In 2005, nearly $1.1 billion was spent on neurosurgical and neurointerventional surgical products in the United States.  Growing at a healthy compound annual rate of 4.1%, sales of these products are expected to reach more than $1.4 billion by the year 2012.

This dynamic report from Medtech Insight includes analyses of products, technologies, current and forecast markets, competitors, and opportunities in the U.S. neurosurgery products market and the minimally invasive neurointerventional surgery products market.  These products are used to treat a wide range of debilitating neurological disorders including Alzheimer’s disease, Parkinson’s disease, stroke, cerebral aneurysms, tumors, hydrocephalus, and arteriovenous malformations.  Disorders of the nervous system comprise one of the major categories of human disease, accounting for more than 2.8 million hospital admissions annually and afflicting more than 12 million individuals in the U.S.  In all, there are more than 1,000 disorders of the brain and nervous system, afflicting 1 out of 5 people in the U.S. 

Covered topics in this report include cranial repair and closure devices, electrosurgery systems, surgical implants (including aneurysm clips and hydrocephalus shunts and valves), surgical instruments (handheld and powered), surgical navigation systems (including image-guided and stereotactic devices), and ultrasonic aspiration systems.  Other products covered include minimally invasive devices such as catheters, coils, embolic agents, guidewires, neuroendoscopes, and stents and products for brachytherapy and radiotherapy procedures.

TABLE OF CONTENTS AND LIST OF EXHIBITS

EXECUTIVE SUMMARY

i.   Overview of Selected Neurologic Disorders

ii.   Neurosurgical Devices Market

a.  Market Analysis

iii.  Minimally Invasive Neurointerventional Devices Market

a.  Market Analysis

iv.  Image-Guided and Stereotactic Surgical Navigation Systems

a.  Market Analysis

v.  Radiosurgery Systems

a.  Market Analysis

vi.  Combined Market Analysis

Exhibit ES-1:  2005, Incidence of Selected Neurologic Diseases/Disorders

Exhibit ES-2:  Open Neurosurgical Devices, Combined Market Forecast, 2005-2012

Exhibit ES-3:  Minimally Invasive Neurointerventional Devices, Combined Market Forecast, 2005-2012

Exhibit ES-4:  Image-Guided and Stereotactic Surgical Systems, Market Forecast, 2005-2012

Exhibit ES-5:  Radiosurgery Systems, Market Forecast, 2005-2012

Exhibit ES-6:  Neurosurgical, Neurointerventional, and Image-Guided and Stereotactic Surgical Navigation Products, Combined Market Forecast, 2005-2012

1. CLINICAL AND TREATMENT OVERVIEW

1.1 Overview of the Nervous System

1.1.1 The Brain and Cerebrovascular System

1.1.2 The Peripheral Nervous System

1.2 Neurologic Disorders

1.2.1 Alzheimer’s Disease

1.2.1.1 Etiology

1.2.1.2 Incidence

1.2.1.3 Prevalence

1.2.1.4 Treatment Options

1.2.1.4.1 Device-Based Therapy

1.2.1.4.2 Drug Therapy

1.2.1.4.3 Surgery

1.2.1.5 Prevention

1.2.2 Parkinson’s Disease

1.2.2.1 Etiology

1.2.2.2 Incidence

1.2.2.3 Prevalence

1.2.2.4 Treatment Options

1.2.2.4.1 Device-Based Therapy

1.2.2.4.2 Drug Therapy

1.2.2.4.3 Surgery

1.2.2.4.4 Other

1.2.2.5 Prevention

1.2.3 Stroke

1.2.3.1 Etiology

1.2.3.2 Incidence

1.2.3.3 Prevalence

1.2.3.4 Treatment Options

1.2.3.4.1 Device-Based Therapy

1.2.3.4.2 Drug Therapy

1.2.3.5 Prevention

1.2.4 Cerebral Aneurysm

1.2.4.1 Etiology

1.2.4.2 Incidence

1.2.4.3 Prevalence

1.2.4.4 Treatment Options

1.2.4.4.1 Device-Based Therapy

1.2.4.4.2 Drug Therapy

1.2.4.4.3 Surgery

1.2.4.4.4 Other

1.2.5 Arteriovenous Malformations

1.2.5.1 Etiology

1.2.5.2 Incidence

1.2.5.3 Prevalence

1.2.5.4 Treatment Options

1.2.5.4.1 Device-Based Therapy

1.2.5.4.2 Drug Therapy

1.2.5.4.3 Surgery

1.2.5.4.4 Radiation Therapy

1.2.6 Tumors of the Brain or Central Nervous System

1.2.6.1 Etiology

1.2.6.2 Incidence

1.2.6.3 Prevalence

1.2.6.4 Treatment Options

1.2.6.4.1 Device-Based Therapy

1.2.6.4.2 Drug Therapy

1.2.6.4.3 Surgery

1.2.6.4.4 Other

1.2.7 Head Trauma

1.2.7.1 Etiology

1.2.7.2 Incidence

1.2.7.3 Prevalence

1.2.7.4 Treatment Options

1.2.7.4.1 Device-Based Therapy

1.2.7.4.2 Drug Therapy

1.2.7.4.3 Surgery

1.2.8 Hydrocephalus and Increased Intracranial Pressure

1.2.8.1 Etiology

1.2.8.2 Incidence

1.2.8.3 Prevalence

1.2.8.4 Treatment Options

1.2.8.4.1 Device-Based Therapy

1.2.8.4.2 Drug Therapy

1.2.8.4.3 Surgery

1.2.8.4.4 Other

Exhibit 1-1: Anatomy of the Brain

Exhibit 1-2: 2005, Alzheimer’s Disease, Facts and Figures

Exhibit 1-3: 2005, Parkinson’s Disease, Facts and Figures

Exhibit 1-4: Stroke, Incidence, 2005-2012

Exhibit 1-5: Incidence of Cerebral Aneurysms Requiring Intervention, 2005-2012

Exhibit 1-6: Hydrocephalus, Incidence, 2005-2012

2. NEUROSURGICAL DEVICES MARKET

2.1 Products/Technologies

2.1.1 Surgical Instruments

2.1.1.1 Handheld Instruments

2.1.1.1.1 Products/Technologies

2.1.1.1.2 Market Forecast

2.1.1.2 Powered Instruments and Accessories

2.1.1.2.1 Products/Technologies

2.1.1.2.2 Market Forecast

2.1.1.2.3 Competitive Analysis

2.1.1.3 Electrosurgical Systems

2.1.1.3.1 Products/Technologies

2.1.1.3.2 Market Forecast

2.1.1.4 Ultrasonic Aspiration Systems

2.1.1.4.1 Products/Technologies

2.1.1.4.2 Market Forecast

2.1.1.4.3 Competitive Analysis

2.1.2 Surgical Implants

2.1.2.1 Aneurysm Clips

2.1.2.1.1 Products/Technologies

2.1.2.1.2 Market Forecast

2.1.2.1.3 Competitive Analysis

2.1.2.2 Hydrocephalus Shunts and Valves

2.1.2.2.1 Products/Technologies

2.1.2.2.1.1 Implantable Cerebrospinal Fluid Shunts

2.1.2.2.1.2 External Cerebrospinal Fluid Drainage Systems

2.1.2.2.2 Market Forecast

2.1.2.2.3 Competitive Analysis

2.1.2.3 Cranial Repair and Closure Devices

2.1.2.3.1 Products/Technologies

2.1.2.3.1.1 Cranial Fixation and other Skull Closure Devices

2.1.2.3.1.2 Bone Cement and Bone Substitute Materials

2.1.2.3.1.3 Dura Mater Implants

2.1.2.3.2 Market Forecast

2.2 Open Neurosurgical Products, Combined Market Forecast

Exhibit 2-1:    Indications for Handheld Neurosurgical Instruments

Exhibit 2-2:    Craniotomy Tray, Representative Instruments

Exhibit 2-3:    2006, Selected Handheld Neurosurgical Instruments

Exhibit 2-4:    Handheld Neurosurgical Instruments, Market Forecast, 2005-2012

Exhibit 2-5:    Powered Neurosurgical Instruments

Exhibit 2-6:    2006, Selected Powered Neurosurgical Instruments

Exhibit 2-7:    Powered Neurosurgical Instruments, Market Forecast, 2005-2012

Exhibit 2-8:    2005, Powered Neurosurgical Instruments Market,  Share by Supplier

Exhibit 2-9:    2006, Selected Electrosurgical Products

Exhibit 2-10:  Electrosurgical Products for Neurosurgical Applications, Market Forecast, 2005-2012

Exhibit 2-11:  2006, Selected Ultrasonic Aspiration Products

Exhibit 2-12:  Ultrasonic Aspiration Products for Neurosurgical Applications, Market Forecast, 2005-2012

Exhibit 2-13:  2005, Ultrasonic Aspiration Products Market, Share by Supplier

Exhibit 2-14:  2006, Selected Aneurysm Clip Products

Exhibit 2-15:  Aneurysm Clips for Neurosurgical Applications, Market Forecast, 2005-2012

Exhibit 2-16:  2005, Aneurysm Clips Market, Share by Supplier

Exhibit 2-17:  Hydrocephalus Valve Implants, Typical Pressure/Flow Relationships

Exhibit 2-18:  2006, Selected Implantable Hydrocephalus Treatment Products

Exhibit 2-19:  2006, Selected Lumbar Valve and Shunt Implant Products for Hydrocephalus Treatment

Exhibit 2-20:  2006, Selected External Cerebrospinal Fluid Drainage Products

Exhibit 2-21:  Shunts, Valves, and External Cerebral Spinal Fluid Drainage Products, Market Forecast, 2005-2012

Exhibit 2-22:  2005, Shunts, Valves, and External Cerebral Spinal Fluid Drainage Products Market, Share by Supplier

Exhibit 2-23:  2006, Selected Cranial Fixation and Cranioplasty Products

Exhibit 2-24:  2006, Selected Dura Mater Substitutes

Exhibit 2-25:  Cranial Fixation Devices, Dura Mater Substitutes, and Other Cranial Repair Products, Market Forecast, 2005-2012

Exhibit 2-26:  Open Neurosurgical Devices, Combined Market Forecast, 2005-2012

Exhibit 2-27:  2005, Open Neurosurgical Devices Market, Share by Market Segment

3. MINIMALLY INVASIVE NEUROINTERVENTIONAL DEVICES MARKET

3.1 Overview

3.2 Technologies

3.3 Vascular Access and Catheter Guidance

3.3.1 Products/Technologies

3.3.2 Market Forecast

3.4 Coils and Embolic Agents

3.4.1 Products/Technologies

3.4.2 Market Forecast

3.5 Stents

3.5.1 Peripheral Neurovascular Stents for the Prevention of Ischemic Strokes

3.5.1.1 Products/Technologies

3.5.1.2 Market Forecast

3.5.2 Neurovascular Stents for the Containment  of Embolic Coils in Wide-Neck Aneurysms

3.5.3 Products/Technologies

3.5.4 Market Forecast

3.6 Neuroendoscopic Surgery

3.6.1 Products/Technologies

3.6.2 Market Forecast

3.7 Thrombectomy

3.8 Minimally Invasive Neurointerventional Devices Combined Market Forecast

3.9 Competitive Analysis

Exhibit 3-1:    2006, Selected Neurointerventional Microcatheters and Microguidewires

Exhibit 3-2:    Neurointerventional Catheter Products, Market Forecast, 2005-2012

Exhibit 3-3:    Neurointerventional Guidewire Products, Market Forecast, 2005-2012

Exhibit 3-4:    2006, Selected Neurointerventional Embolic Coil Products

Exhibit 3-5:    2006, Selected Liquid Embolic Products

Exhibit 3-6:    Neurointerventional Embolic Coil Products, Market Forecast, 2005-2012

Exhibit 3-7:    2006, Selected Neurointerventional Stent Products

Exhibit 3-8:    Boston Scientific’s Stent Systems

Exhibit 3-9:    Neurointerventional Stent Systems for the Treatment of Ischemic Stroke, Market Forecast, 2005-2012

Exhibit 3-10:  Neurointerventional Embolic Coil-Containment Stent Systems, Market Forecast, 2005-2012

Exhibit 3-11:  Selected Neuroendoscopic Techniques

Exhibit 3-12:  2006, Selected Neuroendoscopes

Exhibit 3-13:  Selected Neuroendoscope Product Images

Exhibit 3-14:  Neuroendoscopes, U.S. Market Forecast, 2005-2012

Exhibit 3-15:  Minimally Invasive Neurointerventional Devices, Combined Market Forecast, 2005-2012

Exhibit 3-16:  2005, Minimally Invasive Neurointerventional Devices Market, Share by Supplier

4.IMAGE-GUIDED AND STEREOTACTIC SURGICAL NAVIGATION SYSTEMS

4.1 Image-Guided Surgical Navigation Systems

4.1.1 Products/Technologies

4.2 Stereotactic Surgical Navigation Systems

4.2.1 Frame-Based Stereotactic Systems

4.2.1.1 Products/Technologies

4.3 Image-Guided and Stereotactic Surgical Systems Market Forecast

4.4 Image-Guided and Stereotactic Surgical Systems Competitive Analysis

4.5 Radiosurgery Systems

4.5.1 Products/Technologies

4.5.1.1 The Gamma Knife

4.5.1.2 Linear Accelerator-Based Systems

4.5.1.3 Other

4.5.1.3.1 Miniaturized X-Ray Tube Technology

4.5.1.3.2 Proton Beam Radiation

4.5.2 Radiosurgery Systems Market Forecast

4.5.3 Radiosurgery Systems Competitive Analysis

4.6 Brachytherapy

4.6.1 Products/Technologies

4.7 Robotics

Exhibit 4-1:    Medtronic’s StealthStation TRIA Plus Image-Guided Surgical Navigation System

Exhibit 4-2:    2006, Selected Image-Guided Neurosurgical Navigation Systems

Exhibit 4-3:    2006, Selected Mechanical Stereotactic Systems

Exhibit 4-4:    Image-Guided and Stereotactic Surgical Systems, Market Forecast, 2005-2012

Exhibit 4-5:    2005, Image-Guided and Stereotactic Surgical Systems Market, Share by Supplier

Exhibit 4-6:    Selected Radiosurgery System Product Images

Exhibit 4-7:    2006, Selected Radiosurgery Systems

Exhibit 4-8:    Radiosurgery Systems, Market Forecast, 2005-2012

Exhibit 4-9:    2005, Radiosurgery Systems Market, Share by Supplier

Exhibit 4-10:  2006, Selected Brachytherapy Systems

Exhibit 4-11:  Prosurgics’ PathFinder Robotic System

Exhibit 4-12:  2006, Selected Robotic Systems

5. COMPANY PROFILES

5.1     Accuray, Inc.

5.2     Anspach, Inc.

5.3     B. Braun Melsungen AG

5.4     Boston Scientific, Inc.

5.5     BrainLAB AG

5.6     Elekta AB

5.7     ev3, Inc.

5.8     Integra LifeSciences Holdings Corporation

5.9     Johnson & Johnson, Inc.

5.10    Medtronic, Inc.

5.11    Micrus Endovascular Corporation

5.12    Mizuho Ikakogyo Co., LTD

5.13    Stryker Corporation

5.14    Terumo Corporation

5.15    Tyco International LTD

APPENDIX:  COMPANY LISTING

Copyright 2006, Medtech Insight, LLC