EXECUTIVE
SUMMARY
i. New Cancer Cases, Cancer
Prevalence, and Deaths Due to Cancer
ii. Diagnostic Oncology Procedures
iii. Diagnostic Oncology Products
a. Diagnostic Imaging Platforms
i. Conventional X-Ray-Based Imaging
Systems
ii. Mammography Systems
iii. Computed Tomography Systems
iv. Magnetic Resonance Imaging Systems
v. Nuclear Medicine/Molecular Imaging
Systems
vi. Diagnostic Ultrasound Systems
b. Imaging Contrast Agents and
Radiopharmaceuticals
i. X-Ray Contrast Media
ii. Magnetic Resonance Imaging
Contrast Media
iii. Nuclear Medicine/Molecular
Imaging Radiopharmaceuticals
c. Computer-Aided Detection
Systems
d. Less-Invasive Biopsy Products
i. Automated and Vacuum-Assisted
Breast Biopsy Devices
ii. Core Biopsy Needles and Delivery
Devices
e. Automated Papanicolaou Smear
Preparation/Screening Systems
f. Cancer Marker Testing Systems
Exhibit ES-1: Estimated New Cases,
Prevalence, and Deaths for Selected Types of Cancer
Exhibit ES-2: Diagnostic Oncology,
Procedure Volumes Forecast, 2005-2010
Exhibit ES-3: Diagnostic Oncology
Products, Market Forecast, 2005-2010
Exhibit ES-4: Diagnostic Imaging
Systems, Market Forecast, 2005-2010
Exhibit ES-5: Conventional X-Ray-Based
Imaging Systems, Market Forecast, 2005-2010
Exhibit ES-6: Mammography Systems,
Market Forecast, 2005-2010
Exhibit ES-7: Computed Tomography
Systems, Market Forecast, 2005-2010
Exhibit ES-8: Magnetic Resonance
Imaging Systems, Market Forecast, 2005-2010
Exhibit ES-9: Nuclear Medicine/Molecular
Imaging Systems, Market Forecast, 2005-2010
Exhibit ES-10: Diagnostic Ultrasound
Systems, Market Forecast, 2005-2010
Exhibit ES-11: Contrast-Enhanced
Diagnostic Oncology Imaging, Procedure Volumes Forecast, 2005-2010
Exhibit ES-12: Diagnostic Oncology-Related
Contrast Agents and Radiopharmaceuticals, Market Forecast,
2005-2010
Exhibit ES-13: Oncology-Related Conventional
X-Ray and Computed Tomography Imaging Contrast Agents, Market
Forecast, 2005-2010
Exhibit ES-14: Oncology-Related Magnetic
Resonance Imaging Contrast Agents, Market Forecast, 2005-2010
Exhibit ES-15: Oncology-Related Nuclear
Medicine/Molecular Imaging Radiopharmaceuticals, Market Forecast,
2005-2010
Exhibit ES-16: Standalone Computer-Aided
Detection Systems for Oncology Applications, Market Forecast,
2005-2010
Exhibit ES-17: Oncology-Related Less-Invasive
Tissue Biopsy, Procedure Volumes Forecast, 2005-2010
Exhibit ES-18: Oncology-Related Less-Invasive
Tissue Biopsy Systems, Market Forecast, 2005-2010
Exhibit ES-19: Automated and Vacuum-Assisted
Breast Biopsy Devices, Market Forecast, 2005-2010
Exhibit ES-20: Core Biopsy Needle
Products, Market Forecast, 2005-2010
Exhibit ES-21: Automated Papanicolaou
Smear Preparation/Screening Systems, Market Forecast, 2005-2010
Exhibit ES-22: Cancer Marker Testing
Products, Market Forecast, 2005-2010
1.
CANCER ETIOLOGY AND EPIDEMIOLOGY
1.1
Acquired Capabilities of Cancer Cells
1.2 Cataloging Genomic Alterations
Involved in the Development of Cancer
1.3 Risk Factors Associated with the
Development of Cancer
1.4 Cancer Staging
1.5 New Cancer Cases, Cancer Prevalence,
and Deaths Due to Cancer
1.6 Clinical and Statistical Data
for Selected Types of Cancer
1.6.1 Brain and Other Nervous System Cancers
1.6.1.1 Etiology
1.6.1.2 Epidemiology
1.6.2 Breast Cancer
1.6.2.1 Etiology
1.6.2.2 Epidemiology
1.6.3 Colorectal Cancer
1.6.3.1 Etiology
1.6.3.2 Epidemiology
1.6.4 Leukemia
1.6.4.1 Etiology
1.6.4.2 Epidemiology
1.6.5 Lung/Bronchus Cancer
1.6.5.1 Etiology
1.6.5.2 Epidemiology
1.6.6 Lymphoma
1.6.6.1 Etiology
1.6.6.2 Epidemiology
1.6.7 Melanoma
1.6.7.1 Etiology
1.6.7.2 Epidemiology
1.6.8 Oral Cavity and Pharyngeal Cancers
1.6.8.1 Etiology
1.6.8.2 Epidemiology
1.6.9 Ovarian Cancer
1.6.9.1 Etiology
1.6.9.2 Epidemiology
1.6.10 Pancreatic Cancer
1.6.10.1 Etiology
1.6.10.2 Epidemiology
1.6.11 Prostate Cancer
1.6.11.1 Etiology
1.6.11.2 Epidemiology
1.6.12 Urinary Bladder Cancer
1.6.12.1 Etiology
1.6.12.2 Epidemiology
1.6.13 Uterine Cancer
1.6.13.1 Etiology
1.6.13.2 Epidemiology
Exhibit 1-1: Estimated New Cases,
Prevalence, and Deaths for Selected Types of Cancer
Exhibit 1-2: Brain and Other
Nervous System Cancers, Facts And Figures
Exhibit 1-3: Breast Cancer, Facts
And Figures
Exhibit 1-4: Colorectal Cancer,
Facts And Figures
Exhibit 1-5: Leukemia, Facts
and Figures
Exhibit 1-6: Lung/Bronchus Cancer,
Facts And Figures
Exhibit 1-7: Hodgkin Lymphoma,
Facts and Figures
Exhibit 1-8: Non-Hodgkin Lymphoma,
Facts and Figures
Exhibit 1-9: Melanoma, Facts
and Figures
Exhibit 1-10: Oral Cavity and Pharyngeal
Cancers, Facts and Figures
Exhibit 1-11: Ovarian Cancer, Facts
and Figures
Exhibit 1-12: Pancreatic Cancer,
Fact and Figures
Exhibit 1-13: Prostate Cancer,
Facts And Figures
Exhibit 1-14: Urinary Bladder Cancer,
Fact and Figures
Exhibit 1-15: Cancer of the Uterine
Corpus, Facts and Figures
Exhibit 1-16: Cancer of the Uterine
Cervix, Facts and Figures
2. DIAGNOSTIC ONCOLOGY TECHNIQUES
AND PROCEDURES
2.1
Diagnostic Imaging
2.1.1 Conventional X-Ray Imaging
2.1.1.1 Contrast Media
2.1.1.2 Computed Radiography and Digital
Radiography
2.1.1.3 General Radiology/Fluoroscopy
2.1.1.4 Conventional X-Ray-Based Imaging,
Oncology-Related Applications
2.1.1.5 Conventional X-Ray-Based Imaging,
Procedure Volumes
2.1.2 Mammography
2.1.2.1 Digital Mammography
2.1.2.2 Computer-Aided Detection in
Mammograph
2.1.2.3 Mammography, Procedure Volumes
2.1.3 Computed Tomography
2.1.3.1 Spiral Computed Tomography
2.1.3.2 Multislice Computed Tomography
2.1.3.3 Computed Tomography, Oncology-Related
Applications
2.1.3.4 Computed Tomography, Procedure
Volumes
2.1.4 Magnetic Resonance Imaging
2.1.4.1 Functional Magnetic Resonance Imaging
2.1.4.2 Proton Magnetic Resonance
Spectroscopy
2.1.4.3 Interventional Magnetic Resonance
2.1.4.4 Contrast Media
2.1.4.5 Magnetic Resonance Imaging,
Oncology-Related Applications
2.1.4.6 Magnetic Resonance Imaging,
Procedure Volumes
2.1.5 Nuclear Medicine/Molecular Imaging
2.1.5.1 Gamma Camera Imaging
2.1.5.2 Positron Emission Tomography
Scanner Imaging
2.1.5.3 Fusion Imaging Techniques
2.1.5.4 Radioimmunoscintigraphy
2.1.5.5 Nuclear Medicine/Molecular
Imaging, Oncology-Related Applications
2.1.5.6 Nuclear Medicine/Molecular
Imaging, Procedure Volumes
2.1.6 Diagnostic Ultrasound
2.1.6.1 Doppler Imaging
2.1.6.2 Duplex Ultrasonography
2.1.6.3 Contrast Media
2.1.6.4 Diagnostic Ultrasound, Oncology-Related
Applications
2.1.6.5 Diagnostic Ultrasound, Procedure
Volumes
2.1.7 Computer-Aided Detection
2.1.7.1 Computer-Aided Detection in
Mammography-Based Breast Cancer Screening
2.1.7.2 Computer-Aided Detection in
Early-Stage Lung Cancer Diagnostics
2.1.7.3 Computer-Aided Detection in
Colorectal Cancer Diagnostics
2.1.8 Other Imaging Techniques
2.1.8.1 Electrical Impedance Scanning
2.1.8.2 Native Tissue Fluorescence/Opto-Electronic
Spectroscopy
2.2
In Vitro Diagnostic Techniques
2.2.1 Tumor Tissue Biopsy
2.2.1.1 Tissue Biopsy Methods
2.2.1.1.1 Fine Needle Aspiration Biopsy
2.2.1.1.2 Core Needle Biopsy
2.2.1.1.3 Endoscopic Biopsy
2.2.1.1.4 Punch Biopsy
2.2.1.1.5 Surgical Biopsy
2.2.1.1.6 Tumor Tissue Biopsy, Procedure
Volumes
2.2.2 Cancer Marker Testing
2.2.2.1 Tumor-Associated Markers
2.2.2.1.1 Alpha-Fetoprotein
2.2.2.1.2 Beta-Human Chorionic Gonadotropin
2.2.2.1.3 Bladder Tumor-Associated
Antigen
2.2.2.1.4 Cancer Antigen 15-3
2.2.2.1.5 Cancer Antigen 19-9
2.2.2.1.6 Cancer Antigen 27-29
2.2.2.1.7 Cancer Antigen 125
2.2.2.1.8 Carcinoembryonic Antigen
2.2.2.1.9 Neuron-Specific Enolase
2.2.2.1.10 Prostate-Specific Antigen
2.2.2.1.11 Prostatic Acid Phosphatase
2.2.2.1.12 Selected Breast Cancer
Markers
2.2.2.1.13 Selected Lung Cancer Markers
2.2.2.2 Genetic Cancer Markers
2.2.2.2.1 APC
2.2.2.2.2 ATM
2.2.2.2.3 BCL2
2.2.2.2.4 BIRC2 and BIRC4
2.2.2.2.5 BRCA1 and BRCA2
2.2.2.2.6 ERBB2
2.2.2.2.7 ER and PR
2.2.2.2.8 GADD45A
2.2.2.2.9 KLK2
2.2.2.2.10 PCNA
2.2.2.2.11 PMS2
2.2.2.2.12 RB1
2.2.2.2.13 SPP1
2.2.2.2.14 TP53
2.2.2.3 Developments in Site-Specific
Cancer Markers
2.2.2.3.1 Bladder Cancer
2.2.2.3.2 Breast Cancer
2.2.2.3.3 Colorectal Cancer
2.2.2.3.4 Endometrial and Cervical
Cancers
2.2.2.3.5 Esophageal Cancer
2.2.2.3.6 Hepatic Cancer
2.2.2.3.7 Lung Cancer
2.2.2.3.8 Ovarian Cancer
2.2.2.3.9 Pancreatic Cancer
2.2.2.3.10 Prostate Cancer
2.2.2.3.11 Telomerase-Based Universal
Cancer Markers
2.2.2.4 Advanced Biomolecular Technologies
for Cancer Detection and Profiling
2.2.2.4.1 Immunohistochemical Analysis
2.2.2.4.2 Microarray Expression Analysis
2.2.2.4.3 Polymerase Chain Reaction
Technology
2.2.2.4.4 Serial Analysis of Gene
Expression
2.2.2.4.5 Surface-Enhanced Laser Desorption/Ionization
2.2.2.5 Cancer Chemosensitivity Testing
2.2.2.6 Cancer Marker Testing, Procedure
Volumes
2.2.3 Cancer Screening
2.2.3.1 Fecal Occult Blood Testing
2.2.3.2 Helicobacter Pylori Testing
2.2.3.3 Human Papillomavirus Testing
2.2.3.4 Papanicolaou Smear Testing
2.2.3.5 Cancer Screening, Procedure
Volumes
Exhibit 2-1: Diagnostic Oncology,
Procedure Volumes Forecast, 2005-2010
Exhibit 2-2: United States, Selected
Population Statistics, 2000, 2010, 2020, and 2030
Exhibit 2-3: Conventional X-Ray-Based
Imaging, Procedure Volumes Forecast, 2005-2010
Exhibit 2-4: Mammography, Procedure
Volumes Forecast, 2005-2010
Exhibit 2-5: Computed Tomography,
Procedure Volumes Forecast, 2005-2010
Exhibit 2-6: Magnetic Resonance
Imaging, Procedure Volumes Forecast, 2005-2010
Exhibit 2-7: Nuclear Medicine/Molecular
Imaging, Procedure Volumes Forecast, 2005-2010
Exhibit 2-8: Diagnostic Ultrasound,
Procedure Volumes Forecast, 2005-2010
Exhibit 2-9: Tumor Tissue Biopsy,
Procedure Volumes Forecast, 2005-2010
Exhibit 2-10: 2007, Selected Tumor
Markers
Exhibit 2-11: 2007, Selected Genetic
Cancer Markers
Exhibit 2-12: Cancer Marker Testing,
Procedure Volumes Forecast, 2005-2010
Exhibit 2-13: Cancer Screening,
Procedure Volumes Forecast, 2005-2010
3.
DIAGNOSTIC ONCOLOGY PRODUCTS MARKET
3.1
Diagnostic Imaging Platforms
3.1.1 Conventional X-Ray-Based Imaging Systems
3.1.1.1 Products
3.1.1.2 Market Forecast
3.1.1.3 Competitive Analysis
3.1.2 Mammography Systems
3.1.2.1 Products
3.1.2.2 Market Forecast
3.1.2.3 Competitive Analysis
3.1.3 Computed Tomography Systems
3.1.3.1 Products
3.1.3.2 Market Forecast
3.1.3.3 Competitive Analysi
3.1.4 Magnetic Resonance Imaging Systems
3.1.4.1 Products
3.1.4.2 Market Forecast
3.1.4.3 Competitive Analysis
3.1.5 Nuclear Medicine/Molecular Imaging Systems
3.1.5.1 Products
3.1.5.2 Market Forecast
3.1.5.3 Competitive Analysis
3.1.6 Diagnostic Ultrasound Systems
3.1.6.1 Products
3.1.6.2 Market Forecast
3.1.6.3 Competitive Analysis
3.2
Imaging Contrast Agents and Radiopharmaceuticals
3.2.1 X-Ray Contrast Media
3.2.1.1 Products
3.2.1.2 Market Forecast
3.2.1.3 Competitive Analysis
3.2.2 Magnetic Resonance Imaging Contrast Media
3.2.2.1 Products
3.2.2.2 Market Forecast
3.2.2.3 Competitive Analysis
3.2.3 Nuclear Medicine/Molecular Imaging
Radiopharmaceuticals
3.2.3.1 Products
3.2.3.2 Market Forecast
3.2.3.3 Competitive Analysis
3.3
Computer-Aided Detection Systems
3.3.1 Products
3.3.2 Market Forecast
3.3.3 Competitive Analysis
3.4
Less-Invasive Biopsy Products
3.4.1 Automated and Vacuum-Assisted
Breast Biopsy Devices
3.4.1.1 Products
3.4.1.2 Market Forecast
3.4.1.3 Competitive Analysis
3.4.2 Core Biopsy Needles and Delivery
Devices
3.4.2.1 Products
3.4.2.2 Market Forecast
3.4.2.3 Competitive Analysis
3.5 Automated Papanicolaou Smear Preparation/Screening
Systems
3.5.1 Products
3.5.2 Market Forecast
3.5.3 Competitive Analysis
3.6
Cancer Marker Testing Systems
3.6.1 Products
3.6.2 Market Forecast
3.6.3 Competitive Analysis
Exhibit 3-1: Oncology-Related
Diagnostic Examinations, Procedure Volumes Forecast, 2005-2010
Exhibit 3-2: Diagnostic Oncology
Products, Market Forecast, 2005-2010
Exhibit 3-3: Diagnostic Imaging,
Procedure Volumes Forecast, 2005-2010
Exhibit 3-4: Diagnostic Imaging
Systems, Market Forecast, 2005-2010
Exhibit 3-5: 2007, Selected Conventional
X-Ray-Based Imaging Systems
Exhibit 3-6: Conventional X-Ray-Based
Imaging Systems, Market Forecast, 2005-2010
Exhibit 3-7: 2006, Conventional
X-Ray-Based Imaging Systems Market, Share by Supplier
Exhibit 3-8: 2007, Selected Mammography
Systems
Exhibit 3-9: Mammography Systems,
Market Forecast, 2005-2010
Exhibit 3-10: 2006, Mammography
Systems Market, Share by Supplier
Exhibit 3-11: 2007, Selected Computed
Tomography Systems
Exhibit 3-12: Computed Tomography
Systems, Market Forecast, 2005-2010
Exhibit 3-13: 2006, Computed Tomography
Systems Market, Share by Supplier
Exhibit 3-14: 2007, Selected Magnetic
Resonance Imaging Systems
Exhibit 3-15: Magnetic Resonance
Imaging Systems, Market Forecast, 2005-2010
Exhibit 3-16: 2006, Magnetic Resonance
Imaging Systems Market, Share by Supplier
Exhibit 3-17: 2007, Selected Nuclear
Medicine/Molecular Imaging Systems
Exhibit 3-18: Nuclear Medicine/Molecular
Imaging Systems, Market Forecast, 2005-2010
Exhibit 3-19: 2006, Nuclear Medicine/Molecular
Imaging Systems Market, Share by Supplier
Exhibit 3-20: 2007, Selected Diagnostic
Ultrasound Systems
Exhibit 3-21: Diagnostic Ultrasound
Systems, Market Forecast, 2005-2010
Exhibit 3-22: 2006, Diagnostic
Ultrasound Systems Market, Share by Supplier
Exhibit 3-23: Contrast-Enhanced
Diagnostic Oncology Imaging, Procedure Volumes Forecast, 2005-2010
Exhibit 3-24: Diagnostic Oncology-Related
Contrast Agents and Radiopharmaceuticals, Market Forecast, 2005-2010
Exhibit 3-25: Oncology-Related
Conventional X-Ray and Computed Tomography Imaging Contrast
Agents, Market Forecast, 2005-2010
Exhibit 3-26: 2006, Oncology-Related
Conventional X-Ray-Based Imaging and Computed Tomography Contrast
Agents Market, Share by Supplier
Exhibit 3-27: Oncology-Related
Magnetic Resonance Imaging Contrast Agents, Market Forecast,
2005-2010
Exhibit 3-28: 2006, Oncology-Related
Magnetic Resonance Imaging Contrast Agents Market, Share by
Supplier
Exhibit 3-29: Oncology-Related
Nuclear Medicine/Molecular Imaging Radiopharmaceuticals, Market
Forecast, 2005-2010
Exhibit 3-30: 2006, Gamma Camera-Based
Nuclear Medicine/Molecular Imaging Radiopharmaceuticals Market,
Share by Supplier
Exhibit 3-31: 2006, Positron Emission
Tomography-Based Nuclear Medicine/Molecular Imaging Radiopharmaceuticals
Market, Share by Supplier
Exhibit 3-32: 2007, Selected Computer-Aided
Detection Systems
Exhibit 3-33: Standalone Computer-Aided
Detection Systems for Oncology Applications, Market Forecast,
2005-2010
Exhibit 3-34: 2006, Standalone
Computer-Aided Detection Systems Market, Share by Supplier
Exhibit 3-35: Oncology-Related
Less-Invasive Tissue Biopsy, Procedure Volumes Forecast, 2005-2010
Exhibit 3-36: Oncology-Related
Less-Invasive Tissue Biopsy Systems, Market Forecast, 2005-2010
Exhibit 3-37: 2007, Selected Automated
and Vacuum-Assisted Breast Biopsy Devices
Exhibit 3-38: Automated and Vacuum-Assisted
Breast Biopsy Devices, Market Forecast, 2005-2010
Exhibit 3-39: 2006, Automated and
Vacuum-Assisted Breast Biopsy Devices Market, Share by Supplier
Exhibit 3-40: Core Biopsy Needle
Products, Market Forecast, 2005-2010
Exhibit 3-41: 2006, Core Biopsy
Needles and Delivery Devices Market, Share by Supplier
Exhibit 3-42: 2007, Selected Automated
Papanicolaou Smear Preparation/Screening Systems
Exhibit 3-43: Automated Papanicolaou
Smear Preparation/Screening Systems, Market Forecast, 2005-2010
Exhibit 3-44: 2006, Automated Papanicolaou
Smear Preparation/Screening Systems Market, Share by Supplier
Exhibit 3-45: Cancer Marker Testing
Products, Market Forecast, 2005-2010
Exhibit 3-46: 2006, Cancer Marker
Testing Products Market, Share by Supplier
4.
COMPANY PROFILES
4.1
Abbott Diagnostics/Abbott Laboratories
4.2
C. R. Bard, Inc.
4.3 Bayer HealthCare Pharmaceuticals,
Inc./Bayer HealthCare LLC/ Bayer AG
4.4
Bracco Diagnostics, Inc./Bracco Group
4.5 Bristol-Myers Squibb Company
4.6 Cardinal Health, Inc.
4.7 Cytyc Corporation
4.8 Digene Corporation/QIAGEN
NV
4.9 Ethicon Endo-Surgery, Inc./Johnson
& Johnson
4.10 GE Healthcare/General Electric
Company
4.11 Hologic, Inc.
4.12 iCAD, Inc.
4.13 Mallinckrodt, Inc./Covidien
LTD
4.14 Philips Medical Systems,
Inc./Royal Philips Electronics NV
4.15 Siemens Medical Solutions/Siemens
AG
APPENDIX:
COMPANY LISTING