Major diseases in Europe––from cancer and cardiovascular disease to neurologic and psychiatric disorders––take their toll in terms of lost days from work, hospital expenditures, and out-of-pocket costs. As the aging population in Europe increases and life spans lengthen, the incidence and prevalence of major diseases/disorders are expected to significantly impact the European healthcare industry.

This dynamic new report from Medtech Insight examines the etiology and epidemiology of the most prevalent and costly diseases/disorders in Europe such as Alzheimer’s disease, anemia, arthritis, asthma, benign prostatic hyperplasia, bronchitis, burns/wounds, cancer, cataracts, depression, diabetes, emphysema, erectile dysfunction, glaucoma, heart failure, human immunodeficiency virus/acquired immune deficiency syndrome, hypertension, infertility, multiple sclerosis, osteoporosis, pneumonia, spongiform encephalopathy, and stroke.

In addition to the proprietary data from Medtech Insight’s internal resources that are utilized in this report, many organizations have provided information including Alzheimer Europe, European Registries of Stroke Collaboration, Myasthenia Gravis Association, Organization for Economic Cooperation and Development, and the World Health Organization, among others.

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TABLE OF CONTENTS

INTRODUCTION

1. EUROPEAN HEALTHCARE OVERVIEW

1.1 The European Union

1.1.1 Adoption of a Common Currency

1.1.2 The Aging Population

1.2 Selected European National Healthcare Profiles

1.2.1 France

1.2.1.1 Healthcare Organization and Reform

1.2.1.2 Hospital Services

1.2.1.3 Medical Device Reimbursement

1.2.2 Germany

1.2.2.1 Healthcare Organization and Reform

1.2.2.2 Hospital Services

1.2.2.3 Medical Device Reimbursement

1.2.3 Italy

1.2.3.1 Healthcare Organization and Reform

1.2.3.2 Hospital Services

1.2.3.3 Medical Device Reimbursements

1.2.4 Spain

1.2.4.1 Healthcare Organization and Reform

1.2.4.2 Hospital Services

1.2.4.3 Medical Device Reimbursement

1.2.5 United Kingdom

1.2.5.1 Healthcare Organization and Reform

1.2.5.2 Hospital Services

1.2.5.3 Medical Device Reimbursement

1.2.6 Benelux Countries

1.2.6.1 Healthcare Organization and Reform

1.2.6.2 Hospital Services

1.2.6.3 Medical Device Reimbursement

1.2.7 Nordic Countries

1.2.7.1 Healthcare Organization and Reform

1.2.7.2 Hospital Services

1.2.7.3 Medical Device Reimbursement

Exhibit 1-1:      European Union, Population Statistics Comparison for the Years 1996, 2006, and 2016

Exhibit 1-2:      France, Selected National Healthcare Statistics

Exhibit 1-3:      Germany, Selected National Healthcare Statistics

Exhibit 1-4:      Italy, Selected National Healthcare Statistics

Exhibit 1-5:      Spain, Selected National Healthcare Statistics

Exhibit 1-6:      The United Kingdom, Selected National Healthcare Statistics

Exhibit 1-7:      Belgium, Selected National Healthcare Statistics

Exhibit 1-8:      The Netherlands, Selected National Healthcare Statistics

Exhibit 1-9:      Luxembourg, Selected National Healthcare Statistics

Exhibit 1-10:    Denmark, Selected National Healthcare Statistics

Exhibit 1-11:    Finland, Selected National Healthcare Statistics

Exhibit 1-12:    Iceland, Selected National Healthcare Statistics

Exhibit 1-13:    Norway, Selected National Healthcare Statistics

Exhibit 1-14:    Sweden, Selected National Healthcare Statistics

2. BLOOD DISORDERS:  ANEMIA AND HEMOPHILIA

2.1 Anemia

2.1.1 Iron Deficiency Anemia

2.1.1.1 Etiology

2.1.1.2 Epidemiology

2.1.2 Sickle Cell Anemia

2.1.2.1 Etiology

2.1.2.2 Epidemiology

2.1.3 Thalassemia

2.1.3.1 Etiology

2.1.3.2 Epidemiology

2.2 Hemophilia

2.2.1 Etiology

2.2.2 Epidemiology

Exhibit 2-1:      Europe, Iron Deficiency Anemia, Incidence and Prevalence, by Country

Exhibit 2-2:      Europe, Sickle Cell Anemia, Incidence and Prevalence, by Country

Exhibit 2-3:      Europe, Thalassemia, Prevalence, by Country

Exhibit 2-4:      Europe, Hemophilia, Incidence and Prevalence, by Country

3. CANCER

3.1 Bladder Cancer

3.1.1 Etiology

3.1.2 Epidemiology

3.2 Brain Tumors

3.2.1 Etiology

3.2.2 Epidemiology

3.3 Breast Cancer

3.3.1 Etiology

3.3.2 Epidemiology

3.4 Cervical/Uterine Cancer

3.4.1 Etiology

3.4.2 Epidemiology

3.5 Colon/Rectal Cancer

3.5.1 Etiology

3.5.2 Epidemiology

3.6 Leukemia

3.6.1 Etiology

3.6.2 Epidemiology

3.7 Lung Cancer

3.7.1 Etiology

3.7.2 Epidemiology

3.8 Lymphoma

3.8.1 Etiology

3.8.2 Epidemiology

3.9 Melanoma

3.9.1 Etiology

3.9.2 Epidemiology

3.10 Oral Cancer

3.10.1 Etiology

3.10.2 Epidemiology

3.11 Ovarian Cancer

3.11.1 Etiology

3.11.2 Epidemiology

3.12 Pancreatic Cancer

3.12.1 Etiology

3.12.2 Epidemiology

3.13 Prostate Cancer

3.13.1 Etiology

3.13.2 Epidemiology

3.14 Stomach Cancer

3.14.1 Etiology

3.14.2 Epidemiology

3.15 Testicular Cancer

3.15.1 Etiology

3.15.2 Epidemiology

Exhibit 3-1:      Europe, Bladder Cancer, Incidence, by Country

Exhibit 3-2:      Europe, Brain Tumors, Incidence and Prevalence, by Country

Exhibit 3-3:      Europe, Breast Cancer, Incidence, by Country

Exhibit 3-4:      Europe, Cervical/Uterine Cancer, Incidence, by Country

Exhibit 3-5:      Europe, Colon/Rectal Cancer, Incidence, by Country

Exhibit 3-6:      Europe, Leukemia, Incidence, by Country

Exhibit 3-7:      Europe, Lung Cancer, Incidence, by Country

Exhibit 3-8:      Europe, Lymphoma, Incidence, by Country

Exhibit 3-9:      Europe, Melanoma, Incidence, by Country

Exhibit 3-10:    Europe, Oral Cancer, Incidence and Prevalence, by Country

Exhibit 3-11:    Europe, Ovarian Cancer, Incidence and Prevalence, by Country

Exhibit 3-12:    Pancreatic Cancer, Treatment Options and Survival Rates, by Stage

Exhibit 3-13:    Europe, Pancreatic Cancer, Incidence, by Country

Exhibit 3-14:    Europe, Prostate Cancer, Incidence, by Country

Exhibit 3-15:    Europe, Stomach Cancer, Incidence, by Country

Exhibit 3-16:    Europe, Testicular Cancer, Incidence, by Country

4. CARDIOVASCULAR DISORDERS

4.1 Cardiac Arrhythmia

4.1.1 Etiology

4.1.2 Epidemiology

4.2 Heart Failure

4.2.1 Etiology

4.2.2 Epidemiology

4.3 Heart Valve Disorders

4.3.1 Etiology

4.3.2 Epidemiology

4.4 Hypertension

4.4.1 Etiology

4.4.2 Epidemiology

4.5 Vascular Disorders

4.5.1 Aneurysm

4.5.1.1 Etiology

4.5.1.2 Epidemiology

4.5.2 Atherosclerosis

4.5.2.1 Etiology

4.5.2.2 Epidemiology

4.5.3 Ischemic Heart Disease

4.5.3.1 Etiology

4.5.3.2 Epidemiology

4.5.4 Myocardial Infarction

4.5.4.1 Etiology

4.5.4.2 Epidemiology

4.5.5 Peripheral Vascular Disease

4.5.5.1 Etiology

4.5.5.2 Epidemiology

Exhibit 4-1:      Europe, Cardiac Arrhythmia, Prevalence, by Country

Exhibit 4-2:      Europe, Heart Failure, Incidence and Prevalence, by Country

Exhibit 4-3:      Europe, Heart Valve Disorders, Incidence and Prevalence, by Country

Exhibit 4-4:      Europe, Hypertension, Incidence and Prevalence, by Country

Exhibit 4-5:      Europe, Aneurysm, Prevalence, by Country

Exhibit 4-6:      Europe, Atherosclerosis, Prevalence, by Country

Exhibit 4-7:      Europe, Ischemic Heart Disease, Prevalence, by Country

Exhibit 4-8:      Europe, Myocardial Infarction, Incidence and Prevalence, by Country

Exhibit 4-9:      Europe, Peripheral Vascular Disease, Prevalence, by Country

5. METABOLIC DISORDERS

5.1 Cholelithiasis

5.1.1 Etiology

5.1.2 Epidemiology

5.2 Chronic Kidney Disease/End-Stage Renal Disease

5.2.1 Etiology

5.2.2 Epidemiology

5.3 Diabetes

5.3.1 Etiology

5.3.2 Epidemiology

5.4 Urolithiasis

5.4.1 Etiology

5.4.2 Epidemiology

Exhibit 5-1:      Europe, Cholelithiasis, Incidence and Prevalence, by Country

Exhibit 5-2:      Europe, End-Stage Renal Disease, Incidence and Prevalence, by Country

Exhibit 5-3:      Europe, Diabetes, Incidence and Prevalence, by Country

Exhibit 5-4:      Europe, Urolithiasis, Incidence and Prevalence, by Country

6. MUSCULOSKELETAL DISORDERS

6.1 Arthritis

6.1.1 Etiology

6.1.2 Epidemiology

6.2 Carpal Tunnel Syndrome

6.2.1 Etiology

6.2.2 Epidemiology

6.3 Meniscal and Ligament/Tendon Injuries

6.3.1 Etiology

6.3.2 Epidemiology

6.4 Duchenne Muscular Dystrophy

6.4.1 Etiology

6.4.2 Epidemiology

6.5 Osteoporosis

6.5.1 Etiology

6.5.2 Epidemiology

Exhibit 6-1:      Europe, Arthritis, Incidence and Prevalence, by Country

Exhibit 6-2:      Europe, Carpel Tunnel Syndrome, Incidence and Prevalence, by Country

Exhibit 6-3:      Europe, Meniscal and Ligament/Tendon Injuries, Incidence, by Country

Exhibit 6-4:      Europe, Duchenne Muscular Dystrophy, Incidence and Prevalence, by Country

Exhibit 6-5:      Europe, Osteoporosis, Incidence and Prevalence, by Country

7. NEUROLOGIC AND PSYCHIATRIC DISORDERS

7.1 Alzheimer’s Disease

7.1.1 Etiology

7.1.2 Epidemiology

7.2 Amyotrophic Lateral Sclerosis

7.2.1 Etiology

7.2.2 Epidemiology

7.3 Bipolar Disorder

7.3.1 Etiology

7.3.2 Epidemiology

7.4 Cerebrovascular Disorders

7.4.1 Arteriovenous Malformation

7.4.1.1 Etiology

7.4.1.2 Epidemiology

7.4.2 Stroke

7.4.2.1 Etiology

7.4.2.3 Epidemiology

7.5 Depression

7.5.1 Etiology

7.5.2 Epidemiology

7.6 Epilepsy

7.6.1 Etiology

7.6.2 Epidemiology

7.7 Huntington’s Disease

7.7.1 Etiology

7.7.2 Epidemiology

7.8 Hydrocephalus

7.8.1 Etiology

7.8.2 Epidemiology

7.9 Multiple Sclerosis

7.9.1 Etiology

7.9.2 Epidemiology

7.10 Myasthenia Gravis

7.10.1 Etiology

7.10.2 Epidemiology

7.11 Parkinson’s Disease

7.11.1 Etiology

7.11.2 Epidemiology

7.12 Schizophrenia

7.12.1 Etiology

7.12.2 Epidemiology

Exhibit 7-1:      Diagnosed Alzheimer’s Disease Population

Exhibit 7-2:      Europe, Alzheimer’s Disease, Incidence and Prevalence, by Country

Exhibit 7-3:      Europe, Amyotrophic Lateral Sclerosis, Incidence and Prevalence, by Country

Exhibit 7-4:      Europe, Bipolar Disorder, Prevalence, by Country

Exhibit 7-5:      Europe, Arteriovenous Malformation, Incidence and Prevalence, by Country

Exhibit 7-6:      Europe, Stroke, Incidence and Prevalence, by Country

Exhibit 7-7:      Europe, Depression, Prevalence, by Country

Exhibit 7-8:      Europe, Epilepsy, Incidence and Prevalence, by Country

Exhibit 7-9:      Europe, Huntington’s Disease, Incidence and Prevalence, by Country

Exhibit 7-10:    Europe, Multiple Sclerosis, Incidence and Prevalence, by Country

Exhibit 7-11:    Europe, Myasthenia Gravis, Prevalence, by Country

Exhibit 7-12:    Europe, Parkinson’s Disease, Incidence and Prevalence, by Country

Exhibit 7-13:    Europe, Schizophrenia, Prevalence, by Country

8. OPHTHALMIC DISORDERS:  CATARACTS AND GLAUCOMA

8.1 Cataracts

8.1.1 Etiology

8.1.2 Epidemiology

8.2 Glaucoma

8.2.1 Etiology

8.2.2 Epidemiology

Exhibit 8-1:      Europe, Cataracts, Incidence and Prevalence, by Country

Exhibit 8-2:      Europe, Glaucoma, Incidence and Prevalence, by Country

9. REPRODUCTIVE AND GENITOURINARY DISORDERS

9.1 Benign Prostatic Hyperplasia

9.1.1 Etiology

9.1.2 Epidemiology

9.2 Endometriosis

9.2.1 Etiology

9.2.2 Epidemiology

9.3 Erectile Dysfunction

9.3.1 Etiology

9.3.2 Epidemiology

9.4 Infertility

9.4.1 Etiology

9.4.2 Epidemiology

9.5 Urinary Incontinence

9.5.1 Etiology

9.5.2 Epidemiology

Exhibit 9-1:      Europe, Benign Prostatic Hyperplasia, Incidence and Prevalence, by Country

Exhibit 9-2:      Europe, Endometriosis, Prevalence, by Country

Exhibit 9-3:      Europe, Erectile Dysfunction, Incidence and Prevalence, by Country

Exhibit 9-4:      Europe, Infertility, Incidence and Prevalence, by Country

Exhibit 9-5:      Europe, Urinary Incontinence, Incidence and Prevalence, by Country

10. RESPIRATORY DISORDERS

10.1 Adult Respiratory Distress Syndrome

10.1.1 Etiology

10.1.2 Epidemiology

10.2 Apnea

10.2.1 Etiology

10.2.2 Epidemiology

10.3 Asthma

10.3.1 Etiology

10.3.2 Epidemiology

10.4 Cystic Fibrosis

10.4.1 Etiology

10.4.2 Epidemiology

10.5 Emphysema

10.5.1 Etiology

10.5.2 Epidemiology

10.6 Pneumothorax

10.6.1 Etiology

10.6.2 Epidemiology

10.7 Respiratory Failure

10.7.1 Etiology

10.7.2 Epidemiology

10.8 Restrictive Pulmonary Disease

10.8.1 Etiology

10.8.2 Epidemiology

Exhibit 10-1:    Europe, Adult Respiratory Distress Syndrome, Incidence and Prevalence, by Country

Exhibit 10-2:    Europe, Apnea, Incidence and Prevalence, by Country

Exhibit 10-3:    Europe, Asthma, Incidence and Prevalence, by Country

Exhibit 10-4:    Europe, Cystic Fibrosis, Incidence and Prevalence, by Country

Exhibit 10-5:    Europe, Emphysema, Prevalence, by Country

Exhibit 10-6:    Europe, Pneumothorax, Incidence and Prevalence, by Country

Exhibit 10-7:    Europe, Respiratory Failure, Incidence, by Country

Exhibit 10-8:    Europe, Restrictive Pulmonary Disease, Prevalence, by Country

11. WOUNDS

11.1 Diabetic Ulcers

11.1.1 Etiology

11.1.2 Epidemiology

11.2 Pressure Ulcers

11.2.1 Etiology

11.2.2 Epidemiology

11.3 Surgical Wounds

11.3.1 Etiology

11.3.2 Epidemiology

11.4 Traumatic Wounds

11.4.1 Etiology

11.4.1.1 Amputation

11.4.1.2 Burns

11.4.1.3 Lacerations, Contusions, and Abrasions

11.4.2 Epidemiology

Exhibit 11-1:    Europe, Diabetic Ulcers, Incidence, by Country

Exhibit 11-2:    Europe, Pressure Ulcers, Incidence, by Country

Exhibit 11-3:    Europe, Surgical Wounds, Incidence, by Country

Exhibit 11-4:    Classification of Burns, by Mechanism of Injury

Exhibit 11-5:    Europe, Traumatic Wounds, Incidence, by Country

12. SELECTED CONDITIONS CAUSED BY INFECTIOUS ORGANISMS

12.1 Bronchitis

12.1.1 Etiology

12.1.2 Epidemiology

12.2 Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome

12.2.1 Etiology

12.2.2 Epidemiology

12.3 Pneumonia

12.3.2 Etiology

12.3.1 Epidemiology

12.4 Transmissible Spongiform Encephalopathies

12.4.1 Etiology

12.4.1 Epidemiology

12.5 Tuberculosis

12.5.1 Etiology

12.5.2 Epidemiology

Exhibit 12-1:    Europe, Bronchitis, Prevalence, by Country

Exhibit 12-2:    Acquired Immune Deficiency Syndrome, Indicator Diseases

Exhibit 12-3:    European Union, Newly Diagnosed Human Immunodeficiency Virus Infections and Rates per One Million Population, by Selected Country

Exhibit 12-4:    Europe, Human Immunodeficiency Virus, Incidence and Prevalence, by Country

Exhibit 12-5:    Europe, Pneumonia, Incidence, by Country

Exhibit 12-6:    Europe, Transmissible Spongiform Encephalopathies, Incidence, by Country

Exhibit 12-7:    Europe, Tuberculosis, Incidence, by Country