011-2016

Exhibit 2-11:    2011, Needleless Jet Injectors Market, Share by Supplier

Exhibit 2-12:    Infusion Pumps, Combined Market Forecast, 2011-2016

Exhibit 2-13:    2012, Selected Volumetric Pumps

Exhibit 2-14:    Volumetric Pumps and Disposables, Market Forecast, 2011-2016

Exhibit 2-15:    2011, Volumetric Pumps and Disposables Market, Share by Supplier

Exhibit 2-16:    2012, Selected Syringe Pumps

Exhibit 2-17:    Syringe Pumps and Disposables, Market Forecast, 2011-2016

Exhibit 2-18:    2011, Syringe Pumps and Disposables Market, Share by Supplier

Exhibit 2-19:    2012, Selected Ambulatory Pumps

Exhibit 2-20:    Ambulatory Pumps, Market Forecast, 2011-2016

Exhibit 2-21:    2011, Ambulatory Pumps and Disposables Market, Share by Supplier

Exhibit 2-22:    2012, Selected Disposable Infusion Pumps

Exhibit 2-23:    Disposable Infusion Pumps, Market Forecast, 2011-2016

Exhibit 2-24:    2011, Disposable Infusion Pumps Market, Share by Supplier

Exhibit 2-25:    Implantable Infusion Pumps, Market Forecast, 2011-2016

Exhibit 2-26:    2011, Implantable Infusion Pumps Market, Share by Supplier

Exhibit 2-27:    2012, Selected Insulin Pumps

Exhibit 2-28:    Insulin Pumps and Disposables, Market Forecast, 2011-2016

Exhibit 2-29:    2011, Insulin Pumps and Disposables Market, Share by Supplier

Exhibit 2-30:    2012, Selected Enteral Nutrition Pumps

Exhibit 2-31:    Enteral Pumps, Disposables, and Gravity Sets, Market Forecast, 2011-2016

Exhibit 2-32:    2011, Enteral Pumps, Disposables, and Gravity Sets Market, Share by Supplier

Exhibit 2-33:    Intravenous Gravity Infusion Systems, Market Forecast, 2011-2016

Exhibit 2-34:    2011, Intravenous Gravity Infusion Systems Market, Share by Supplier

Exhibit 2-35:    2012, Selected Vascular Access Devices

Exhibit 2-36:    Vascular Access Devices, Combined Market Forecast, 2011-2016

Exhibit 2-37:    Short Peripheral Catheters, Market Forecast, 2011-2016

Exhibit 2-38:    2011, Short Peripheral Catheters Market, Share by Supplier

Exhibit 2-39:    Midline Catheters, Market Forecast, 2011-2016

Exhibit 2-40:    2011, Midline Catheters Market, Share by Supplier

Exhibit 2-41:    Peripherally Inserted Central Catheters, Market Forecast, 2011-2016

Exhibit 2-42:    2011, Peripherally Inserted Central Catheters Market, Share by Supplier

Exhibit 2-43:    Central Venous Catheters, Market Forecast, 2011-2016

Exhibit 2-44:    2011, Central Venous Catheters Market, Share by Supplier

Exhibit 2-45:    Implantable Ports, Market Forecast, 2011-2016

Exhibit 2-46:    2011, Implantable Ports Market, Share by Supplier

 

3. TRANSDERMAL DRUG DELIVERY SYSTEMS

3.1 Technology

3.1.1 Passive Transdermal Transport Systems

3.1.1.1 3M Health Care/3M

3.1.1.2 NanoPass Technologies

3.1.1.3 Zosano Pharma

3.1.2 Active Transdermal Transport Systems

3.1.2.1 Echo Therapeutics

3.1.2.2 Inovio Pharmaceuticals

3.1.2.3 IOMED/DJO

3.1.2.4 Teikoku Pharma

3.1.2.5 Vyteris

3.2 Clinical Applications

3.2.1 Cardiovascular Disease Management

3.2.1.1 Products

3.2.1.2 Market Analysis

3.2.1.3 Competitive Analysis

3.2.2 Central Nervous System Disorder Management

3.2.2.1 Products

3.2.2.2 Market Analysis

3.2.2.3 Competitive Analysis

3.2.3 Hormone Replacement Therapy

3.2.3.1 Products

3.2.3.2 Market Forecast

3.2.3.3 Competitive Analysis

3.2.4 Pain Management

3.2.4.1 Cancer-Related Pain

3.2.4.2 Post-Herpetic Neuralgia

3.2.4.3 Products

3.2.4.4 Market Analysis

3.2.4.5 Competitive Analysis

3.2.5 Urologic Disorder Management

3.2.5.1 Products

3.2.5.2 Market Analysis

 

Exhibit 3-1:      2012, Selected Microneedle Array Systems

Exhibit 3-2:      2012, Selected Directed Energy-Assisted Transdermal Macromolecular Transport Products

Exhibit 3-3:      Patch-Based Pharmaceutical Products, by Application, Combined Market Forecast, 2011-2016

Exhibit 3-4:      2012, Selected Patch-Based Clonidine and Nitroglycerin Products

Exhibit 3-5:      Patch-Based Clonidine and Nitroglycerin Products, Market Forecast, 2011-2016

Exhibit 3-6:      2011, Patch-Based Clonidine and Nitroglycerin Products Market, Share by Supplier

Exhibit 3-7:      2012, Selected Patch-Based Central Nervous System Treatment Products

Exhibit 3-8:      Patch-Based Central Nervous System Disorder Treatment Products, Market Forecast, 2011-2016

Exhibit 3-9:      2011, Patch-Based Central Nervous System Disorder Treatment Products Market, Share by Supplier

Exhibit 3-10:    2012, Selected Patch-Based Estrogen Replacement Products

Exhibit 3-11:    Patch-Based Estrogen Replacement Products, Market Forecast, 2011-2016

Exhibit 3-12:    2011, Patch-Based Estrogen Replacement Products Market, Share by Supplier

Exhibit 3-13:    2012, Selected Patch-Based Pain Management Products

Exhibit 3-14:    Patch-Based Pain Management Products, Market Forecast, 2011-2016

Exhibit 3-15:    2011, Patch-Based Pain Management Products Market, Share by Supplier

Exhibit 3-16:    2012, Selected Patch-Based Urologic Treatment Products

Exhibit 3-17:    Patch-Based Urologic Treatment Products, Market Forecast, 2011-2016

 

4. INHALATION DRUG DELIVERY SYSTEMS

4.1 Chronic Respiratory Disorder Management

4.1.1 Bronchial Asthma

4.1.2 Chronic Bronchitis

4.1.3 Pulmonary Emphysema

4.1.4 Cystic Fibrosis

4.1.5 Obstructive Pulmonary Disorder Management

4.1.5.1 Allergy-Blocking Agents

4.1.5.2 Anti-Inflammatory Agents

4.1.5.3 Bronchodilators

4.2 Diabetes Management

4.3 Emerging Applications

4.3.1 Alkermes

4.3.2 Aradigm

4.3.3 MannKind

4.3.4 Nektar Therapeutics

4.4 Technology

4.4.1 Metered Dose Inhalers

4.4.1.1 Breath-Actuated Metered Dose Inhalers

4.4.1.2 Chlorofluorocarbon-Free Metered Dose Inhalers

4.4.1.3 Spacers for Use with Metered Dose Inhalers

4.4.2 Dry Powder Inhalers

4.4.3 Nebulizers

4.5 Products

4.6 Market Analysis

4.7 Competitive Analysis

 

Exhibit 4-1:      2012, Selected Inhalation Therapy Agents

Exhibit 4-2:      Advantages and Disadvantages of Inhalation Drug Delivery Devices

Exhibit 4-3:      2012, Selected Dry Powder Inhalers and Metered Dose Inhalers

Exhibit 4-4:      Inhalation Drug Delivery Products, Market Forecast, 2011-2016

Exhibit 4-5:      2011, Inhalation Respiratory Drug Delivery Products Market, Share by Supplier

 

5. COMPANY PROFILES

5.1       Abbott Laboratories

5.2       C.R. Bard, Inc.

5.3       Baxter Healthcare Corporation/Baxter International, Inc.

5.4       Bayer AG

5.5       BD (Becton, Dickinson and Company)

5.6       Bioject Medical Technologies, Inc.

5.7       Boehringer Ingelheim GmbH

5.8       B. Braun Melsungen AG

5.9       CareFusion Corporation

5.10     Endo Pharmaceuticals Holdings, Inc.

5.11     GlaxoSmithKline PLC

5.12     Hospira, Inc.

5.13     I-Flow Corporation/Kimberly-Clark Corporation

5.14     Johnson & Johnson

5.15     Kendall Healthcare/Covidien LTD

5.16     Medtronic, Inc.

5.17     Merck & Co., Inc.

5.18     Mylan Laboratories, Inc.

5.19     Novartis AG

5.20     Noven Pharmaceuticals, Inc./Hisamitsu Pharmaceutical Co., Inc.

5.21     Novo Nordisk AS

5.22     Smiths Medical, Inc./Smiths Group PLC

5.23     Teleflex Medical, Inc./Teleflex, Inc.

 

APPENDIX: COMPANY LISTING

 

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