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U.S. Disease Incidence and Prevalence
Report #A702 - November 2008
355 Pages – 116 Exhibits

 

Major diseases/disorders in the United States (U.S.)––from cancer and cardiovascular diseases/disorders to acquired immune deficiency syndrome and reproductive disorders––take their toll in terms of lost days from work, Medicare and Medicaid expenditures, and out-of-pocket costs.  Along with the aging of the U.S. population and increasing life spans, the incidence and prevalence of major diseases/disorders are expected to significantly impact the healthcare industry. 

This dynamic new report from Medtech Insight examines the etiology and epidemiology, hospital discharges, incidence and prevalence figures, and survival rates and mortality figures for the years 1996-2005, and 2007 (with estimated incidence and mortality figures for 2008, when available) of the most prevalent and costly diseases/disorders in the U.S. including blood disorders, cancer, cardiovascular diseases/disorders, metabolic diseases/disorders, musculoskeletal diseases, ophthalmologic diseases/conditions, neurologic and psychiatric diseases/disorders, reproductive and genitourinary disorders, respiratory diseases/disorders, sexually transmitted diseases, and skin wounds. 

In addition to proprietary data provided by Medtech Insight’s internal resources, many governmental and nonprofit organizations have provided data and hospital discharge information including the American Academy of Ophthalmology, the American Cancer Society, the American Heart Association, the American Lung Association, the Centers for Disease Control and Prevention, the National Center for Health Statistics, and the National Institutes of Health. 

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U.S. Disease Incidence and Prevalence

A702

 November 2008

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Methodology

Reports are produced exclusively by Medtech Insight, through extensive primary and secondary research among the clinicians, researchers, and competitors in the marketplace, and draw upon the industry expertise of a network of industry insiders. Medtech Insight exhaustively corroborates the data as a baseline for completing forward-looking analysis and providing insight into product, technology and market evolution.

 

TABLE OF CONTENTS

INTRODUCTION

1. BLOOD DISORDERS

1.1 Anemia

1.1.1 Iron Deficiency Anemia

1.1.1.1 Etiology

1.1.1.2 Epidemiology

1.1.2 Sickle Cell Anemia

1.1.2.1 Etiology

1.1.2.2 Epidemiology

1.1.3 Thalassemia

1.1.3.1 Etiology

1.1.3.2 Epidemiology

1.2 Hemophilia

1.2.1 Etiology

1.2.2 Epidemiology

 

Exhibit 1-1:      Iron-Deficiency Anemia, Facts and Figures, 1996-2005, and 2007

Exhibit 1-2:      Sickle Cell Anemia, Facts and Figures, 1996-2005, and 2007

Exhibit 1-3:      Thalassemia, Facts and Figures, 1996-2005, and 2007

Exhibit 1-4:      Hemophilia, Facts and Figures, 1996-2005, and 2007

Exhibit 1-5:      2008, Hemophilia, Selected Demographic Characteristics

 

2. CANCER

2.1 Incidence and Prevalence

2.1.1 Mortality Rate

2.1.2 The Cost of Cancer

2.2 Cancer Types

2.2.1 Bladder Cancer

2.2.1.1 Etiology

2.2.1.2 Epidemiology

2.2.2 Breast Cancer

2.2.2.1 Etiology

2.2.2.2 Epidemiology

2.2.3 Bronchial/Lung Cancer

2.2.3.1 Etiology

2.2.3.2 Epidemiology

2.2.4 Cervical/Uterine Cancer

2.2.4.1 Etiology

2.2.4.2 Epidemiology

2.2.5 Colon/Rectal Cancer

2.2.5.1 Etiology

2.2.5.2 Epidemiology

2.2.6 Leukemia

2.2.6.1 Etiology

2.2.6.2 Epidemiology

2.2.7 Lymphoma

2.2.7.1 Etiology

2.2.7.2 Epidemiology

2.2.8 Nervous System Cancer

2.2.8.1 Etiology

2.2.8.2 Epidemiology

2.2.9 Oral Cancer

2.2.9.1 Etiology

2.2.9.2 Epidemiology

2.2.10 Ovarian Cancer

2.2.10.1 Etiology

2.2.10.2 Epidemiology

2.2.11 Pancreatic Cancer

2.2.11.1 Etiology

2.2.11.2 Epidemiology

2.2.12 Prostate Cancer

2.2.12.1 Etiology

2.2.12.2 Epidemiology

2.2.13 Skin Cancer

2.2.13.1 Etiology

2.2.13.2 Epidemiology

 

Exhibit 2-1:      2008, Cancer Incidence, by Anatomic Site

Exhibit 2-2:      Hospital Discharge Statistics for Selected Cancers, by Anatomic Site, 1996-2005

Exhibit 2-3:      2004, Cancer Prevalence, by Anatomic Site and Gender

Exhibit 2-4:      Bladder Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-5:      Breast Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-6:      Bronchial/Lung Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-7:      Cervical Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-8:      Uterine Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-9:      Colon/Rectal Cancer, Facts and Figures, 1996-2005, and 2008 

Exhibit 2-10:    Leukemia, Facts and Figures, 1996-2005, and 2008

Exhibit 2-11:    2008, Leukemia Incidence, by Type and Gender

Exhibit 2-12:    Non-Hodgkin Lymphoma, Facts and Figures, 1996-2005, and 2008

Exhibit 2-13:    Hodgkin Lymphoma, Facts and Figures, 1996-2005, and 2008

Exhibit 2-14:    Nervous System Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-15:    Oral Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-16:    Ovarian Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-17:    Pancreatic Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-18:    Prostate Cancer, Facts and Figures, 1996-2005, and 2008

Exhibit 2-19:    Melanoma, Facts and Figures, 1996-2005, and 2008

 

3. CARDIOVASCULAR DISEASES/DISORDERS

3.1 Atherosclerosis

3.1.1 Coronary Atherosclerosis

3.1.1.1 Etiology

3.1.1.2 Epidemiology

3.1.2 Peripheral Vascular Disease

3.1.2.1 Etiology

3.1.2.2 Epidemiology

3.2 Heart Failure

3.2.1 Etiology

3.2.2 Epidemiology

3.3 Hypercholesterolemia

3.3.1 Etiology

3.3.2 Epidemiology

3.4 Hypertension

3.4.1 Etiology

3.4.2 Epidemiology

3.5 Ischemic Heart Disease

3.5.1 Angina Pectoris

3.5.1.1 Etiology

3.5.1.2 Epidemiology

3.5.2 Myocardial Infarction

3.5.2.1 Etiology

3.5.2.2 Epidemiology

3.6 Pacing Disorders

3.6.1 Arrhythmia

3.6.1.1 Etiology

3.6.1.2 Epidemiology

3.6.2 Sudden Cardiac Death

3.6.2.1 Etiology

3.6.2.2 Epidemiology

3.7 Valvular Heart Disease

3.7.1 Etiology

3.7.2 Epidemiology

 

Exhibit 3-1:      Coronary Atherosclerosis, Facts and Figures, 1996-2005, and 2007

Exhibit 3-2:      Peripheral Vascular Disease, Facts and Figures, 1996-2005, and 2007

Exhibit 3-3:      Heart Failure, Facts and Figures, 1996-2005, and 2007

Exhibit 3-4:      Hypercholesterolemia, Facts and Figures, 1996-2005, and 2007

Exhibit 3-5:      Hypertension, Facts and Figures, 1996-2005, and 2007

Exhibit 3-6:      Angina Pectoris, Facts and Figures, 1996-2005, and 2008

Exhibit 3-7:      Myocardial Infarction, Facts and Figures, 1996-2005, and 2007

Exhibit 3-8:      Arrhythmia, Facts and Figures, 1996-2005, and 2007

Exhibit 3-9:      Tachycardia, Facts and Figures, 1996-2005, and 2007

Exhibit 3-10:    2007, Sudden Cardiac Death, Facts and Figures

Exhibit 3-11:    Valvular Heart Disease, Facts and Figures, 1996-2005, and 2007

 

4. GASTRIC AND METABOLIC DISEASES/DISORDERS

4.1 Cholelithiasis

4.1.1 Etiology

4.1.2 Epidemiology

4.2 Chronic Kidney Disease

4.2.1 Etiology

4.2.2 Epidemiology

4.3 Diabetes

4.3.1 Etiology

4.3.2 Epidemiology

4.4 End-Stage Renal Disease

4.4.1 Etiology

4.4.2 Epidemiology

4.5 Gastroesophageal Reflux Disease

4.5.1 Etiology

4.5.2 Epidemiology

4.6 Irritable Bowel Syndrome

4.6.1 Etiology

4.6.2 Epidemiology

4.7 Urolithiasis

4.7.1 Etiology

4.7.2 Epidemiology

 

Exhibit 4-1:      Cholelithiasis, Facts and Figures, 1996-2005, and 2007

Exhibit 4-2:      Chronic Kidney Disease, Facts and Figures, 1996-2005, and 2007

Exhibit 4-3:      Diabetes, Facts and Figures, 1996-2005, and 2007

Exhibit 4-4:      2007, Diabetes Prevalence among Adults, by Age and Gender

Exhibit 4-5:      End-Stage Renal Disease, Facts and Figures, 1996-2005, and 2006

Exhibit 4-6:      Gastroesophageal Reflux Disease, Facts and Figures, 1996-2005, and 2007

Exhibit 4-7:      Irritable Bowel Syndrome, Facts and Figures, 1996-2005, and 2007

Exhibit 4-8:      2008, Possible Causes for Irritable Bowel Syndrome

Exhibit 4-9:      Urolithiasis, Facts and Figures, 1996-2005, and 2007

Exhibit 4-10:    Selected Predisposing Factors for Developing Kidney Stones

 

5. MUSCULOSKELETAL DISEASES/DISORDERS

5.1 Arthritis

5.1.1 Osteoarthritis

5.1.1.1 Etiology

5.1.1.2 Epidemiology

5.1.2 Rheumatoid Arthritis

5.1.2.1 Etiology

5.1.2.2 Epidemiology

5.2 Carpal Tunnel Syndrome

5.2.1 Etiology

5.2.2 Epidemiology

5.3 Duchenne Muscular Dystrophy

5.3.1 Etiology

5.3.2 Epidemiology

5.4 Osteoporosis

5.4.1 Etiology

5.4.2 Epidemiology

 

Exhibit 5-1:      Prevalence of Arthritis and Chronic Joint Symptoms in Patients Age 65 and Older in 5-Year Intervals, 2005-2030

Exhibit 5-2:      Osteoarthritis, Facts and Figures, 1996-2005, and 2007

Exhibit 5-3:      Rheumatoid Arthritis, Facts and Figures, 1996-2005, and 2007

Exhibit 5-4:      Carpal Tunnel Syndrome, Facts and Figures, 1996-2005, and 2006 and 2007

Exhibit 5-5:      Carpal Tunnel Syndrome, Cases with Time Away from Work, 1994-2006

Exhibit 5-6:      Duchenne Muscular Dystrophy, Facts and Figures, 1996-2005, and 2007

Exhibit 5-7:      2007, Incidence of Osteoporosis-Related Fractures, by Site

Exhibit 5-8:      Osteoporosis, Facts and Figures, 1996-2005, and 2007

 

6. NEUROLOGIC AND PSYCHIATRIC DISEASES/DISORDERS

6.1 Alzheimer’s Disease

6.1.1 Etiology

6.1.2 Epidemiology

6.2 Amyotrophic Lateral Sclerosis

6.2.1 Etiology

6.2.2 Epidemiology

6.3 Cerebrovascular Diseases/Disorders

6.3.1 Arteriovenous Malformation

6.3.1.1 Etiology

6.3.1.2 Epidemiology

6.3.2 Cerebral Aneurysm

6.3.2.1 Etiology

6.3.2.2 Epidemiology

6.3.3 Stroke

6.3.3.1 Etiology

6.3.3.2 Epidemiology

6.4 Epilepsy

6.4.1 Etiology

6.4.2 Epidemiology

6.5 Huntington’s Disease

6.5.1 Etiology

6.5.2 Epidemiology

6.6 Hydrocephalus

6.6.1 Etiology

6.6.2 Epidemiology

6.7 Multiple Sclerosis

6.7.1 Etiology

6.7.2 Epidemiology

6.8 Myasthenia Gravis

6.8.1 Etiology

6.8.2 Epidemiology

6.9 Parkinson’s Disease

6.9.1 Etiology

6.9.2 Epidemiology

6.10 Psychiatric Disorders

6.10.1 Attention Deficient Hyperactivity Disorder

6.10.1.1 Etiology

6.10.1.2 Epidemiology

6.10.2 Bipolar Disorder

6.10.2.1 Etiology

6.10.2.2 Epidemiology

6.10.3 Depression

6.10.3.1 Etiology

6.10.3.2 Epidemiology

6.10.4 Schizophrenia

6.10.4.1 Etiology

6.10.4.2 Epidemiology

 

Exhibit 6-1:      Alzheimer’s Disease, Facts and Figures, 1996-2005, and 2008

Exhibit 6-2:      Amyotrophic Lateral Sclerosis, Facts and Figures, 1996-2004, and 2007

Exhibit 6-3:      Arteriovenous Malformation, Facts and Figures, 1996-2005, and 2007

Exhibit 6-4:      Cerebral Aneurysm, Facts and Figures, 1996-2005, and 2007

Exhibit 6-5:      Stroke, Facts and Figures, 1996-2006, and 2008

Exhibit 6-6:      Epilepsy, Facts and Figures, 1996-2005, and 2008

Exhibit 6-7:      2007, Huntington’s Disease, Facts and Figures

Exhibit 6-8:      Hydrocephalus, Facts and Figures, 1996-2005, and 2007

Exhibit 6-9:      Multiple Sclerosis, Facts and Figures, 1996-2005, and 2007

Exhibit 6-10:    Myasthenia Gravis, Facts and Figures, 1996-2005, and 2007

Exhibit 6-11:    Parkinson’s Disease, Facts and Figures, 1996-2005, and 2007

Exhibit 6-12:    2007, Percentage of Adults Experiencing Serious Psychologic Distress, by Age and Gender

Exhibit 6-13:    Attention Deficit Hyperactivity Disorder, Facts and Figures, 1996-2005, and 2007

Exhibit 6-14:    Bipolar Disorder, Facts and Figures, 1996-2005, and 2007

Exhibit 6-15:    Depression, Facts and Figures, 1996-2005, and 2007

Exhibit 6-16:    Schizophrenia, Facts and Figures, 1996-2005, and 2007

 

7. OPHTHALMIC DISEASES/DISORDERS

7.1 Cataracts

7.1.1 Etiology

7.1.2 Epidemiology

7.2 Glaucoma

7.2.1 Etiology

7.2.2 Epidemiology

 

Exhibit 7-1:      Economic Costs of Visual Disorders and Disabilities, 1981 and 2003

Exhibit 7-2:      Cataracts, Facts and Figures, 1996-2005, and 2007

Exhibit 7-3:      2007, Cataracts, Prevalence, by Age

Exhibit 7-4:      Glaucoma, Facts and Figures, 1996-2005, and 2007

Exhibit 7-5:      2007, Glaucoma, Prevalence, by Age

 

8. REPRODUCTIVE AND GENITOURINARY DISORDERS

8.1 Female Reproductive Disorders

8.1.1 Endometriosis

8.1.1.1 Etiology

8.1.1.2 Epidemiology

8.1.2 Infertility

8.1.2.1 Etiology

8.1.2.2 Epidemiology

8.2 Male Reproductive Disorders

8.2.1 Benign Prostatic Hyperplasia

8.2.1.1 Etiology

8.2.1.2 Epidemiology

8.2.2 Erectile Dysfunction

8.2.2.1 Etiology

8.2.2.2 Epidemiology

8.2.3 Infertility

8.2.3.1 Etiology

8.2.3.2 Epidemiology

8.3 Urinary Incontinence

8.3.1 Etiology

8.3.2 Epidemiology

 

Exhibit 8-1:      Endometriosis, Facts and Figures, 1996-2005, and 2007

Exhibit 8-2:      Female Infertility, Facts and Figures, 1996-2005, and 2007

Exhibit 8-3:      Benign Prostatic Hyperplasia, Facts and Figures, 1996-2005, and 2007

Exhibit 8-4:      Direct Expenditures for Benign Prostatic Hyperplasia, by Site of Service, 1994, 1996, 1998, and 2000

Exhibit 8-5:      Erectile Dysfunction, Facts and Figures, 1996-2005, and 2007

Exhibit 8-6:      2007, Male Infertility, Facts and Figures

Exhibit 8-7:      Types of Urinary Incontinence

Exhibit 8-8:      Urinary Incontinence, Facts and Figures, 1996-2005, and 2007

 

9. RESPIRATORY DISEASES/DISORDERS

9.1 Adult Respiratory Distress Syndrome

9.1.1 Etiology

9.1.2 Epidemiology

9.2 Apnea

9.2.1 Sleep Apnea

9.2.1.1 Etiology

9.2.1.2 Epidemiology

9.2.2 Sudden Infant Death Syndrome

9.2.2.1 Etiology

9.2.2.2 Epidemiology

9.3 Asthma

9.3.1 Etiology

9.3.2 Epidemiology

9.4 Chronic Obstructive Pulmonary Disease

9.4.1 Chronic Bronchitis

9.4.1.1 Etiology

9.4.1.2 Epidemiology

9.4.2 Emphysema

9.4.2.1 Etiology

9.4.2.2 Epidemiology

9.5 Cystic Fibrosis

9.5.1 Etiology

9.5.2 Epidemiology

9.6 Infectious Diseases

9.6.1 Pneumonia

9.6.1.1 Etiology

9.6.1.2 Epidemiology

9.6.2 Tuberculosis

9.6.2.1 Etiology

9.6.2.2 Epidemiology

9.7 Pleural Disorders

9.7.1 Empyema

9.7.1.1 Etiology

9.7.1.2 Epidemiology

9.7.2 Pleural Effusion

9.7.2.1 Etiology

9.7.2.2 Epidemiology

9.7.3 Pneumothorax

9.7.3.1 Etiology

9.7.3.2 Epidemiology

9.8 Pulmonary Embolism

9.8.1 Etiology

9.8.2 Epidemiology

9.9 Respiratory Failure

9.9.1 Etiology

9.9.2 Epidemiology

9.10 Restrictive Pulmonary Disease

9.10.1 Etiology

9.10.2 Epidemiology

 

Exhibit 9-1:      Adult Respiratory Distress Syndrome, Facts and Figures, 1996-2005, and 2007

Exhibit 9-2:      Sleep Apnea, Facts and Figures, 1996-2005, and 2007

Exhibit 9-3:      2006, Sudden Infant Death Syndrome, Facts and Figures

Exhibit 9-4:      Asthma, Facts and Figures, 1996-2005, and 2007

Exhibit 9-5:      2007, Prevalence of Asthma, by Age Group and Gender

Exhibit 9-6:      2007, Prevalence of Asthma, by Age Group and Ethnicity

Exhibit 9-7:      Chronic Bronchitis, Facts and Figures, 1996-2005, and 2006

Exhibit 9-8:      Emphysema, Facts and Figures, 1996-2005, and 2006

Exhibit 9-9:      Cystic Fibrosis, Facts and Figures, 1996-2005, and 2007

Exhibit 9-10:    Pneumonia, Facts and Figures, 1996-2005, and 2007

Exhibit 9-11:    Tuberculosis, Facts and Figures, 1996-2005, and 2007

Exhibit 9-12:    Tuberculosis Cases in the United States, 1993-2007

Exhibit 9-13:    2007, Tuberculosis Cases in the United States, by Ethnicity

Exhibit 9-14:    Pleural Disorders, Facts and Figures, 1996-2005

Exhibit 9-15:    Pulmonary Embolism, Facts and Figures, 1996-2005, and 2007

Exhibit 9-16:    Respiratory Failure, Facts and Figures, 1996-2005, and 2007

Exhibit 9-17:    Restrictive Pulmonary Disease, Facts and Figures, 1996-2005, and 2007

 

10. SEXUALLY TRANSMITTED DISEASES

10.1. Genital Herpes

10.1.1 Etiology

10.1.2 Epidemiology

10.2 Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome

10.2.1 Etiology

10.2.2 Disease Progression

10.2.3 Epidemiology

 

Exhibit 10-1:    Genital Herpes, Facts and Figures, 1996-2005, and 2007

Exhibit 10-2:    Initial Physician Visits for Genital Herpes, 1996-2006

Exhibit 10-3:    Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome, Facts and Figures, 1996-2005, and 2006

Exhibit 10-4:    2008, Acquired Immune Deficiency Syndrome, Indicator/Opportunistic Diseases

Exhibit 10-5:    Estimated Acquired Immune Deficiency Syndrome Cases, by Age, Ethnicity, Gender, and Region, 2002-2006

Exhibit 10-6:    Estimated Number of Acquired Immune Deficiency Syndrome Patients, by Age, Ethnicity, Gender, and Region, 2002-2006

Exhibit 10-7:    Estimated Number of Deaths of Acquired Immune Deficiency Syndrome Patients, by Age, Ethnicity, Gender, and Region, 2002-2006

Exhibit 10-8:    2007, Percentage of Adults Tested for Human Immunodeficiency Virus, by Age and Gender

Exhibit 10-9:    2006, Adults Tested for Human Immunodeficiency Virus, by Age, Gender, and Ethnicity

 

11. SKIN WOUNDS

11.1 Factors Affecting Wound Closure

11.1.1 Intrinsic Factors

11.1.1.1 Age and Chronic Illness

11.1.1.2, Body Composition

11.1.1.3 Nutritional Status

11.1.2 Extrinsic Factors

11.1.2.1 Ambient Temperature

11.1.2.2 Desiccation/Hydration

11.1.2.3 Infection

11.1.2.4 Maceration

11.1.2.5 Medications and Other Treatment Modalities

11.1.2.6 Necrotic Tissue and Debris

11.1.2.7 Oxygen

11.1.2.8 Stress

11.1.2.9 Wound Creation and Depth

11.1.2.10 Wound Closure Techniques

11.1.2.11 Other Extrinsic Factors

11.1.3 Complications of Wound Healing

11.1.3.1 Scarring

11.1.3.2 Bleeding

11.2 Wound Types

11.2.1 Illness-Related Wounds

11.2.1.1 Etiology

11.2.1.1.1 Arterial Ulcers

11.2.1.1.2 Diabetic Ulcers

11.2.1.1.3 Venous Ulcers

11.2.1.2 Epidemiology

11.2.2 Pressure Ulcers

11.2.2.1 Etiology

11.2.2.2 Epidemiology

11.2.3 Surgical Wounds

11.2.3.1 Etiology

11.2.3.2 Epidemiology

11.2.4 Traumatic Wounds

11.2.4.1 Etiology

11.2.4.1.1 Abrasions, Contusions, and Lacerations

11.2.4.1.2 Amputations

11.2.4.1.3 Burns

11.2.4.2 Epidemiology

 

Exhibit 11-1:    Intrinsic and Extrinsic Factors Affecting Wound Closure

Exhibit 11-2:    Illness-Related Wounds, Facts and Figures, 1996-2005, and 2007

Exhibit 11-3:    Pressure Ulcers, Facts and Figures, 1996-2005, and 2007

Exhibit 11-4:    Surgical Wounds, Facts and Figures, 1996-2005, and 2007

Exhibit 11-5:    Lacerations and Other Types of Traumatic Wounds, Facts and Figures, 1996-2005, and 2007

Exhibit 11-6:    Amputations, Facts and Figures, 1996-2005, and 2007

Exhibit 11-7:    Burns, Facts and Figures, 1996-2005, and 2007

Exhibit 11-8:    Classification of Burns, by Mechanism of Injury

 

 

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